Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Taigo Horiguchi"'
Autor:
Shengjian Jin, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Hiroko Hagita, Motoharu Sarubo, Natsumi Fujiwara, Guangying Qi, Naozumi Ishimaru, Yasusei Kudo
Publikováno v:
Cancer Medicine, Vol 12, Iss 24, Pp 22156-22169 (2023)
Abstract Background Comprehending the molecular mechanisms underlying head and neck squamous cell carcinoma (HNSCC) is vital for the development of effective treatment strategies. Deubiquitinating enzymes (DUBs), which regulate ubiquitin‐dependent
Externí odkaz:
https://doaj.org/article/b8b785699a9a4837967dc25a36773d99
Redefining GBA gene structure unveils the ability of Cap-independent, IRES-dependent gene regulation
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
The cell type-specific expression of the glucocerebrosidase gene, associated with the lysosomal storage disorder called Gaucher disease, is linked to cis- and trans-regulatory transcriptional and translational mechanisms.
Externí odkaz:
https://doaj.org/article/1513a9ca36b84fb28407adbc1675daa8
Autor:
Ayako Tanimura, Keiko Miyoshi, Taigo Horiguchi, Hiroko Hagita, Koichi Fujisawa, Takafumi Noma
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 5, Pp 1936-1950 (2018)
Background/Aims: Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) are involved in hematopoietic differentiation. However, the mechanistic linkage between ER stress/UPR and hematopoietic differentiation remains unclear. Methods: W
Externí odkaz:
https://doaj.org/article/0878eb4c17334e71a3a9f8cd1d35a457
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89916 (2014)
Adenine nucleotide dynamics in the mitochondrial intermembrane space (IMS) play a key role in oxidative phosphorylation. In a previous study, Drosophila adenylate kinase isozyme 2 (Dak2) knockout was reported to cause developmental lethality at the l
Externí odkaz:
https://doaj.org/article/f100b59695574dcdb9531289c5de37ad
Publikováno v:
International journal of molecular sciences. 24(1)
Ubiquitination and deubiquitination are two popular ways for the post-translational modification of proteins. These two modifications affect intracellular localization, stability, and function of target proteins. The process of deubiquitination is in
Autor:
Taigo Horiguchi, Ayako Tanimura, Keiko Miyoshi, Hiroko Hagita, Hisanori Minami, Takafumi Noma
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 16089
Mitochondrial ATP production plays an important role in most cellular activities, including growth and differentiation. Previously we reported that Adenylate kinase 2 (AK2) is the main ADP supplier in the mitochondrial intermembrane space in hematopo
Gene-expression profile reveals the genetic and acquired phenotypes of hyperactive mutant SPORTS rat
Autor:
Hiroko Hagita, Taigo Horiguchi, Yumiko Miyatake, Ayako Tanimura, Hiroshi Sakaue, Takafumi Noma, Keiko Miyoshi
Publikováno v:
The Journal of Medical Investigation. 67(1-2):51-61
Spontaneously Running Tokushima Shikoku (SPORTS) rat is a hyperactive rat strain. However, the causative mutation of this phenotype has not yet been identified. To investigate the molecular basis for the unique phenotype of SPORTS rats, we examined g
Autor:
Takafumi Noma, Taigo Horiguchi, Ayako Tanimura, Hiroko Hagita, Dian Yosi Arinawati, Keiko Miyoshi
Publikováno v:
Journal of Bioscience and Bioengineering. 125:479-489
The conventional two-dimensional (2D) in vitro culture system is frequently used to analyze the gene expression with or without extracellular signals. However, the cells derived from primary culture and cell lines frequently deviate the gene expressi
Autor:
Takafumi Noma, Hiroko Hagita, Keiko Miyoshi, Taigo Horiguchi, Ayako Tanimura, Koichi Fujisawa
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 5, Pp 1936-1950 (2018)
Background/Aims: Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) are involved in hematopoietic differentiation. However, the mechanistic linkage between ER stress/UPR and hematopoietic differentiation remains unclear. Methods: W
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
Oral mucosa is a useful material for regeneration therapy with the advantages of its accessibility and versatility regardless of age and gender. However, little is known about the molecular characteristics of oral mucosa. Here we report the first com