Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tahereh Ziafazeli"'
Publikováno v:
Nutrition and Healthy Aging
BACKGROUND: Rpd3 is a conserved histone deacetylase that removes acetyl groups from lysine residues within histones and other proteins. Reduction or inhibition of Rpd3 extends longevity in yeast, worms, and flies. Previous studies in flies suggest an
Publikováno v:
Aging (Albany NY)
Histone deacetylase (HDAC) 1 regulates chromatin compaction and gene expression by removing acetyl groups from lysine residues within histones. HDAC1 affects a variety of processes including proliferation, development, metabolism, and cancer. Reducti
RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity
Publikováno v:
Aging (Albany NY)
Single-gene mutations that extend longevity have revealed regulatory pathways related to aging and longevity. RPD3 is a conserved histone deacetylase (Class I HDAC). Previously we showed that Drosophila rpd3 mutations increase longevity. Here we test
Publikováno v:
Experimental Gerontology. 46:391-396
The silent information regulator 2 (Sir2 or Sirtuin) family of proteins is highly conserved and has been implicated in the extension of longevity for several species. Mammalian Sirtuins have been shown to affect various aspects of physiology includin
Autor:
Fariba Kalantari, George N Tzimas, Lars Malmström, Patrick Auguste, Hojatollah Vali, Paulette Bioulac-Sage, Eric Chevet, Daniel Boismenu, Tahereh Ziafazeli
Publikováno v:
PROTEOMICS - CLINICAL APPLICATIONS. 3:307-321
To date the cellular and molecular mechanisms by which liver pathological calcifications occur and are regulated are poorly investigated. To study the mechanisms linked to their appearance, we performed a proteomics analysis of calcified liver sample
Publikováno v:
Zeitschrift für Naturforschung C. 60:938-942
Cancer patients’ responses to radiotherapy vary in severity. It has been suggested that it may be due to differences in intrinsic cellular radiosensitivity. Prediction of tissue reactions to radiotherapy would permit tailoring of dosage to each pat
Autor:
M. Constantine Samaan, Mohammad Imran Khan, Morgan D. Fullerton, Tahereh Ziafazeli, Gregory R. Steinberg, Sarah Sikkema, Katarina Marcinko
Publikováno v:
Physiological Reports
Obesity is associated with chronic low‐grade inflammation that involves infiltration of macrophages into metabolic organs such as skeletal muscle. Exercise enhances skeletal muscle insulin sensitivity independently of weight loss; but its role in r
Publikováno v:
International Journal of Low Radiation. 3:57
The comet assay was used to examine radiation workers who deal with radioisotopes such as iodine-125, iodine-131 and technetium-99m. In this study, lymphocytes from test and control donors were exposed to γ-radiation at 0, 1, 2, 4 and 6 Gy. A signif