Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tai Youn Rhim"'
Publikováno v:
Carbohydrate Polymers. 92:57-62
Chitosan-based nanoparticles have been widely used as a carrier for gene delivery due to their low toxicity and the positively charged amino groups in chitosan. In this study, we hypothesized that introduction of nonaarginine to chitosan could improv
Autor:
Jin Hyun Kang, Hun Soo Chang, Tai Youn Rhim, Byung Soo Kim, Il Yup Chung, Do Jin Kim, Seol Kyung Lee, Tae Gi Uhm, Choon-Sik Park
Publikováno v:
Experimental & Molecular Medicine
DNA methylation may regulate gene expression by restricting the access of transcription factors. We have previously demonstrated that GATA-1 regulates the transcription of the CCR3 gene by dynamically interacting with both positively and negatively a
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797(10):1687-1695
Vacuolar (H+)-ATPases, also called V-ATPases, are ATP-driven proton pumps that are highly phylogenetically conserved. Early biochemical and cell biological studies have revealed many details of the molecular mechanism of proton pumping and of the str
Autor:
Ji-Hee Kwon, Young Mok Lee, Choon-Sik Park, Hajime Takizawa, Mi-Hyun Ahn, Shin-Hwa Lee, Tai Youn Rhim, An-Soo Jang, Hyun-Mi Song
Publikováno v:
Environmental Toxicology. 23:110-116
Background: Chitinase may play a role in regulating allergic diseases. Objective: We studied the role of chitinase in a mouse model exposed to diesel exhaust particles (DEP). Mice were exposed to intranasal DEP (0.6 mg/mL) for 5 days and challenged w
Publikováno v:
Molecular & Cellular Proteomics. 6:56-63
Inhalation of particulate matter aggravates respiratory symptoms in patients with chronic airway diseases, but the mechanisms underlying this response remain poorly understood. We used a proteomics approach to examine this phenomenon. Treatment of ep
Autor:
Choon-Sik Park, June-Hyuk Lee, Sung Woo Park, Tai Youn Rhim, Ji-Yeon Lee, An-Soo Jang, Ho Young Kim, Eun-Suk Koh, Hee Kyoung Chang
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 173:729-735
ADAM33 has been identified as a novel asthma susceptibility gene in genomewide screening and association studies. High-level expression in smooth muscles and fibroblasts suggests that ADAM33 plays a role in airway remodeling in patients with asthma.T
Autor:
Hun Soo Chang, Choon-Sik Park, Hyoung Doo Shin, June-Hyuk Lee, Tai Youn Rhim, Sung Woo Park, An-Soo Jang, Ji-Won Min
Publikováno v:
Journal of Human Genetics. 50:118-123
Chemokine (C-C motif) ligand 24 (CCL24, eotaxin-2) is a CC chemokine that recruits and activates cells bearing the CC chemokine receptor 3, which play a major role in asthma. Previously, we observed a significant association between a single nucleoti
Autor:
Choon-Sik Park, Yun Sung Choi, Tai Youn Rhim, Eun Nam Choi, Hun Soo Chang, Il Yup Chung, Jungsun Kim
Publikováno v:
International Archives of Allergy and Immunology. 136:295-302
Background: Th2 cytokines play pivotal roles in allergic inflammation, including eosinophilia, and their actions are antagonized by Th1 cytokines, conferring them therapeutic potential. Methods: In this study, we examined the ability of a number of c
Autor:
Soung Soo Kim, Ilo Jou, Jooyoung Ryu, Hankyoung Pyo, Tae Hyong Kim, Byung-Kwan Jin, Eun-Hye Joe, Kyoung-Jin Min, Seung-Up Kim, Tai Youn Rhim
Publikováno v:
The Journal of Immunology. 168:5805-5810
Microglia, the major immune effector cells in the CNS, become activated when the brain suffers injury. In this study, we observed that prothrombin, a zymogen of thrombin, induced NO release and mRNA expression of inducible NO synthase, IL-1β, and TN
Publikováno v:
Angiogenesis. 5:191-201
Prothrombin, a protein involved in blood coagulation, is a plasma glycoprotein composed of the Gla domain, two adjacent kringle domains, and a serine protease domain. Kringles are triple-disulfide-loop folding domains, which are found in several othe