Výsledky vyhledávání - "Taichang Yuan"

Akademický článek

Lactation defect in a widely used MMTV-Cre transgenic line of mice.

Autor: Taichang Yuan, Yongping Wang, Lily Pao, Steve M Anderson, Haihua Gu

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e19233 (2011)

MMTV-Cre mouse lines have played important roles in our understanding about the functions of numerous genes in mouse mammary epithelial cells during mammary gland development and tumorigenesis. However, numerous studies have not included MMTV-Cre mic

Externí odkaz: https://doaj.org/article/9ffa6991991140edbe33d66d1d195079

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Shp1 positively regulates EGFR signaling by controlling EGFR protein expression in mammary epithelial cells

Autor: Licai He, Xusheng Xiong, Zenghui Fang, Taichang Yuan, Zhuanyun Du, Hua Ma, Hongzhi Li, Haihua Gu, Hongwei Gao

Publikováno v: Biochemical and Biophysical Research Communications. 488:439-444

SH2-domain containing protein tyrosine phosphatase 1 (Shp1/PTPN6) is mainly expressed in hematopoietic cells and acts a negative signaling regulator. Although Shp1 is also expressed in epithelial cells, the function of shp1 in normal epithelial is st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5932a5c563032c8502e3ec6a8ddb3e43
https://doi.org/10.1016/j.bbrc.2017.04.072

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Akademický článek

3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-γ-dependent and mediated by the caspase-3-dependent apoptotic pathway.

Autor: Yuanyuan Xiao¹, Taichang Yuan¹, Wenqi Yao¹, Kan Liao¹ kliao@sibs.ac.cn

Publikováno v: FEBS Journal. Feb2010, Vol. 277 Issue 3, p687-696. 10p. 6 Graphs.

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Protein-tyrosine Phosphatase PTPN9 Negatively Regulates ErbB2 and Epidermal Growth Factor Receptor Signaling in Breast Cancer Cells

Autor: Haihua Gu, Yongping Wang, Zhizhuang Joe Zhao, Taichang Yuan

Publikováno v: Journal of Biological Chemistry. 285:14861-14870

ErbB family of the receptor protein-tyrosine kinase plays an important role in the progression of human cancers including breast cancer. Finding protein-tyrosine phosphatase (PTPs) that can specifically regulate the function of ErbB should help desig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a7f032e62b053ee424ac88fc832dcc
https://doi.org/10.1074/jbc.m109.099879

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3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-γ-dependent and mediated by the caspase-3-dependent apoptotic pathway

Autor: Wenqi Yao, Taichang Yuan, Yuanyuan Xiao, Kan Liao

Publikováno v: FEBS Journal. 277:687-696

Although thiazolidinediones (TZDs) are potent promoters of adipogenesis in the preadipocyte, they induce apoptosis in several other cell types, such as cancer cells, endothelial cells and T-lymphocytes. In this study, we investigated the proapoptotic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56119c573b3d5131c3d810d7abcfd843
https://doi.org/10.1111/j.1742-4658.2009.07514.x

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Glut-4 is translocated to both caveolae and non-caveolar lipid rafts, but is partially internalized through caveolae in insulin-stimulated adipocytes

Autor: Taichang Yuan, Shangyu Hong, Kan Liao, Yao Yao

Publikováno v: Cell Research. 17:772-782

Caveolae and non-caveolar lipid rafts are two types of membrane lipid microdomains that play important roles in insulin-stimulated glucose uptake in adipocytes. In order to ascertain their specific functions in this process, caveolae were ablated by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107a723b6d19b04c10fe10a4d6d2992b
https://doi.org/10.1038/cr.2007.73

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Lactation defect in a widely used MMTV-Cre transgenic line of mice

Autor: Yongping Wang, Lily Pao, Taichang Yuan, Steve Anderson, Haihua Gu

Publikováno v: PLoS ONE
PLoS ONE, Vol 6, Iss 4, p e19233 (2011)

Background MMTV-Cre mouse lines have played important roles in our understanding about the functions of numerous genes in mouse mammary epithelial cells during mammary gland development and tumorigenesis. However, numerous studies have not included M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4889b3f1bb3355a5dedb89445220bce1
https://pubmed.ncbi.nlm.nih.gov/21559430

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3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-gamma-dependent and mediated by the caspase-3-dependent apoptotic pathway

Autor: Yuanyuan, Xiao, Taichang, Yuan, Wenqi, Yao, Kan, Liao

Publikováno v: The FEBS journal. 277(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ac1b8c0dcf3b72feae819f1c54355977
https://pubmed.ncbi.nlm.nih.gov/20050918

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The differential protein and lipid compositions of noncaveolar lipid microdomains and caveolae

Autor: Taichang Yuan, Kan Liao, Shangyu Hong, Hu Zhou, Yao Yao, Rong Zeng

Publikováno v: Cell research. 19(4)

Morphologically, caveolae and lipid rafts are two different membrane structures. They are often reported to share similar lipid and protein compositions, and are considered to be two subtypes of membrane lipid microdomains. By modifying sucrose densi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253b23f06cea948338e3c7fe877790d5
https://pubmed.ncbi.nlm.nih.gov/19255590

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Akademický článek

Protein-tyrosine Phosphatase PTPN9 Negatively Regulates ErbB2 and Epidermal Growth Factor Receptor Signaling in Breast Cancer Cells.

Autor: Taichang Yuan¹, Yongping Wang¹, Zhizhuang J. Zhao², Haihua Gu¹ haihua.gu@ucdenver.edu

Publikováno v: Journal of Biological Chemistry. 5/14/2010, Vol. 285 Issue 20, p14861-14870. 10p. 4 Diagrams, 3 Graphs.

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