Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Tahseen H, Nasti"'
Autor:
Peng Li, Haydn Kissick, Rebecca C Obeng, Tahseen H Nasti, Christiane S Eberhardt, Rafi Ahmed, Zhengjia Chen, Warren J Leonard, Suresh S Ramalingam, Andreas Wieland, Annapaola Mariniello, Jeffrey M Switchenko, Kylee Martens, Daniel Y Chang, Donald McGuire, Candace Daugherty, Yuzi Zhang, Rathi Pillai, Alice O Kamphorst
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective Immune checkpoint inhibitors (ICI) that block the programmed cell death 1 (PD-1) pathway have shown promise with limited benefit. We and others have shown in small patient cohorts that an early proliferative CD8 T-cell response in the blood
Externí odkaz:
https://doaj.org/article/4cc0e384a52945fa895729f71406f6ed
Autor:
Rajesh M. Valanparambil, Lilin Lai, Margaret A. Johns, Meredith Davis-Gardner, Susanne L. Linderman, Tarrant Oliver McPherson, Andres Chang, Akil Akhtar, Estefany L. Bocangel Gamarra, Hayley Matia, Ashley A. McCook-Veal, Jeffrey Switchenko, Tahseen H. Nasti, Felicia Green, Manpreet Saini, Andreas Wieland, Benjamin A. Pinsky, Daniel Solis, Madhav V. Dhodapkar, Jennifer Carlisle, Suresh Ramalingam, Rafi Ahmed, Mehul S. Suthar
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-4 (2023)
Abstract This study reports that most patients with NSCLC had a significant increase in the nAb response to the currently circulating Omicron variants after bivalent booster vaccination and had Ab titers comparable to healthy participants. Interestin
Externí odkaz:
https://doaj.org/article/f3270d0b4e494f458d929fb6e04f135c
Autor:
David Lawson, Zachary S Buchwald, Tahseen H Nasti, Judong Lee, Christiane S Eberhardt, Se Jin Im, Walter Curran, Rafi Ahmed, Mohammad K Khan, Andreas Wieland
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Radiotherapy (RT) has been shown to stimulate an antitumor immune response in irradiated tumors as well as unirradiated distant sites (abscopal effect). Previous studies have demonstrated a role for the tumor-draining lymph node (LN) in me
Externí odkaz:
https://doaj.org/article/7c7d8658ae3d4abb9d68605872b992f4
Autor:
Rajesh M. Valanparambil, Jennifer Carlisle, Susanne L. Linderman, Akil Akthar, Ralph Linwood Millett, Lilin Lai, Andres Chang, Ashley A. McCook-Veal, Jeffrey Switchenko, Tahseen H. Nasti, Manpreet Saini, Andreas Wieland, Kelly E. Manning, Madison Ellis, Kathryn M. Moore, Stephanie L. Foster, Katharine Floyd, Meredith E. Davis-Gardner, Venkata-Viswanadh Edara, Mit Patel, Conor Steur, Ajay K. Nooka, Felicia Green, Margaret A. Johns, Fiona O'Brein, Uma Shanmugasundaram, Veronika I. Zarnitsyna, Hasan Ahmed, Lindsay E. Nyhoff, Grace Mantus, Michael Garett, Srilatha Edupuganti, Madhusmita Behra, Rustom Antia, Jens Wrammert, Mehul S. Suthar, Madhav V. Dhodapkar, Suresh Ramalingam, Rafi Ahmed
Publikováno v:
Journal of Clinical Oncology. 40:3808-3816
PURPOSE To examine COVID-19 mRNA vaccine–induced binding and neutralizing antibody responses in patients with non–small-cell lung cancer (NSCLC) to SARS-CoV-2 614D (wild type [WT]) strain and variants of concern after the primary 2-dose and boost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14d319511fd2013c1714abacd9af343c
https://doi.org/10.1200/jco.21.02986
https://doi.org/10.1200/jco.21.02986
Publikováno v:
Vaccines, Vol 9, Iss 12, p 1396 (2021)
The use of immune checkpoint inhibitors (ICI) has substantially increased the overall survival of cancer patients and has revolutionized the therapeutic situation in oncology. However, not all patients and cancer types respond to ICI, or become resis
Externí odkaz:
https://doaj.org/article/7276d1c26d624fee9984a5207bdfa689
Autor:
Jay C. Shiao, BS MSc, Nathan Bowers, BS PhD, Tahseen H. Nasti, PhD, Faisal Khosa, MD, Mohammad K. Khan, MD PhD
Publikováno v:
Advances in Radiation Oncology, Vol 2, Iss 3, Pp 398-402 (2017)
Externí odkaz:
https://doaj.org/article/ce14850f6089449599881609a7d9e081
Autor:
Zachary S. Buchwald, Jacob Wynne, Tahseen H. Nasti, Simeng Zhu, Waleed F. Mourad, Weisi Yan, Seema Gupta, Samir N. Khleif, Mohammad K. Khan
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The combination of radiation and immunotherapy is currently an exciting avenue of pre-clinical and clinical investigation. The synergy between these two treatment modalities has the potential to expand the role of radiation from a purely local therap
Externí odkaz:
https://doaj.org/article/18529fbf63614edfa15b79c8420eb224
Autor:
Maria Cardenas, Mihir R. Patel, John Sidney, Alessandro Sette, Dong M. Shin, Mary Carrington, Tahseen H. Nasti, Haydn T. Kissick, Rafi Ahmed, Xu Wang, Zhuo Georgia Chen, Nataliya Prokhnevska, Andreas Wieland, Rebecca C. Obeng, Christopher C. Griffith, Se Jin Im, Nabil F. Saba, Christiane S Eberhardt
Publikováno v:
Nature
T cells are important in tumour immunity but a better understanding is needed of the differentiation of antigen-specific T cells in human cancer1,2. Here we studied CD8 T cells in patients with human papillomavirus (HPV)-positive head and neck cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c82df87829409a7da3e01e474182c51
https://doi.org/10.1038/s41586-021-03862-z
https://doi.org/10.1038/s41586-021-03862-z
Autor:
Jeanne Kowalski, Milota Kaluzova, Andre J. Burnham, Daniel Pomeranz Krummel, Mario Medvedovic, Tahseen H. Nasti, Soma Sengupta, Mohammad K. Khan, Yichun Cao, Maxwell Xu, Jeffrey M. Switchenko, Johannes C. Melms, Andrew Jenkins, Dan Ionascu, James M. Cook, Laura Kallay, David H. Lawson, Guanguan Li, Taukir Ahmed, Debanjan Bhattacharya, Benjamin Izar
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 109:1040-1053
Purpose Most patients with metastatic melanoma show variable responses to radiation therapy and do not benefit from immune checkpoint inhibitors. Improved strategies for combination therapy that leverage potential benefits from radiation therapy and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e17b725a1ff9fc1519bdd3e966777143
https://doi.org/10.1016/j.ijrobp.2020.10.025
https://doi.org/10.1016/j.ijrobp.2020.10.025
Publikováno v:
Molecular Carcinogenesis. 60:60-70
Ultraviolet (UV) B irradiation of the skin induces acute inflammation, as characterized by erythema, edema, and immunosuppression, and is subsequently linked to the progression of skin cancer. Toll-like receptor 4 (TLR4), a component of innate immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15717867695294b8381b2d2e87460148
https://doi.org/10.1002/mc.23271
https://doi.org/10.1002/mc.23271