Výsledky vyhledávání - "Tahera Ansari"

Akademický článek

Annexin A12–26 Treatment Improves Skin Heterologous Transplantation by Modulating Inflammation and Angiogenesis Processes

Autor: Jéssica Zani Lacerda, Carine Cristiane Drewes, Kallyne Kioko Oliveira Mimura, Caroline de Freitas Zanon, Tahera Ansari, Cristiane Damas Gil, Karin Vicente Greco, Sandra Helena Poliselli Farsky, Sonia Maria Oliani

Publikováno v: Frontiers in Pharmacology, Vol 9 (2018)

Skin graft successful depends on reduction of local inflammation evoked by the surgical lesion and efficient neovascularization to nutrition the graft. It has been shown that N-terminal portion of the Annexin A1 protein (AnxA1) with its anti-inflamma

Externí odkaz: https://doaj.org/article/e02acb5a07874834b7685eadd2a46212

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Antibacterial, remineralising and matrix metalloproteinase inhibiting scandium-doped phosphate glasses for treatment of dental caries

Autor: Susan M. Higham, Sabeel P. Valappil, Tahera Ansari, Rohan Sahdev, Ensanya A. Abou Neel, David M. Pickup, Lee Cooper, Emily Burden, EJ Miles, John V. Hanna

Publikováno v: Dental Materials

Objectives:\ud Antibiotic resistance is increasingly a growing global threat. This study aimed to investigate the potential use of newly developed scandium-doped phosphate-based glasses (Sc-PBGs) as an antibacterial and anticariogenic agent through c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d22c43f6d00b6cfa212154edca616bd
https://doi.org/10.1016/j.dental.2021.10.014

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Regeneration of the oesophageal muscle layer from oesophagus acellular matrix scaffold using adipose-derived stem cells

Autor: Fang Wang, Vladimir Zachar, Tahera Ansari, Jeppe Emmersen, Yasuko Maeda

Publikováno v: Wang, F, Maeda, Y, Zachar, V, Ansari, T & Emmersen, J 2018, ' Regeneration of the oesophageal muscle layer from oesophagus acellular matrix scaffold using adipose-derived stem cells ', Biochemical and Biophysical Research Communications, vol. 503, no. 1, pp. 271-277 . https://doi.org/10.1016/j.bbrc.2018.06.014

This study explored the feasibility of constructing a tissue engineered muscle layer in the oesophagus using oesophageal acellular matrix (OAM) scaffolds and human aortic smooth muscle cells (hASMCs) or human adipose-derived stem cells (hASCs). The s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5ce50deb558a296a67a445146ee4c9
https://doi.org/10.1016/j.bbrc.2018.06.014

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Development and Characterization of a Porcine Liver Scaffold

Autor: Karin Vicente Greco, Irene Obiri-Yeboa, Murali Somasundaram, Aaron Southgate, Paul Sibbons, Brian R. Davidson, Lubinda Mbundi, Adedamola Olayanju, Lauren Grace Jones, Tahera Ansari

Publikováno v: Stem cells and development. 29(5)

The growing number of patients requiring liver transplantation for chronic liver disease cannot be currently met due to a shortage in donor tissue. As such, alternative tissue engineering approaches combining the use of acellular biological scaffolds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865aed406bfeb896a0312b3020d337df
https://pubmed.ncbi.nlm.nih.gov/31854227

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Application of porcine gastrointestinal organoid units as a potential in vitro tool for drug discovery and development

Autor: Lauren Grace Jones, Adedamola Olayanju, Karin Vicente Greco, Christopher E. Goldring, Tahera Ansari

Publikováno v: Journal of Applied Toxicology. 39:4-15

The gastrointestinal tract (GI) is a crucial part of the body for growth and development and its dysregulation can lead to several diseases with detrimental effects. Most of these diseases lack effective treatment, occurring as a result of inappropri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edb0b81742265a8a58a5cf2aa32e12c7
https://doi.org/10.1002/jat.3641

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Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms

Publikováno v: Pridgeon, C S, Schlott, C, Wong, M W, Heringa, M B, Heckel, T, Leedale, J, Launay, L, Gryshkova, V, Przyborski, S, Bearon, R N, Wilkinson, E L, Ansari, T, Greenman, J, Hendriks, D F G, Gibbs, S, Sidaway, J, Sison-Young, R L, Walker, P, Cross, M J, Park, B K & Goldring, C E P 2018, ' Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms ', Archives of Toxicology, vol. 92, no. 2, pp. 557-569 . https://doi.org/10.1007/s00204-018-2152-9
Archives of Toxicology

The development of improved, innovative models for the detection of toxicity of drugs, chemicals, or chemicals in cosmetics is crucial to efficiently bring new products safely to market in a cost-effective and timely manner. In addition, improvement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abac4eb357d91a6ac35143bd8f1341eb
https://doi.org/10.1007/s00204-018-2152-9

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A comparison of tracheal scaffold strategies for pediatric transplantation in a rabbit model

Autor: Peggy Lange, Colin R. Butler, Nicholas Hamilton, Claire Crowley, Margot Den Hondt, Martin A. Birchall, Elizabeth F. Maughan, Sam M. Janes, Luca Urbani, Robert E. Hynds, Martin J. Elliott, Paolo De Coppi, Tahera Ansari, Gui Zhen Teoh

Publikováno v: The Laryngoscope. 127:E449-E457

Objectives/hypothesis Despite surgical advances, childhood tracheal stenosis is associated with high morbidity and mortality. Various tracheal scaffold strategies have been developed as the basis for bioengineered substitutes, but there is no consens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ad7a780bcbab3a9e34abe95993461d4
https://doi.org/10.1002/lary.26611

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Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine

Publikováno v: Stem Cells Translational Medicine

Tracheal replacement for the treatment of end-stage airway disease remains an elusive goal. The use of tissue-engineered tracheae in compassionate use cases suggests that such an approach is a viable option. Here, a stem cell-seeded, decellularized t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077a958ee57accd29cadfa0b9ad93613
https://doi.org/10.1002/sctm.16-0443

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Characterization of a biologically derived rabbit tracheal scaffold

Autor: Tahera Ansari, Martin A. Birchall, Paul Sibbons, P. Lange, H. Shah

Publikováno v: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 105:2126-2135

There is a clinical need to provide replacement tracheal tissue for the pediatric population affected by congenital defects, as current surgical solutions are not universally applicable. A potential solution is to use tissue engineered scaffold as th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8011a8b0a77b2d5ad1aaaeab9f8e3137
https://doi.org/10.1002/jbm.b.33741

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Development of a novel hybrid bioactive hydrogel for future clinical applications

Autor: Nicholas R. English, Judith J Roether, Karin Vicente Greco, Honglei Huang, Rutger J. Ploeg, Tahera Ansari, Aldo R. Boccaccini, Lydia Francis

Publikováno v: Journal of biomaterials applications. 33(3)

Three-dimensional hydrogels are ideal for tissue engineering applications due to their structural integrity and similarity to native soft tissues; however, they can lack mechanical stability. Our objective was to develop a bioactive and mechanically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f09f637f0edd898051dd9403632b98
https://pubmed.ncbi.nlm.nih.gov/30223736

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