Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Taiki Nanya"'
Autor:
Yukitaka, Ideyama 1, Masafumi, Kudoh 1, Kyoko, Tanimoto 1, Yoko, Susaki 1, Taiki, Nanya 1, Takahito, Nakahara 1, Hiroko, Ishikawa 1, Takashi, Fujikura 1, Hideyuki, Akaza 2, Hisataka, Shikama 1, *
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(2):213-220
Autor:
Masafumi Kudoh, Hiroko Ishikawa, Takahito Nakahara, Hideyuki Akaza, Yukitaka Ideyama, Taiki Nanya, Hisataka Shikama, Takashi Fujikura, Kyoko Tanimoto, Yoko Susaki
Publikováno v:
Japanese Journal of Pharmacology. 79:213-220
The concentrations of androstenedione and dehydroepiandrosterone, products of C17-20 lyase, in the medium after a 6-hr incubation of NCI-H295 cells were decreased by YM116 (2-(1H-imidazol-4-ylmethyl)-9H-carbazole) (IC50: 3.6 and 2.1 nM) and ketoconaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767f66f4d5401d42dc756d0bb7cc947f
https://doi.org/10.1254/jjp.79.213
https://doi.org/10.1254/jjp.79.213
Autor:
Minoru Okada, Takahito Nakahara, Takashi Fujikura, Hideyuki Akaza, Yoko Susaki, Yukitaka Ideyama, Taiki Nanya, Toru Yoden, Hiroko Ishikawa, Kyoko Tanimoto, Hisataka Shikama, Masafumi Kudoh
Publikováno v:
The Prostate. 37:10-18
BACKGROUND The purpose of this study was to determine the effects of a nonsteroidal C17–20 lyase inhibitor, 2-(1H-imidazol-4-ylmethyl)-9H-carbazole (YM116), on serum concentrations of androgens and ventral prostatic weight in rats. METHODS Serum co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e657856cbb981a40f1f6b60d39f6f16
https://doi.org/10.1002/(sici)1097-0045(19980915)37:1<10::aid-pros3>3.0.co
https://doi.org/10.1002/(sici)1097-0045(19980915)37:1<10::aid-pros3>3.0.co
Autor:
Takashi Fujikura, Hisataka Shikama, Masafumi Kudoh, Taiki Nanya, Yoko Susaki, Yukitaka Ideyama, Masamichi Mori
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 58:189-194
The proliferation of MCF-7, human breast cancer cell line, was stimulated by testosterone and estradiol. The aromatase activity in MCF-7 cells, which catalysed the conversion of testosterone to estradiol, was inhibited by a novel non-steroidal aromat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f79c3ce17a2b2bfd2538bc31f3cc47c
https://doi.org/10.1016/0960-0760(96)00023-4
https://doi.org/10.1016/0960-0760(96)00023-4
Autor:
Takashi Fujikura, Masafumi Kudoh, Hisataka Shikama, Yoko Susaki, Taiki Nanya, Yukitaka Ideyama, Minoru Okada
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 54:265-271
YM511 inhibited aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s: 0.4 and 0.12 nM, respectively). YM511 was about 3 times more potent than other aromatase inhibitors, such as CGS 16949A, CGS 20267 and R 76713.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b37360a09a3ecd5d07d0618c9a873b
https://doi.org/10.1016/0960-0760(95)00136-n
https://doi.org/10.1016/0960-0760(95)00136-n
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 63(1-3)
Estrogen deprivation therapy effectively prevents progress of endometriosis but the precise mechanism by which estrogen stimulates growth of endometriotic implants is still unknown. We examined effects of hypoestrogenic state induced by ovariectomy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d84cdcc28fb03238916f77f6199e1fa
https://pubmed.ncbi.nlm.nih.gov/9449208
https://pubmed.ncbi.nlm.nih.gov/9449208
Autor:
Tetsushi Abe, Takashi Fujikura, Eiji Kawaminami, Yukitaka Ideyama, Minoru Okada, Taiki Nanya, Toichi Takenaka, Masafumi Kudo, Yasuo Isomura, Yoko Susaki
Publikováno v:
Japanese Journal of Pharmacology. 61:176
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eef0321167f191512f3bc188391af85
https://doi.org/10.1016/s0021-5198(19)51591-8
https://doi.org/10.1016/s0021-5198(19)51591-8