A genomic sequence of the type II-A clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated system in Mycoplasma salivarium strain ATCC 29803

Autor: Harumi Mizuki, Yu Shimoyama, Taichi Ishikawa, Minoru Sasaki

Publikováno v: Journal of Oral Microbiology, Vol 14, Iss 1 (2022)

Introduction Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated systems are RNA-mediated adaptive immune systems that actagainst invading genetic elements such as phages or plasmids. CRISPR/Cas systems exist in nearl

Externí odkaz: https://doaj.org/article/9486595a1e4945209fa281c4ffb6c9ca

Oral and Gut Microbial Dysbiosis and Non-alcoholic Fatty Liver Disease: The Central Role of Porphyromonas gingivalis

Autor: Ting Wang, Taichi Ishikawa, Minoru Sasaki, Toshimi Chiba

Publikováno v: Frontiers in Medicine, Vol 9 (2022)

Gut microbiota play many important roles, such as the regulation of immunity and barrier function in the intestine, and are crucial for maintaining homeostasis in living organisms. The disruption in microbiota is called dysbiosis, which has been asso

Externí odkaz: https://doaj.org/article/537c2fda88594a359fa71306494d59f7

The Role of Lactic Acid on Wound Healing, Cell Growth, Cell Cycle Kinetics, and Gene Expression of Cultured Junctional Epithelium Cells in the Pathophysiology of Periodontal Disease

Autor: Taichi Ishikawa, Daisuke Sasaki, Ryo Aizawa, Matsuo Yamamoto, Takashi Yaegashi, Tarou Irié, Minoru Sasaki

Publikováno v: Pathogens, Vol 10, Iss 11, p 1507 (2021)

Lactic acid (LA) is short-chain fatty acid, such as butyric acid and propionic acid, that is produced as a metabolite of lactic acid bacteria, including periodontopathic bacteria. These short-chain fatty acids have positive effects on human health bu

Externí odkaz: https://doaj.org/article/19db7b3c362c487583d9b0d1515d0392

Effect of Butyric Acid in the Proliferation and Migration of Junctional Epithelium in the Progression of Periodontitis: An In Vitro Study

Autor: Taichi Ishikawa, Daisuke Sasaki, Ryo Aizawa, Yu Shimoyama, Matsuo Yamamoto, Tarou Irié, Minoru Sasaki

Publikováno v: Dentistry Journal, Vol 9, Iss 4, p 44 (2021)

Purpose: To elucidate the effects of butyric acid (BA), a metabolite of bacteria involved in periodontitis, and a possible enhancer of the junctional epithelial cells. Methods: A murine junctional epithelial cell line, JE-1, was used to assess the ef

Externí odkaz: https://doaj.org/article/26392438fea942bb9400b69882454bce

Learning DOM Trees of Web Pages by Subpath Kernel and Detecting Fake e-Commerce Sites

Autor: Yu-Lu Liu, Taichi Ishikawa, Kilho Shin, David Lawrence Shepard

Publikováno v: Machine Learning and Knowledge Extraction, Vol 3, Iss 6, Pp 95-122 (2021)
Machine Learning and Knowledge Extraction
Volume 3
Issue 1
Pages 6-122

The subpath kernel is a class of positive definite kernels defined over trees, which has the following advantages for the purposes of classification, regression and clustering: it can be incorporated into a variety of powerful kernel machines includi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7476ca0ac4dcfd021c6aed1b15b7b3d2
https://www.mdpi.com/2504-4990/3/1/6