Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Taichi Hamanaka"'
Publikováno v:
Virology. 486:63-70
The prion strain-specific mechanism by which normal prion protein is converted to abnormal prion protein remains largely unknown. This study found that insect juvenile hormone III reduced abnormal prion protein levels only in cells infected with the
Autor:
Taichi Hamanaka, Hiroshi Kurahashi, Katsumi Doh-ura, Ayumi Oguma, Keiko Nishizawa, Kenta Teruya, Yuji Sakasegawa
Publikováno v:
Biochemistry and Biophysics Reports
No remedies for prion disease have been established, and the conversion of normal to abnormal prion protein, a key event in prion disease, is still unclear. Here we found that substances in beetle grub hemolymph, after they were browned by aging for
Autor:
Katsumi Doh-ura, Masahiro Wakao, Taichi Hamanaka, Kenta Teruya, Yasuo Suda, Masaki Sato, Keiko Nishizawa, Yuji Sakasegawa, Yukino Funayama
Publikováno v:
Biochemical and Biophysical Research Communications. 460:989-995
Glycosaminoglycans reportedly play important roles in prion formation, but because of their structural complexity, the chemical structures affecting prion formation have not been fully evaluated. Here, we compared two types of low molecular weight he
Autor:
Kenta Teruya, Hiroshi Kurahashi, Yuji Sakasegawa, Keiko Nishizawa, Katsumi Doh-ura, Ayumi Oguma, Taichi Hamanaka, Suehiro Sakaguchi, Hideyuki Hara
Publikováno v:
Journal of virology. 91(6)
Prion diseases are progressive fatal neurodegenerative illnesses caused by the accumulation of transmissible abnormal prion protein (PrP). To find treatments for prion diseases, we searched for substances from natural resources that inhibit abnormal
Autor:
Taichi Hamanaka, Katsumi Doh-ura, Tomohiro Kimura, Akihiro Ohmoto, Yuji Sakasegawa, Takao Ando
Publikováno v:
Biochemical and Biophysical Research Communications. 405:285-290
Protein-bound polysaccharide K (PSK) is a clinical immunotherapeutic agent that exhibits various biological activities, including anti-tumor and anti-microbial effects. In the present study, we report on the anti-prion activity of PSK. It inhibited t
Autor:
Taichi Hamanaka1, Keiko Nishizawa1, Yuji Sakasegawa1, Ayumi Oguma1, Kenta Teruya1, Hiroshi Kurahashi1, Hideyuki Hara2, Suehiro Sakaguchi2, Katsumi Doh-ura1 doh-ura@med.tohoku.ac.jp
Publikováno v:
Journal of Virology. Mar2017, Vol. 91 Issue 6, p1-19. 19p.