Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Tai-Wing Wu"'
Publikováno v:
Life Sciences. 71:2249-2255
We observed that 3-methyl-1-1phenyl-2-pyrazolin-5-one (MCI-186), a newly-developed free radical scavenger, attenuated necrosis in the in vivo rabbit hearts upon reperfusion after prolonged ischemia. In rabbits undergoing 1 hour ligation of the anteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897e363a962d5ff4c4eb4ae63f2cb061
https://doi.org/10.1016/s0024-3205(02)01965-3
https://doi.org/10.1016/s0024-3205(02)01965-3
Publikováno v:
Life Sciences. 67:2387-2392
The bioactivity of 3-methyl-1-phenyl-pyrazolin-5-one (MCI-186) was examined based on histochemical changes in drastic global ischemic rat brains. Rats with mean arterial blood pressure reduction were subjected to 60 min cerebral ischemia/80 min reper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5dc3242d13f833f882dbc9b3ba4a872
https://doi.org/10.1016/s0024-3205(00)00824-9
https://doi.org/10.1016/s0024-3205(00)00824-9
Publikováno v:
Life Sciences. 67:91-99
The co-incubation of morin hydrate with either doxorubicin or mitomycin C could minimize the toxicity of these anti-tumor drugs on cardiovascular cells, such as red blood cells, human umbilical vein endothelial cells (ECV304) and primary mouse cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d06848e582a2f9750978143bfdbfeeeb
https://doi.org/10.1016/s0024-3205(00)00605-6
https://doi.org/10.1016/s0024-3205(00)00605-6
Publikováno v:
Biochemistry and Cell Biology. 75:717-720
Oxygen-derived free radicals are known to injure the endothelium of aorta in diverse disorders. In this study we compared the cytoprotective effects of three flavonoids against oxyradical damage to porcine aortic endothelial cells in vitro. Cultured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebb792bdbf1c06e16cc00ce9a7c50d6
https://doi.org/10.1139/o97-062
https://doi.org/10.1139/o97-062
Publikováno v:
Chemotherapy. 42:199-205
We demonstrated, for the first time, that the flavonoid purpurogallin (PPG) at 0.2-0.5 mM inhibits DNA synthesis of murine fibrosarcoma L-929 and human U-87 MG glioblastoma cells in vitro. In the human U-87 MG glioblastoma cell experiments, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc60632ab97d1ca302c6d8aff0f538b
https://doi.org/10.1159/000239442
https://doi.org/10.1159/000239442
Publikováno v:
Life Sciences. 58:PL17-PL22
We demonstrated that the flavonoid morin hydrate at 75-100 microM protects against the oxidation of low density lipoprotein (LDL) by free radicals produced by 2,2'-azo-bis(2-amidinopropane) dihydrochloride. Morin hydrate reduces the relative electrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc571b3c84ef60be25ca9d57aaa7229c
https://doi.org/10.1016/0024-3205(95)02270-8
https://doi.org/10.1016/0024-3205(95)02270-8
Autor:
Norman Camerman, Arthur A. Grey, Kwok-Pui Fung, Andrew Hempel, Jun Wu, Ling-Hua Zeng, Tai-Wing Wu
Publikováno v:
Biochemical Pharmacology. 49:537-543
Morin hydrate is a bioactive pigment found in yellow Brazil wood. Recently, we reported that morin hydrate prolongs the survival of three types of cells from the human circulatory system against oxyradicals generated in vitro. The protection excels t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8cf078bec5c2a400aec7e5456b2ca5
https://doi.org/10.1016/0006-2952(94)00446-s
https://doi.org/10.1016/0006-2952(94)00446-s
Publikováno v:
Life Sciences. 54:PL477-PL481
Oxidative modification of human low density lipoprotein (LDL) has been implicated in plaque formation in blood vessels leading to atherogenesis. Conversely, there is increasing evidence that prevention of LDL oxidation reduces the incidence of corona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0610e7e74cc028891f83f63235eb633
https://doi.org/10.1016/0024-3205(94)90140-6
https://doi.org/10.1016/0024-3205(94)90140-6
Publikováno v:
Life Sciences. 55:PL351-PL357
Cultured rat glomerular mesangial cells were damaged when exposed to oxyradicals generated either from xanthine oxidase plus hypoxanthine, or by superoxide radicals formed from menadione. Morin hydrate is an antioxidant extracted from yellow Brazil w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1f05c712a5871d6b6751d4c658ca65
https://doi.org/10.1016/0024-3205(94)00760-8
https://doi.org/10.1016/0024-3205(94)00760-8
Publikováno v:
Cardiovascular Research. 27:736-739
Objective: The aim was to determine if lactosylphenyl Trolox could improve myocardial resistance to ischaemia and reperfusion. Lactosylphenyl Trolox is derived by coupling p-aminophenyl-β-D-lactopyranoside to Trolox. Trolox, a polar analogue of vita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120306b7911127e6b2b145e6d6c6a3c4
https://doi.org/10.1093/cvr/27.5.736
https://doi.org/10.1093/cvr/27.5.736