Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Tainah Dorina Marforio"'
Publikováno v:
Cancers, Vol 15, Iss 20, p 4944 (2023)
Carboranes have emerged as one of the most promising boron agents in boron neutron capture therapy (BNCT). In this context, in vivo studies are particularly relevant, since they provide qualitative and quantitative information about the biodistributi
Externí odkaz:
https://doaj.org/article/69adb5df13974705bf12d7204563f26f
Publikováno v:
Nanomaterials, Vol 13, Iss 11, p 1770 (2023)
Carboranes are promising agents for applications in boron neutron capture therapy (BNCT), but their hydrophobicity prevents their use in physiological environments. Here, by using reverse docking and molecular dynamics (MD) simulations, we identified
Externí odkaz:
https://doaj.org/article/6ce736bfdb604c298a541bcd55c07fba
Autor:
Alessia Marconi, Edoardo Jun Mattioli, Filippo Ingargiola, Giulia Giugliano, Tainah Dorina Marforio, Luca Prodi, Matteo Di Giosia, Matteo Calvaresi
Publikováno v:
Molecules, Vol 28, Iss 5, p 2348 (2023)
Chlorin e6 (Ce6) is among the most used sensitizers in photodynamic (PDT) and sonodynamic (SDT) therapy; its low solubility in water, however, hampers its clinical exploitation. Ce6 has a strong tendency to aggregate in physiological environments, re
Externí odkaz:
https://doaj.org/article/3c5d4ece4dcc4dc0a96bfd16898cac1c
Autor:
Alessia Marconi, Giulia Giugliano, Matteo Di Giosia, Tainah Dorina Marforio, Michele Trivini, Eleonora Turrini, Carmela Fimognari, Francesco Zerbetto, Edoardo Jun Mattioli, Matteo Calvaresi
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 919 (2023)
Temoporfin (mTHPC) is one of the most promising photosensitizers used in photodynamic therapy (PDT). Despite its clinical use, the lipophilic character of mTHPC still hampers the full exploitation of its potential. Low solubility in water, high tende
Externí odkaz:
https://doaj.org/article/facad439afc64694bdb1741ddd4791ac
Autor:
Giulia Greco, Luca Ulfo, Eleonora Turrini, Alessia Marconi, Paolo Emidio Costantini, Tainah Dorina Marforio, Edoardo Jun Mattioli, Matteo Di Giosia, Alberto Danielli, Carmela Fimognari, Matteo Calvaresi
Publikováno v:
Cells, Vol 12, Iss 3, p 392 (2023)
The combination of photodynamic therapy with chemotherapy (photochemotherapy, PCT) can lead to additive or synergistic antitumor effects. Usually, two different molecules, a photosensitizer (PS) and a chemotherapeutic drug are used in PCT. Doxorubici
Externí odkaz:
https://doaj.org/article/0801cdabe5df47a580c30982817598df
Autor:
Edoardo Jun Mattioli, Luca Ulfo, Alessia Marconi, Valentina Pellicioni, Paolo Emidio Costantini, Tainah Dorina Marforio, Matteo Di Giosia, Alberto Danielli, Carmela Fimognari, Eleonora Turrini, Matteo Calvaresi
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 68 (2022)
Temoporfin (mTHPC) is approved in Europe for the photodynamic treatment of head and neck squamous cell carcinoma (HNSCC). Although it has a promising profile, its lipophilic character hampers the full exploitation of its potential due to high tendenc
Externí odkaz:
https://doaj.org/article/615cde1e1a2c4ab38ed885ab628142f1
Autor:
Tainah Dorina Marforio, Michele Tomasini, Andrea Bottoni, Francesco Zerbetto, Edoardo Jun Mattioli, Matteo Calvaresi
Publikováno v:
Nanomaterials, Vol 13, Iss 1, p 8 (2022)
Nanoscale control of chemical reactivity, manipulation of reaction pathways, and ultimately driving the outcome of chemical reactions are quickly becoming reality. A variety of tools are concurring to establish such capability. The confinement of gue
Externí odkaz:
https://doaj.org/article/17ad619d71db44779821fdf3a3140b63
Autor:
Andrea Cantelli, Marco Malferrari, Edoardo Jun Mattioli, Alessia Marconi, Giulia Mirra, Alice Soldà, Tainah Dorina Marforio, Francesco Zerbetto, Stefania Rapino, Matteo Di Giosia, Matteo Calvaresi
Publikováno v:
Nanomaterials, Vol 12, Iss 19, p 3501 (2022)
Fullerenes are considered excellent photosensitizers, being highly suitable for photodynamic therapy (PDT). A lack of water solubility and low biocompatibility are, in many instances, still hampering the full exploitation of their potential in nanome
Externí odkaz:
https://doaj.org/article/ff83251125e543d6a9ca359e76a6ef43
Publikováno v:
Molecules, Vol 27, Iss 6, p 1916 (2022)
The persistency of COVID-19 in the world and the continuous rise of its variants demand new treatments to complement vaccines. Computational chemistry can assist in the identification of moieties able to lead to new drugs to fight the disease. Fuller
Externí odkaz:
https://doaj.org/article/c3bac3f193e742a0adca782af877fe68
Autor:
Tainah Dorina Marforio, Alessandro Calza, Edoardo Jun Mattioli, Francesco Zerbetto, Matteo Calvaresi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11567 (2021)
Molecular dynamics simulations were used to quantitatively investigate the interactions between the twenty proteinogenic amino acids and C60. The conserved amino acid backbone gave a constant energetic interaction ~5.4 kcal mol−1, while the contrib
Externí odkaz:
https://doaj.org/article/71321e2ce50e4d01ac38aa3495d3a731