Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Taide Wang"'
Autor:
Adam Southon, Sophia J Luikinga, Andre L. Samson, Aida Viden, James M. Murphy, Brittany Cuic, Samantha K. Barton, Nirma D Perera, Doris Tomas, Catriona McLean, Taide Wang, Bradley J. Turner, Ashley I. Bush
Publikováno v:
Cell Death Differ
Amyotrophic lateral sclerosis (ALS) is caused by selective degeneration of motor neurons in the brain and spinal cord; however, the primary cell death pathway(s) mediating motor neuron demise remain elusive. We recently established that necroptosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808298cfc4ea679a0fadfc715a2d9cf2
https://europepmc.org/articles/PMC9177596/
https://europepmc.org/articles/PMC9177596/
Autor:
Alistair Govier-Cole, Valeria Rytova, Taide Wang, Samantha K. Barton, Aida Viden, Matthew C. Kiernan, Marius Rosier, Lucy M. Palmer, Samuel A. Mills, Bradley J. Turner, Catriona McLean, Brittany Cuic, Elvan Djouma, Mouna Haidar, Doris Tomas, Sophia J Luikinga, Steve Vucic, David G. Gonsalvez
Amyotrophic lateral sclerosis (ALS) is a progressive fatal disorder caused by degeneration of motor neurons in the cortex and spinal cord. The origin of ALS in the central nervous system is unclear, however cortical hyperexcitability appears as an ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a5957a6e9d50603befc23eacb9a5662
https://doi.org/10.1101/2021.08.13.456320
https://doi.org/10.1101/2021.08.13.456320
Autor:
Taide Wang, Shane D. Hellyer, Kathy Sengmany, Sabine Albold, Arthur Christopoulos, Lauren T. May, Karen J. Gregory, P. Jeffrey Conn, Katie Leach
Publikováno v:
Neuropharmacology
Allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGlu(5)) have been proposed as potential therapies for various CNS disorders. These ligands bind to sites distinct from the orthosteric (or endogenous) ligand, often with improve
Autor:
Doris Tomas, Wayne Cawthorne, Nayomi Wanniarachchillage, James M. Murphy, Brittany Cuic, Nirma D Perera, Mathew D. F. Chiam, Andre L. Samson, Bradley J. Turner, Eric N. Valor, Taide Wang
Publikováno v:
Cell Death Differ
Motor neuron degeneration in amyotrophic lateral sclerosis (ALS) is proposed to occur by necroptosis, an inflammatory form of regulated cell death. Prior studies implicated necroptosis in ALS based on accumulation of necroptotic markers in affected t
Autor:
Lauren T. May, Sabine Albold, Taide Wang, Amy N. Y. Chen, Karen J. Gregory, Katie Leach, Shane D. Hellyer
Publikováno v:
Molecular Pharmacology. 93:504-514
Numerous positive and negative allosteric modulators (PAMs and NAMs) of Class C G protein-coupled receptors (GPCRs) have been developed as valuable preclinical pharmacological tools and therapeutic agents. While many Class C GPCR allosteric modulator
Publikováno v:
IBRO Reports. 6:S292
Autor:
Shane D, Hellyer, Sabine, Albold, Taide, Wang, Amy N Y, Chen, Lauren T, May, Katie, Leach, Karen J, Gregory
Publikováno v:
Molecular pharmacology. 93(5)
Numerous positive and negative allosteric modulators (PAMs and NAMs) of class C G protein-coupled receptors (GPCRs) have been developed as valuable preclinical pharmacologic tools and therapeutic agents. Although many class C GPCR allosteric modulato