Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Tairo Kashihara"'
Autor:
Satoshi Nakamura, Mihiro Takemori, Tetsu Nakaichi, Yasunori Shuto, Tairo Kashihara, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Yuka Urago, Shuka Nishina, Yuta Kobayashi, Hironori Kishida, Shoji Imamichi, Kana Takahashi, Mitsuko Masutani, Hiroyuki Okamoto, Teiji Nishio, Jun Itami, Hiroshi Igaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Accelerator-based boron neutron capture therapy (BNCT) systems employing a solid-state lithium target indicated the reduction of neutron flux over the lifetime of a target, and its reduction could represent the neutron flux model. This study
Externí odkaz:
https://doaj.org/article/a11c89c95e2e4a4884733c87071bb098
Autor:
Tairo Kashihara, Yuka Urago, Hiroyuki Okamoto, Mihiro Takemori, Hiroki Nakayama, Shohei Mikasa, Tetsu Nakaichi, Kotaro Iijima, Takahito Chiba, Junichi Kuwahara, Satoshi Nakamura, Weishan Chang, Yoshiyuki Matsui, Hiroshi Igaki
Publikováno v:
Asian Journal of Urology, Vol 11, Iss 2, Pp 286-293 (2024)
Objectives: Hydrogel spacer (HS) was developed to reduce rectal toxicities caused by radiotherapy, but has been reported to cause major adverse events. Our institute has attempted to introduce a hyaluronic acid (HA) as an alternative spacer. This stu
Externí odkaz:
https://doaj.org/article/33c31705d66b4807a2b926c177d7a3a4
Autor:
Sadamoto Zenda, Takashi Kawaguchi, Takashi Uno, Tairo Kashihara, Tetsuo Saito, Hiroyuki Okamoto, Noriyuki Kadoya, Takahiro Chiba, Shin-ei Noda, Keiichi Jingu, Keiko Shibuya, Hiroshi Igaki
Publikováno v:
BMJ Open, Vol 14, Iss 8 (2024)
Introduction In an MRI-guided linear accelerator (MR-LINAC) system, the planned doses for organs at risk and for tumours are assessed by MR imaging and re-contouring at every treatment. This allows treatment to be safer and more precise by ensuring t
Externí odkaz:
https://doaj.org/article/a1cb33c8df3043efa5c33b3010cd86e2
Autor:
Madoka Sakuramachi, Naoya Murakami, Ayaka Nagao, Kanako Kojima, Yusaku Miyata, Tairo Kashihara, Tomoya Kaneda, Kana Takahashi, Koji Inaba, Kae Okuma, Yuko Nakayama, Hiroyuki Okamoto, Mitsuya Ishikawa, Hiroshi Igaki
Publikováno v:
Journal of Contemporary Brachytherapy, Vol 15, Iss 6, Pp 465-469 (2023)
Externí odkaz:
https://doaj.org/article/de599baddb2f47dd864baa87e495958c
Autor:
Shogo Wada, Dai Ogata, Tairo Kashihara, Kae Okuma, Hirofumi Eto, Eiji Nakano, Akira Takahashi, Kenjiro Namikawa, Hiroshi Igaki, Naoya Yamazaki
Publikováno v:
Cancer Medicine, Vol 12, Iss 24, Pp 21933-21943 (2023)
Abstract Background Melanoma brain metastasis (MBM) has a poor prognosis, although recent treatments, including immune checkpoint inhibitors and targeted therapy, have improved the prognosis. However, these systemic therapies have been reported to be
Externí odkaz:
https://doaj.org/article/682e8ef166b04949b0e9c752b389a855
Autor:
Tairo Kashihara, Taisuke Mori, Tetsu Nakaichi, Satoshi Nakamura, Kimiteru Ito, Hiroaki Kurihara, Masahiko Kusumoto, Jun Itami, Seiichi Yoshimoto, Hiroshi Igaki
Publikováno v:
Cancer Medicine, Vol 12, Iss 21, Pp 20564-20572 (2023)
Abstract Background The correlation between L‐type amino acid transporter 1 (LAT1) expression and 4‐borono‐2‐18F‐fluoro‐phenylalanine (18F‐FBPA) accumulation in humans remains unclear. This study aimed to investigate the correlation bet
Externí odkaz:
https://doaj.org/article/e813a3348dfd47aabfd3286350f98a17
Autor:
Hiroshi Igaki, Satoshi Nakamura, Naoya Yamazaki, Tomoya Kaneda, Mihiro Takemori, Tairo Kashihara, Naoya Murakami, Kenjiro Namikawa, Tetsu Nakaichi, Hiroyuki Okamoto, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Ayaka Nagao, Madoka Sakuramachi, Kana Takahashi, Koji Inaba, Kae Okuma, Yuko Nakayama, Kazuaki Shimada, Hitoshi Nakagama, Jun Itami
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
This study reports the first patient treatment for cutaneous malignant melanoma using a linear accelerator-based boron neutron capture therapy (BNCT) system. A single-center open-label phase I clinical trial had been conducted using the system since
Externí odkaz:
https://doaj.org/article/c1a4c84fee7c4fe6bf99af8f0c0f21a7
Publikováno v:
Thoracic Cancer, Vol 14, Iss 2, Pp 206-209 (2023)
Abstract In lung squamous cell carcinoma, KEAP1 mutations frequently coexist with TP53 mutations. A preclinical model showed that mutations leading to the activation of the KEAP1–NRF2 pathway contribute to clinical radioresistance. However, there h
Externí odkaz:
https://doaj.org/article/efe4b2ce36724924b7c8e72bdd2df394
Autor:
Tetsu Nakaichi, Satoshi Nakamura, Kimiteru Ito, Kana Takahashi, Mihiro Takemori, Tairo Kashihara, Kouji Kunito, Naoya Murakami, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Shohei Mikasa, Teiji Nishio, Hiroyuki Okamoto, Jun Itami, Hiroaki Kurihara, Hiroshi Igaki
Publikováno v:
EJNMMI Physics, Vol 9, Iss 1, Pp 1-20 (2022)
Abstract Background 18F-FDG PET is often utilized to determine BNCT selection due to the limited availability of 18F-BPA PET, which is performed by synthesizing 18F into the boron drug used for BNCT, although the uptake mechanisms between those are d
Externí odkaz:
https://doaj.org/article/1c87c6da1bbc48a09d0d825311dc391d
Autor:
Yuri Shimizu, Naoya Murakami, Taisuke Mori, Kana Takahashi, Yuko Kubo, Seiichi Yoshimoto, Yoshitaka Honma, Satoshi Nakamura, Hiroyuki Okamoto, Kotaro Iijima, Ayaka Takahashi, Tomoya Kaneda, Tairo Kashihara, Koji Inaba, Kae Okuma, Yuko Nakayama, Hiroshi Igaki, Jun Itami
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 4, Pp 994-1001 (2022)
Abstract Purpose The clinical characteristics and prognosis of HPV‐related nasopharyngeal cancer (NPC) remain controversial. The relationship between p16 status and outcome was retrospectively investigated in the NPC patients. Materials and Methods
Externí odkaz:
https://doaj.org/article/4ab18304061e4d219e3b7363814f12fb