Detrimental Effect of Fungal 60-kDa Heat Shock Protein on Experimental Paracoccidioides brasiliensis Infection.

Autor: Fabrício Freitas Fernandes, Leandro Licursi de Oliveira, Taise Natali Landgraf, Gabriela Peron, Marcelo Vieira Costa, Arlete A M Coelho-Castelo, Vânia L D Bonato, Maria-Cristina Roque-Barreira, Ademilson Panunto-Castelo

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0162486 (2016)

The genus Paracoccidioides comprises species of dimorphic fungi that cause paracoccidioidomycosis (PCM), a systemic disease prevalent in Latin America. Here, we investigated whether administration of native 60-kDa heat shock protein of P. brasiliensi

Externí odkaz: https://doaj.org/article/c07fff1bddf34690900108db7890b543

Quantitation of pulmonary fungal burden in Paracoccidioides brasiliensis-infected mice by real-time PCR

Autor: Taise Natali Landgraf, Igor Emiliano Lemos de Souza, Ademilson Panunto-Castelo, Priscila C. Corrêa, Marcelo Vieira Costa, Fabrício Freitas Fernandes

Publikováno v: Revista do Instituto de Medicina Tropical de São Paulo, Volume: 61, Article number: e2, Published: 20 DEC 2018
Revista do Instituto de Medicina Tropical de São Paulo, Vol 61, Iss 0 (2018)
Revista do Instituto de Medicina Tropical de São Paulo

Although colony-forming unit (CFU) counting is widely used to quantify fungal load in tissue from animal experimentally infected with Paracoccidioides brasiliensis, several technical disadvantages have been described. Here we developed highly accurat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1807340554dc4c956eb4d1bfbc52fa94
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652019005000600&lng=en&tlng=en

Involvement of Dihydrolipoyl Dehydrogenase in the Phagocytosis and Killing of Paracoccidioides brasiliensis by Macrophages

Autor: Fabrício Freitas Fernandes, Taise Natali Landgraf, Aline Ferreira Oliveira, Ademilson Panunto-Castelo, Marcelo Vieira Costa, Wander C Ribeiro

Publikováno v: Frontiers in Microbiology, Vol 8 (2017)

Paracoccidioides brasiliensis and Paracoccidioides lutzii are fungi causing paracoccidioidomycosis (PCM), an autochthonous systemic mycosis found in Latin America. These microorganisms contain a multitude of molecules that may be associated with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855f7451649ebddfa2effd575fe7fefe
https://doi.org/10.3389/fmicb.2017.01803

Th1-Inducing Agents in Prophylaxis and Therapy for Paracoccidioidomycosis

Autor: Taise Natali Landgraf, Ademilson Panunto-Castelo, Maria Cristina Roque-Barreira, Thiago Aparecido da Silva, Fabrício Freitas Fernandes

Publikováno v: Methods in Molecular Biology ISBN: 9781493971039

Adjuvants and immunomodulatory molecules could be included in the treatment of P. brasiliensis infection. In this context, we reported that the therapeutic and/or prophylactic administration of Th1-inducing agents, such as immunomodulatory lectins an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::810d2d0c611c3fa0d133fa9ca960e5c6
https://doi.org/10.1007/978-1-4939-7104-6_12

Therapeutic effect of monophosphoryl lipid A administration on Paracoccidioides brasiliensis-infected mice

Autor: Taise Natali Landgraf, Ademilson Panunto-Castelo, Gabriela Peron, Fabrício Freitas Fernandes

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

The lack of antifungals with low toxicity and short-term therapy for patients with paracoccidioidomycosis (PCM) led us to evaluate adjuvants in immunotherapeutic intervention. We have previously shown complete Freund's adjuvant (CFA) to be therapeuti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa81e54f2d6ba4c76f9b2484b2163c09
https://pubmed.ncbi.nlm.nih.gov/27639241