Zobrazeno 1 - 10
of 539
pro vyhledávání: '"Taimen P"'
Autor:
Sofia Kalinen, Teemu Kallonen, Marianne Gunell, Otto Ettala, Ivan Jambor, Juha Knaapila, Kari T. Syvänen, Pekka Taimen, Matti Poutanen, Hannu J. Aronen, Helena Ollila, Sami Pietilä, Laura L. Elo, Tarja Lamminen, Antti J. Hakanen, Eveliina Munukka, Peter J. Boström
Publikováno v:
European Urology Open Science, Vol 62, Iss , Pp 140-150 (2024)
Background: Although prostate cancer (PCa) is the most common cancer in men in Western countries, there is significant variability in geographical incidence. This might result from genetic factors, discrepancies in screening policies, or differences
Externí odkaz:
https://doaj.org/article/59d4e96f050142fcadb2f80340ba0515
Autor:
Heidi Rausio, Alejandra Cervera, Vanina D. Heuser, Gun West, Jaana Oikkonen, Elena Pianfetti, Marta Lovino, Elisa Ficarra, Pekka Taimen, Johanna Hynninen, Rainer Lehtonen, Sampsa Hautaniemi, Olli Carpén, Kaisa Huhtinen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 51, Iss , Pp 100987- (2024)
Gene fusions are common in high-grade serous ovarian cancer (HGSC). Such genetic lesions may promote tumorigenesis, but the pathogenic mechanisms are currently poorly understood. Here, we investigated the role of a PIK3R1-CCDC178 fusion identified fr
Externí odkaz:
https://doaj.org/article/2d652944943a4b03bb95ad24b38668fe
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28949- (2024)
Background: Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are prevalent conditions affecting a significant portion of the male population, particularly with advancing age. Traditional diagnostic methods, such as digital rectal examinat
Externí odkaz:
https://doaj.org/article/1f9cc206ae66449498d4229cda81e816
Publikováno v:
In Clinica Chimica Acta 1 June 2024 559
Autor:
Antti Viitala, Michael Gabriel, Kirsi Joronen, Gaber Komar, Antti Perheentupa, Teija Sainio, Jutta Huvila, Pekka Pikander, Pekka Taimen, Roberto Blanco Sequeiros
Publikováno v:
International Journal of Hyperthermia, Vol 40, Iss 1 (2023)
AbstractPurpose Magnetic resonance – high-intensity focused ultrasound (MR-HIFU) is a noninvasive treatment option for symptomatic uterine leiomyomas. Currently, pretreatment MRI is used to assess tissue characteristics and predict the most likely
Externí odkaz:
https://doaj.org/article/1b87f681bace451bac6fa72da9c82cf1
Autor:
Anna Aakula, Aleksi Isomursu, Christian Rupp, Andrew Erickson, Nikhil Gupta, Otto Kauko, Pragya Shah, Artur Padzik, Yuba Raj Pokharel, Amanpreet Kaur, Song‐Ping Li, Lloyd Trotman, Pekka Taimen, Antti Rannikko, Jan Lammerding, Ilkka Paatero, Tuomas Mirtti, Johanna Ivaska, Jukka Westermarck
Publikováno v:
Molecular Oncology, Vol 17, Iss 6, Pp 1007-1023 (2023)
While organ‐confined prostate cancer (PCa) is mostly therapeutically manageable, metastatic progression of PCa remains an unmet clinical challenge. Resistance to anoikis, a form of cell death initiated by cell detachment from the surrounding extrac
Externí odkaz:
https://doaj.org/article/3465127f6de14d22a287259d5153e9f9
Autor:
Dai, Zhenzhen, Jambor, Ivan, Taimen, Pekka, Pantelic, Milan, Elshaikh, Mohamed, Rogers, Craig, Ettala, Otto, Boström, Peter, Aronen, Hannu, Merisaari, Harri, Wen, Ning
Purpose: We aimed to develop deep machine learning (DL) models to improve the detection and segmentation of intraprostatic lesions (IL) on bp-MRI by using whole amount prostatectomy specimen-based delineations. We also aimed to investigate whether tr
Externí odkaz:
http://arxiv.org/abs/2010.15233
Autor:
Caroline Le Dour, Maria Chatzifrangkeskou, Coline Macquart, Maria M. Magiera, Cécile Peccate, Charlène Jouve, Laura Virtanen, Tiina Heliö, Katriina Aalto-Setälä, Silvia Crasto, Bruno Cadot, Déborah Cardoso, Nathalie Mougenot, Daniel Adesse, Elisa Di Pasquale, Jean-Sébastien Hulot, Pekka Taimen, Carsten Janke, Antoine Muchir
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Lamin A/C gene mutations cause dilated cardiomyopathy associated with cofilin-1 phosphorylation and actin destabilization. Here, the authors show that phosphorylated cofilin-1 blunts the MRTF-A/SRF axis, leading to decreased tubulin acetylation and a
Externí odkaz:
https://doaj.org/article/ef932080f9164edd9c93891a4153a646
Autor:
Sneha Parekh, Parita Ratnani, Ugo Falagario, Dara Lundon, Deepshikha Kewlani, Jordan Nasri, Zach Dovey, Dimitrios Stroumbakis, Daniel Ranti, Ralph Grauer, Stanislaw Sobotka, Adriana Pedraza, Vinayak Wagaskar, Lajja Mistry, Ivan Jambor, Anna Lantz, Otto Ettala, Armando Stabile, Pekka Taimen, Hannu J. Aronen, Juha Knaapila, Ileana Montoya Perez, Giorgio Gandaglia, Alberto Martini, Wolfgang Picker, Erik Haug, Luigi Cormio, Tobias Nordström, Alberto Briganti, Peter J. Boström, Giuseppe Carrieri, Kenneth Haines, Michael A. Gorin, Peter Wiklund, Mani Menon, Ash Tewari
Publikováno v:
European Urology Open Science, Vol 41, Iss , Pp 45-54 (2022)
Background: The European Association of Urology guidelines recommend the use of imaging, biomarkers, and risk calculators in men at risk of prostate cancer. Risk predictive calculators that combine multiparametric magnetic resonance imaging with preb
Externí odkaz:
https://doaj.org/article/0bde958af674403885591b65ac4c03df
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