Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tahniyath Ara"'
Autor:
Leggy A. Arnold, Dana Pearson, Wen Z. Lynt, Premchendar Nandhikonda, Daniel D. Bikle, Nina Y. Yuan, R. Kiplin Guy, Tahniyath Ara, Athena M. Baranowski, Megan M. McCallum
Publikováno v:
Journal of Medicinal Chemistry. 55:4640-4651
The vitamin D receptor (VDR) is a nuclear hormone receptor that regulates cell proliferation, cell differentiation, and calcium homeostasis. The receptor is activated by vitamin D analogues that induce the disruption of VDR-corepressor binding and pr
Autor:
Kyu Kwang Kim, Katina Robison, Megan M. McCallum, Leggy A. Arnold, Thilo S. Lange, Rakesh K. Singh, Laurent Brard, Tahniyath Ara, Richard G. Moore
Publikováno v:
Gynecologic Oncology. 123:370-378
Objective In human trials calcitriol and its analogs displayed unacceptable systemic toxicities including hypercalcemia. This study was designed to evaluate a novel non-hypercalcemic vitamin-D derivative (MT19c) and its anticancer effects in cultured