Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Taiichi Sakamoto"'
Autor:
Koji Umezawa, Rena Ikeda, Taiichi Sakamoto, Yuya Enomoto, Yuma Nihashi, Sayaka Shinji, Takeshi Shimosato, Hiroshi Kagami, Tomohide Takaya
Publikováno v:
BioTech, Vol 13, Iss 2, p 11 (2024)
A myogenetic oligodeoxynucleotide (myoDN), iSN04 (5′-AGA TTA GGG TGA GGG TGA-3′), is a single-stranded 18-base telomeric DNA that serves as an anti-nucleolin aptamer and induces myogenic differentiation, which is expected to be a nucleic acid dru
Externí odkaz:
https://doaj.org/article/17242a6b91614fc2a71b427d78c59071
Autor:
Ryo Amano, Masato Namekata, Masataka Horiuchi, Minami Saso, Takuya Yanagisawa, Yoichiro Tanaka, Farhana Ishrat Ghani, Masakuni Yamamoto, Taiichi Sakamoto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Fibroblast growth factor 5 (FGF5) is a crucial regulator of hair growth and an oncogenic factor in several human cancers. To generate FGF5 inhibitors, we performed Systematic Evolution of Ligands by EXponential enrichment and obtained novel
Externí odkaz:
https://doaj.org/article/75c971d601c64b4c9394e84857b8cf47
Autor:
Mayumi Minamisawa, Yuma Sato, Eitarou Ishiguro, Tetsuyuki Taniai, Taiichi Sakamoto, Gota Kawai, Takashi Saito, Takaomi C. Saido
Publikováno v:
Life, Vol 12, Iss 1, p 34 (2021)
In this study, we observed disease progression, changes in the gut microbiota, and interactions among the brain, liver, pancreas, and intestine in a mouse model of Alzheimer’s disease (AD), in addition to attempting to inhibit disease progression t
Externí odkaz:
https://doaj.org/article/3e927d0df2e34523ab0143f02a3341e2
Autor:
Ryo Amano, Kazuteru Aoki, Shin Miyakawa, Yoshikazu Nakamura, Tomoko Kozu, Gota Kawai, Taiichi Sakamoto
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract RNA aptamers are RNA molecules that bind to a target molecule with high affinity and specificity using uniquely-folded tertiary structures. RNA aptamers are selected from an RNA pool typically comprising up to 1015 different sequences genera
Externí odkaz:
https://doaj.org/article/a719e1e805e04e56860ef285c5f3fcd1
Autor:
Nobukazu Nameki, Masayuki Takizawa, Takayuki Suzuki, Shoko Tani, Naohiro Kobayashi, Taiichi Sakamoto, Yutaka Muto, Kanako Kuwasako
Publikováno v:
Protein Science. 31
Autor:
Nobukazu, Nameki, Masayuki, Takizawa, Takayuki, Suzuki, Shoko, Tani, Naohiro, Kobayashi, Taiichi, Sakamoto, Yutaka, Muto, Kanako, Kuwasako
Publikováno v:
Protein science : a publication of the Protein Society. 31(10)
SURP domains are exclusively found in splicing-related proteins in all eukaryotes. SF3A1, a component of the U2 snRNP, has two tandem SURP domains, SURP1, and SURP2. SURP2 is permanently associated with a specific short region of SF3A3 within the SF3
Autor:
Yoichiro Tanaka, Junichi Fukunaga, Yusuke Nomura, Tomoko Kozu, Yoshikazu Nakamura, Taiichi Sakamoto, Hidetaka Torigoe
Publikováno v:
FEBS Letters. 594:3477-3489
MTG8 (RUNX1T1) is a fusion partner of AML1 (RUNX1) in the leukemic chromosome translocation t(8;21). The AML1-MTG8 fusion gene encodes a chimeric transcription factor. One of the highly conserved domains of MTG8 is TAFH which possesses homology with
Autor:
Rintaro Iwata Hara, Yusuke Maeda, Kazutaka Nishina, Taiichi Sakamoto, Takanori Yokota, Kie Yoshida-Tanaka, Takeshi Wada
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 38:338-348
Properties of cationic peptides bearing amino or guanidino groups with various side chain lengths that bind to double stranded RNAs (dsRNAs) were investigated. Peptides with shorter side chain lengths effectively bound to dsRNAs (12mers) increasing t
Autor:
Kazuei Igarashi, Gota Kawai, Kiryu Asakura, Robert J. Linhardt, Taiichi Sakamoto, Tomomi Furihata, Toshihiko Toida, Masataka Imamura, Katsutoshi Yamaguchi, Kyohei Higashi
Publikováno v:
Biochemical Journal. 475:3797-3812
Glycosaminoglycans (GAGs), a group of structurally related acidic polysaccharides, are primarily found as glycan moieties of proteoglycans (PGs). Among these, chondroitin sulfate (CS) and dermatan sulfate, side chains of PGs, are widely distributed i
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2263
Translation initiation, in both eukaryotes and bacteria, requires essential elements such as mRNA, ribosome , initiator tRNA, and a set of initiation factors. For each domain of life, canonical mechanisms and signals are observed to initiate protein