Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tahsin N Khan"'
Autor:
Jossef F Osborn, Samuel J Hobbs, Jana L Mooster, Tahsin N Khan, Augustus M Kilgore, Jake C Harbour, Jeffrey C Nolz
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007633 (2019)
Memory CD8+ T cells in the circulation rapidly infiltrate non-lymphoid tissues following infection and provide protective immunity in an antigen-specific manner. However, the subsequent fate of memory CD8+ T cells after entering non-lymphoid tissues
Externí odkaz:
https://doaj.org/article/3d83680066fd4304be459b61fd72a3bb
Autor:
Akira Nabeshima, Tahsin N. Khan, Taishi Sato, Zhenyu Yao, Eemeli Jämsen, Emmanuel Gibon, Stuart B. Goodman, Tzuhua Lin, Jukka Pajarinen
Publikováno v:
J Biomed Mater Res A
Periprosthetic osteolysis remains as a major complication of total joint replacement surgery. Modulation of macrophage polarization with interleukin-4 (IL-4) has emerged as an effective means to limit wear particle-induced osteolysis. The aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d389684f6a72bad30bfffaa24887f8
https://doi.org/10.1002/jbm.a.37142
https://doi.org/10.1002/jbm.a.37142
Publikováno v:
The Journal of Experimental Medicine
CD8+ T cells activated during viral infection migrate to infected skin in an antigen-independent manner. Local recognition of antigens drives the differentiation into Trm CD8+ T cells.
Tissue-resident memory (Trm) CD8+ T cells are functionally d
Tissue-resident memory (Trm) CD8+ T cells are functionally d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d30c8256c75c81c1cfa2db43232454
http://europepmc.org/articles/PMC4886364
http://europepmc.org/articles/PMC4886364
Autor:
Zhenyu Yao, Jhih-Fong Huang, Jukka Pajarinen, Masahiro Maruyama, Yusuke Kohno, Karthik Nathan, Monica Romero-Lopez, Tzuhua Lin, Stuart B. Goodman, Tahsin N. Khan
Background Mesenchymal stromal cell (MSC)–based therapy has great potential to modulate chronic inflammation and enhance tissue regeneration. Crosstalk between MSC-lineage cells and polarized macrophages is critical for bone formation and remodelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81753936d02cee8a10c50be8947d2eea
https://europepmc.org/articles/PMC6379084/
https://europepmc.org/articles/PMC6379084/
Autor:
Eric B. Wong, Shwetank, Phillip P. Domeier, Stephanie L. Schell, Zia Ur Rahman, Melinda J. Elias, Chetna Soni, Aron E. Lukacher, Timothy K. Cooper, Tahsin N. Khan
Publikováno v:
Journal of Autoimmunity. 63:31-46
The inhibitory IgG Fc receptor (FcγRIIB) deficiency and 129 strain-derived signaling lymphocyte activation molecules (129-SLAMs) are proposed to contribute to the lupus phenotype in FcγRIIB-deficient mice generated using 129 ES cells and backcrosse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032e1d906c67a7b20ff929f5b779e903
https://doi.org/10.1016/j.jaut.2015.06.011
https://doi.org/10.1016/j.jaut.2015.06.011
Publikováno v:
The Journal of Immunology. 190:1433-1446
Mer receptor tyrosine kinase is a member of the Tyro-3/Axl/Mer (TAM) subfamily of receptor tyrosine kinases, and its expression on phagocytes facilitates their clearance of apoptotic cells (ACs). Mer expression in germinal centers (GCs) occurs predom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e46eb9cc077b8e0dc4d6c68590dec1
https://doi.org/10.4049/jimmunol.1200824
https://doi.org/10.4049/jimmunol.1200824
Autor:
Phillip P. Domeier, Zia Ur Rahman, Sathi Babu Chodisetti, Thomas Abraham, Melinda J. Elias, Edward K. Wakeland, Chetna Soni, Shwetank, Tahsin N. Khan, Eric B. Wong, Nisha Limaye, Alice Y. Chan
Publikováno v:
Journal of Immunology, Vol. 194, no. 9, p. 4130-4143 (2015)
Signaling lymphocyte activation molecules (SLAMs) play an integral role in immune regulation. Polymorphisms in the SLAM family receptors are implicated in human and mouse model of lupus disease. The lupus-associated, somatically mutated, and class-sw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ec0e5bd687e058274fcc679092eefe
https://europepmc.org/articles/PMC4402266/
https://europepmc.org/articles/PMC4402266/
Autor:
Shizuo Akira, Eric B. Wong, Phillip P. Domeier, Chetna Soni, Zia Ur Rahman, Tahsin N. Khan, Takashi Satoh
Spontaneous germinal center (Spt-GC) B cells and follicular helper T cells generate high-affinity autoantibodies that are involved in the development of systemic lupus erythematosus. TLRs play a pivotal role in systemic lupus erythematosus pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3877b5ff948db9c7d42920d9d99cfa
https://europepmc.org/articles/PMC4201954/
https://europepmc.org/articles/PMC4201954/
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 189(12)
C57BL/6 (B6) mice carrying the Sle1b sublocus (named B6.Sle1b), which harbors the lupus-associated NZM2410/NZW SLAM family genes, produce antinuclear Abs (ANAs). However, the role and mechanism(s) involved in the alteration of the germinal center (GC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261dc9f5f7d74586a5d4dde7445e2d63
https://pubmed.ncbi.nlm.nih.gov/23144494
https://pubmed.ncbi.nlm.nih.gov/23144494
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 185(10)
Germinal centers (GCs) are specialized microenvironments that generate high-affinity Ab-forming cells (AFCs) and memory B cells. Many B cells undergo apoptosis during B cell clonal selection in GCs. Although the factors that regulate the AFC and GC r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c371c0b9fcc13359f520393a6b22c327
https://pubmed.ncbi.nlm.nih.gov/20952679
https://pubmed.ncbi.nlm.nih.gov/20952679