Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Tai Rao"'
Autor:
Na Liu, Jinfeng Liu, Binjie Zheng, Xiangchang Zeng, Zixin Ye, Xinyi Huang, Wenhui Liu, Yating Liu, Qing Fang, Lulu Chen, Tai Rao, Dongsheng Ouyang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114400- (2023)
Isoniazid (INH) is a highly effective single and/or combined first-line anti-tuberculosis (anti-TB) therapy drug, and the hepatotoxicity greatly limits its clinical application. INH-induced liver injury (INH-DILI) is a typical immune-mediated idiosyn
Externí odkaz:
https://doaj.org/article/f45c5f0804b846a4a7098f8daaf915c4
Autor:
Ying Xu, Song-xia Zhang, Jing Guo, Li-jie Chen, Yu-ligh Liou, Tai Rao, Jing-bo Peng, Ying Guo, Wei-hua Huang, Zhi-rong Tan, Dong-sheng Ou-yang, Hong-hao Zhou, Wei Zhang, Yao Chen
Publikováno v:
Journal of Analytical Methods in Chemistry, Vol 2022 (2022)
Mice are the most frequently used animals in pharmacokinetic studies; however, collecting series of blood samples from mice is difficult because of their small sizes and tiny vessels. In addition, due to the small sample size, it is problematic to pe
Externí odkaz:
https://doaj.org/article/6ec2c148e4344cab83125a7f4e3be213
Autor:
Xinyi Huang, Chao Li, Chaopeng Li, Zhenyu Li, Xiaohui Li, Jianwei Liao, Tai Rao, Lulu Chen, Lichen Gao, Dongsheng Ouyang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Depression disorder is one of the most serious mental illnesses in the world. Escitalopram is the essential first-line medication for depression disorder. It is the substrate of hepatic cytochrome P450 (CYP) enzyme CYP2C19 with high polymorphism. The
Externí odkaz:
https://doaj.org/article/31f309e3bf0e4de282d1e7b127fc4ecb
Autor:
Yan Liang, Yuanyuan Zhou, Jingwei Zhang, Tai Rao, Lijun Zhou, Rong Xing, Qian Wang, Hanxu Fu, Kun Hao, Lin Xie, Guangji Wang
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98717 (2014)
Phytochemical-mediated alterations in P-glycoprotein (P-gp) activity may result in herb-drug interactions by altering drug pharmacokinetics. Shengmai-san, a traditional Chinese herbal medicine composed by Panax Ginseng, Ophiopogon Japonicus, and Schi
Externí odkaz:
https://doaj.org/article/16aa8c08456544749eec7a932960073b
Akademický článek
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Publikováno v:
Chinese Journal of Natural Medicines. 18:500-507
Gut microbiota dysbiosis is a risk factor for colorectal cancer (CRC) in inflammatory bowel disease (IBD). In this study, the effects of Panax notoginseng saponins (PNS) on colitis-associated CRC progression were evaluated on an azoxymethane (AOM)/de
Autor:
Wenhui Meng, Yao Chen, Tong Liu, Zhirong Tan, Jingbo Peng, Jiwei Guo, Zhaoqian Liu, Tai Rao, Jing Yu, Feng Peng
Publikováno v:
Expert Review of Proteomics. 17:233-242
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic appro
Autor:
Jing Guo, Ying Xu, Li-Jie Chen, Song-xia Zhang, Tai Rao, Jing-bo Peng, Ying Guo, Zhi-rong Tan, Dong-sheng Ou-yang, Xiao-ping Chen, Yu-Ligh Liou, Wei Zhang, Yao Chen
Background: Pharmacokinetic variability in disease state is common in clinical practice, but the underlying mechanism remains unclear. We aim to investigate the effects of gut microbiota and host Cyp450s on pharmacokinetic variability in mice with no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d373b5e75fce0e937e7ffbd56cc8c253
https://doi.org/10.21203/rs.3.rs-729728/v1
https://doi.org/10.21203/rs.3.rs-729728/v1
Autor:
Chong Ma, Xiaowei Liu, Ying Guo, Ruidong Li, Helen J. Renaud, Tai Rao, Cui Tang, Ting Zhou, Zhi-Rong Tan, Wei Lin, Qiongni Zhu
Publikováno v:
OncoTargets and Therapy. 12:6001-6012
Purpose Imprinted genes are often identified as key players in the etiology and prognosis of many tumors; however, the role they play in colon cancer remains unclear. Along with the development of big data analysis came the discovery of a wealth of g
Publikováno v:
Chinese Journal of Natural Medicines. 17:231-240
Panax notoginseng saponins (PNS) are the major components of Panax notoginseng, with multiple pharmacological activities but poor oral bioavailability. PNS could be metabolized by gut microbiota in vitro, while the exact role of gut microbiota of PNS