Výsledky vyhledávání - "Taijun Kohno"

Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and ΔF508 CFTR

Autor: Akiko Niibori, Tsukasa Okiyoneda, Masahito Ikawa, Kazutsune Harada, Marek Duszyk, Mary Ann Suico, Marek Michalak, Tsuyoshi Shuto, Taijun Kohno, Hirofumi Kai, Ikuo Wada

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1783:1585-1594

Cystic fibrosis (CF) is caused by the mutation in CF transmembrane conductance regulator (CFTR), a cAMP-dependent Cl(-) channel at the plasma membrane of epithelium. The most common mutant, DeltaF508 CFTR, has competent Cl(-) channel function, but fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5bff9dcb91e54967cc29d38162022f
https://doi.org/10.1016/j.bbamcr.2008.04.002

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Bafilomycin A1-sensitive pathway is required for the maturation of cystic fibrosis transmembrane conductance regulator

Autor: Hiroyuki Kusuhara, Tsukasa Okiyoneda, Yasuaki Hashimoto, Akiko Niibori, Taijun Kohno, Hirofumi Kai, Tappei Takada, Tsuyoshi Shuto, Yuichi Sugiyama, Kazutsune Harada, Mary Ann Suico

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1763(10):1017-1023

Cystic fibrosis (CF) is the most common lethal genetic disease in Caucasians caused by the trafficking defects of CF transmembrane conductance regulator (CFTR), which is a cAMP-dependent Cl − channel at the plasma membrane. The trafficking pathway

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a169ef3e0422da99693522ea1466104

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