Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Taiki Nagano"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Cellular senescence is defined as irreversible growth arrest induced by various stress, such as DNA damage and oxidative stress. Senescent cells exhibit various characteristic morphological changes including enlarged morphology. In our recen
Externí odkaz:
https://doaj.org/article/29318c9ac0144953bd14b72dff83a2a5
Autor:
Masayuki Nakano, Akio Nakashima, Taiki Nagano, Shintaro Ishikawa, Ushio Kikkawa, Shinji Kamada
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80411 (2013)
Branched-chain amino acids (BCAAs) have been applied as an oral supplementation to patients with liver cirrhosis. BCAAs not only improve nutritional status of patients but also decrease the incidence of liver cancer. Mammalian target of rapamycin (mT
Externí odkaz:
https://doaj.org/article/e42ff7eee4094d95bab0ee587934ecc2
Autor:
Taiki Nagano, Shinji Kamada, Tetsushi Iwasaki, Shione Kuwaba, Kentaro Mio, Taiichi Osumi, Yuto Awai
Publikováno v:
Molecular Biology of the Cell
Cellular senescence is a state of permanent proliferative arrest induced by a variety of stresses, such as DNA damage. The transcriptional activity of p53 has been known to be essential for senescence induction. It remains unknown, however, whether a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693f904ad4847c12f93b8afa5f5e352c
http://europepmc.org/articles/PMC8693961
http://europepmc.org/articles/PMC8693961
Autor:
Yuto Awai, Akio Nakashima, Shinji Kamada, Anju Terachi, Shione Kuwaba, Kengo Onishi, Shota Asano, Kiyoko Nagai, Tetsushi Iwasaki, Ushio Kikkawa, Ryoko Katasho, Taiki Nagano
Publikováno v:
The Journal of Biological Chemistry
Although senescent cells display various morphological changes including vacuole formation, it is still unclear how these processes are regulated. We have recently identified the gene, lymphocyte antigen 6 complex, locus D (LY6D), to be upregulated s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38cfb03d969dcb124bb19558951cb6a9
https://hdl.handle.net/20.500.14094/90008552
https://hdl.handle.net/20.500.14094/90008552
Autor:
Taiki Nagano1, Tetsushi Iwasaki1,2,3, Kengo Onishi2, Yuto Awai3, Anju Terachi2, Shione Kuwaba3, Shota Asano2, Ryoko Katasho2, Kiyoko Nagai1, Akio Nakashima1,4, Ushio Kikkawa1,4, Shinji Kamada1,2,3 skamada@kobe-u.ac.jp
Publikováno v:
Journal of Biological Chemistry. Jan-Jun2021, Vol. 296, p1-15. 15p.
Autor:
Kosuke Kawai, Shinji Kamada, Mizuki Kinugasa, Akio Nakashima, Tetsushi Iwasaki, Yuto Awai, Ushio Kikkawa, Taiki Nagano, Kengo Onishi
Publikováno v:
Journal of Cell Science.
Cellular senescence is a complex stress response characterized by permanent loss of proliferative capacity and is implicated in age-related disorders. Although the transcriptional activity of p53 (encoded by TP53) is known to be vital for senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac28d5677c6ebcee4a6a617ef0429cc
https://doi.org/10.1242/jcs.196469
https://doi.org/10.1242/jcs.196469
Autor:
Anju Terachi, Shinji Kamada, Akio Nakashima, Tetsushi Iwasaki, Shunsuke Yamao, Ryoko Katasho, Ushio Kikkawa, Kosuke Kawai, Haruki Itoh, Hidetora Yarimizu, Taiki Nagano
Publikováno v:
Life Science Alliance
This study reveals a novel role of d-amino acid oxidase in promoting cellular senescence induced by genotoxic stresses via enzymatic generation of reactive oxygen species.
d-amino acid oxidase (DAO) is a flavin adenine dinucleotide (FAD)–depen
d-amino acid oxidase (DAO) is a flavin adenine dinucleotide (FAD)–depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4ad6c6164e4cc08b9a7d87ed10e033
https://hdl.handle.net/20.500.14094/90005548
https://hdl.handle.net/20.500.14094/90005548
Autor:
Ayano Itai, Miwa Yamauchi, Shinji Kamada, Taiki Nagano, Masahiro Oka, Masanobu Sakaguchi, Tetsushi Iwasaki, Zhu Liang
Publikováno v:
Journal of Dermatological Science. 86:e94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::981c49f9ef469395d5ee8b519d8414e9
https://doi.org/10.1016/j.jdermsci.2017.02.275
https://doi.org/10.1016/j.jdermsci.2017.02.275
Autor:
Akio Nakashima, Ushio Kikkawa, Shinji Kamada, Taiki Nagano, Shin-ichi Hisanaga, Toshiaki Hashimoto
Publikováno v:
Cell cycle (Georgetown, Tex.). 12(16)
Cyclins control cell cycle progression by regulating the activity of cyclin-dependent kinases (Cdks). Cyclin I is a member of the cyclin family because of the presence of a cyclin box motif. It has been suggested that Cyclin I is involved in various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4123aaa85f382047f306984e60a6cdf6
https://pubmed.ncbi.nlm.nih.gov/23907122
https://pubmed.ncbi.nlm.nih.gov/23907122
Autor:
Shintaro Ishikawa, Akio Nakashima, Masayuki Nakano, Ushio Kikkawa, Shinji Kamada, Taiki Nagano
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80411 (2013)
PLoS ONE
PLoS ONE
Branched-chain amino acids (BCAAs) have been applied as an oral supplementation to patients with liver cirrhosis. BCAAs not only improve nutritional status of patients but also decrease the incidence of liver cancer. Mammalian target of rapamycin (mT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca6e17c8ddfb66484756379760ddc3f
http://europepmc.org/articles/PMC3819289?pdf=render
http://europepmc.org/articles/PMC3819289?pdf=render