Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Taijie Guo"'
Autor:
Yan-ru Cui, Shao-jie Wang, Tiancheng Ma, Peihong Yu, Jun Chen, Taijie Guo, Genyi Meng, Biao Jiang, Jiajia Dong, Jia Liu
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
The FDA-approved anti-cancer drug, KPT330, can indirectly inhibit Cas9 by interfering with Cas9 mRNA nuclear export and help reduce off-target editing in cells.
Externí odkaz:
https://doaj.org/article/29697c6c0d53413594c87f69c4733c09
Autor:
Ye Xin, Shuo Liu, Yan Liu, Zhen Qian, Hongyue Liu, Bingjie Zhang, Taijie Guo, Garth J. Thompson, Raymond C. Stevens, K. Barry Sharpless, Jiajia Dong, Wenqing Shui
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The recently developed double-click reaction sequence [G. Meng et al. , Nature 574 , 86–89 (2019)] is expected to vastly expand the number and diversity of synthetically accessible 1,2,3-triazole derivatives. However, it remains elusive how to rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc3d9f3cb03d64d951c4a389b4227a5
https://doi.org/10.1073/pnas.2220767120
https://doi.org/10.1073/pnas.2220767120
Autor:
Zichen Liu, Irene Lepori, Mahendra D. Chordia, Brianna E. Dalesandro, Taijie Guo, Jiajia Dong, M. Sloan Siegrist, Marcos M. Pires
Publikováno v:
Angewandte Chemie. 135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f471ae89417e38ade534b2d9f29eff9
https://doi.org/10.1002/ange.202217777
https://doi.org/10.1002/ange.202217777
Autor:
Zichen Liu, Irene Lepori, Brianna E. Dalesandro, Mahendra D. Chordia, Taijie Guo, Karl Barry Sharpless, Jiajia Dong, M. Sloan Siegrist, Marcos M. Pires
The general lack of permeability of small molecules observed forMycobacterium tuberculosis(Mtb) is most commonly ascribed to its unique cell envelope. More specifically, the outer mycomembrane is hypothesized to be the principal determinant for acces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f6a0e91fe32dc9fd1f9667f76b2640a
https://doi.org/10.1101/2022.10.12.509737
https://doi.org/10.1101/2022.10.12.509737
Autor:
Marie-Claire Giel, Jiajia Dong, Tatiana P. Soares da Costa, Emily R. R. Mackie, Christopher J. Smedley, Taijie Guo, John E. Moses
Publikováno v:
Angewandte Chemie. 132:1197-1202
The boom in growth of 1,4-disubstituted triazole products, in particular, since the early 2000's, can be largely attributed to the birth of click chemistry and the discovery of the CuI -catalyzed azide-alkyne cycloaddition (CuAAC). Yet the synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84af5d5abbddfa236004356f2ea6ff63
https://doi.org/10.1002/ange.201912728
https://doi.org/10.1002/ange.201912728
Autor:
Yan-ru Cui, Shao-jie Wang, Tiancheng Ma, Peihong Yu, Jun Chen, Taijie Guo, Genyi Meng, Biao Jiang, Jiajia Dong, Jia Liu
Publikováno v:
Communications biology. 5(1)
CRISPR-based genome engineering tools are associated with off-target effects that constitutively active Cas9 protein may instigate. Previous studies have revealed the feasibility of modulating Cas9-based genome- and base-editing tools using protein o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67b22e90ddb723525531a0d2ffc6a7c
https://pubmed.ncbi.nlm.nih.gov/35301428
https://pubmed.ncbi.nlm.nih.gov/35301428
Autor:
Meng Genyi, Jiajia Dong, Zhan Xiongjie, Yang Qian, Long Xu, Taijie Guo, Ma Tiancheng, K. Barry Sharpless
Publikováno v:
Angewandte Chemie International Edition. 57:2605-2610
Sulfuryl fluoride, SO2 F2 , has been found to derivatize phenols in all kinds of environments, even those in highly functional molecules. We now report that a solid fluorosulfuryl imidazolium triflate salt delivers the same "F-SO2 +" fragment to Nu-H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8901a042fa30776627ef48ed45a1d8e
https://doi.org/10.1002/anie.201712429
https://doi.org/10.1002/anie.201712429
Autor:
Marie-Claire Giel, Christopher J. Smedley, Emily R. R. Mackie, Taijie Guo, Jiajia Dong, Tatiana P. Soares da Costa, John E. Moses
The 1,2,3-triazole group is one of the most important connective linkers and functional aromatic heterocycles in modern chemistry. The boom in growth of, in particular, 1,4-disubstituted triazole products since the early 2000’s, can be largely attr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551d023f475300d3b70de16e7647575b
https://doi.org/10.26434/chemrxiv.9937754
https://doi.org/10.26434/chemrxiv.9937754
Autor:
Taijie Guo, Yucheng Shen, Jiong Zhang, Jiajia Dong, Meng Genyi, Sharpless Karl Barry, Ma Tiancheng
Publikováno v:
Nature. 574(7776)
Click chemistry is a concept in which modular synthesis is used to rapidly find new molecules with desirable properties1. Copper(i)-catalysed azide–alkyne cycloaddition (CuAAC) triazole annulation and sulfur(vi) fluoride exchange (SuFEx) catalysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec3d1c962f1bf224821202944955201
https://pubmed.ncbi.nlm.nih.gov/31844266
https://pubmed.ncbi.nlm.nih.gov/31844266
Publikováno v:
Curr Protoc Chem Biol
Sulfur (VI) fluoride exchange (SuFEx) is a new family of click chemistry reactions that relies on readily available sulfuryl fluoride (SO2 F2 ) and ethenesulfonyl fluoride to build diverse chemical structures bearing the SVI -F motif, such as fluoros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7510c161d353fb3700779b08bcab67a
https://pubmed.ncbi.nlm.nih.gov/30816629
https://pubmed.ncbi.nlm.nih.gov/30816629