Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Taija af Hällström"'
Autor:
Karina Barreiro, Om Prakash Dwivedi, Sami Valkonen, Per‐Henrik Groop, Tiinamaija Tuomi, Harry Holthofer, Antti Rannikko, Marjo Yliperttula, Pia Siljander, Saara Laitinen, Elina Serkkola, Taija af Hällström, Carol Forsblom, Leif Groop, Maija Puhka
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 12, Pp n/a-n/a (2021)
Abstract Urinary extracellular vesicles (uEV) are a topical source of non‐invasive biomarkers for health and diseases of the urogenital system. However, several challenges have become evident in the standardization of uEV pipelines from collection
Externí odkaz:
https://doaj.org/article/53420f988cd84400b27fc301f6eca21a
Autor:
Erkko Ylösmäki, Sergio Lavilla-Alonso, Sari Jäämaa, Markus Vähä-Koskela, Taija af Hällström, Akseli Hemminki, Johanna Arola, Heikki Mäkisalo, Kalle Saksela
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54506 (2013)
MicroRNAs (miRNAs) are important and ubiquitous regulators of gene expression that can suppress their target genes by translational inhibition as well as mRNA destruction. Cell type-specific miRNA expression patterns have been successfully exploited
Externí odkaz:
https://doaj.org/article/6985d9f4595c4e529b6edbbc82fed5be
Autor:
Angelo M. De Marzo, Marikki Laiho, Ibrahim Kulac, Taija af Hällström, Hester Liu, Alexandra Brodie, Baoyan Bai, Qizhi Zheng, Paul Sirajuddin, Gunes Guner
Supplementary table ("clinicopathological features of cases on the TMAs") and figures (1; "increased 5'ETS/45S CISH signal in cancer glands", 2; "scatterplot showing correlation between 5ʹETS/45S CISH levels by quantitative image analysis and quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937b055a1c3f11f0e584ad248dbd0eda
https://doi.org/10.1158/1541-7786.22511502
https://doi.org/10.1158/1541-7786.22511502
Autor:
Marikki Laiho, Paul Sirajuddin, Henna M. Moore, Taija af Hällström, Zhewei Zhang, Sari Jäämaa, Hester Liu, Laureen Colis, Karita Peltonen
Activation of the p53 pathway has been considered a therapeutic strategy to target cancers. We have previously identified several p53-activating small molecules in a cell-based screen. Two of the compounds activated p53 by causing DNA damage, but thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28e7d749d4d008017b523486220b60e1
https://doi.org/10.1158/1535-7163.c.6536851.v1
https://doi.org/10.1158/1535-7163.c.6536851.v1
Autor:
Marikki Laiho, Paul Sirajuddin, Henna M. Moore, Taija af Hällström, Zhewei Zhang, Sari Jäämaa, Hester Liu, Laureen Colis, Karita Peltonen
Supplementary Figures S1-S3. Supplementary Figure 1. BMH-9, BMH-22 and BMH-23 cause a reduction in RPA194 half life. Supplementary Figure 2. BMH-9, BMH-22 and BMH-23 do not activate the DNA damage response. Supplementary Figure 3. p53 activation by N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b53ba1e13f4e77c38c059113b3a5987
https://doi.org/10.1158/1535-7163.22501639.v1
https://doi.org/10.1158/1535-7163.22501639.v1
Autor:
Angelo M. De Marzo, Marikki Laiho, Ibrahim Kulac, Taija af Hällström, Hester Liu, Alexandra Brodie, Baoyan Bai, Qizhi Zheng, Paul Sirajuddin, Gunes Guner
This report develops an analytically validated chromogenic in situ hybridization (CISH) assay using branched DNA signal amplification (RNAscope) for detecting the expression of the 5′ external transcribed spacer (ETS) of the 45S ribosomal (r) RNA p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4270e7ab9cae73aa600f0b680c5434cd
https://doi.org/10.1158/1541-7786.c.6539958.v1
https://doi.org/10.1158/1541-7786.c.6539958.v1
Autor:
Peter Mohr, Klaus Pantel, Janina Staub, Harriet Wikman, Taija af Hällström, Julia-Christina Stadler, Stefan W. Schneider, Svenja Schneegans, Alexander Sartori, Evi Lianidou, Leonie Bluhm, Mikael Kubista, Jonathan M Shaffer, Darryl Irwin, Katharina Besler, Rüdiger Greinert, Elina Serkkola, Lelia Lück, Beate Volkmer, Christoffer Gebhardt, Melanie A. Hussong, Markus Sprenger-Haussels
Publikováno v:
Molecular Oncology, Vol 14, Iss 5, Pp 1001-1015 (2020)
Molecular Oncology
Molecular Oncology
The combination of liquid biomarkers from a single blood tube can provide more comprehensive information on tumor development and progression in cancer patients compared to single analysis. Here, we evaluated whether a combined analysis of circulatin
Autor:
Antti Rannikko, Carol Forsblom, Sami Valkonen, Pia Siljander, Marjo Yliperttula, Harry Holthöfer, Om Prakash Dwivedi, Saara Laitinen, Tiinamaija Tuomi, Leif Groop, Per-Henrik Groop, Taija af Hällström, Elina Serkkola, Maija Puhka, Karina Barreiro
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 12, Pp n/a-n/a (2021)
Journal of Extracellular Vesicles
Journal of extracellular vesicles
Journal of Extracellular Vesicles
Journal of extracellular vesicles
Urinary extracellular vesicles (uEV) are a topical source of non-invasive biomarkers for health and diseases of the urogenital system. However, several challenges have become evident in the standardization of uEV pipelines from collection of urine to
Autor:
Khalid Saeed, Antti Rannikko, Taija af Hällström, Johan Lundin, Olli-Pekka Kallioniemi, Petrus Järvinen, Tuomas Mirtti, Riku Turkki, Harry Nisen, Teijo Pellinen, Poojitha Ojamies, Päivi Östling, Kimmo Taari, Samuli Eldfors
Publikováno v:
International Journal of Cancer. 144:1356-1366
Renal cell cancer (RCC) has become a prototype example of the extensive intratumor heterogeneity and clonal evolution of human cancers. However, there is little direct evidence on how the genetic heterogeneity impacts on drug response profiles of the
Autor:
Emmy W. Verschuren, Katja Närhi, Jenni Lahtela, Simon Anders, Annabrita Hemmes, Jan Trapman, Antti Rannikko, Jari Räsänen, Nina Linder, Riku Turkki, Ashwini S. Nagaraj, Johan Lundin, Kaisa Salmenkivi, Wolfgang Sommergruber, Mikko I. Mäyränpää, Petra W van Duijn, Taija af Hällström, Virva Uotinen, Elina Parri, Olli Kallioniemi
Publikováno v:
The Journal of Pathology. 245:101-113
A key question in precision medicine is how functional heterogeneity in solid tumours informs therapeutic sensitivity. We demonstrate that spatial characteristics of oncogenic signalling and therapy response can be modelled in precision-cut slices fr