Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Taher Al-Tweigeri"'
Autor:
Syed S. Islam, Taher Al-Tweigeri, Layla Al-Harbi, Shafat Ujjahan, Maha Al-Mozaini, Asma Tulbah, Abdelilah Aboussekhra
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Breast cancer (BC) patient who receives chemotherapy for an extended length of time may experience profound repercussions in terms of metastases and clinical outcomes due to the involvement of the epithelial-to-mesenchymal transition (EMT) m
Externí odkaz:
https://doaj.org/article/36a646056f724073be5011d02cb36d13
Autor:
Taher Al-Tweigeri, Noura N. AlRaouji, Asma Tulbah, Maria Arafah, Mouad Aboussekhra, Falah Al-Mohanna, Ahmed Mostafa Gad, Abdelmonneim M. Eldali, Tusneem A. Elhassan, Abdelilah Aboussekhra
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-15 (2022)
Abstract Background Locally advanced breast cancer (LABC), the most aggressive form of the disease, is a serious threat for women's health worldwide. The AU-rich RNA-binding factor 1 (AUF1) promotes the formation of chemo-resistant breast cancer stem
Externí odkaz:
https://doaj.org/article/fdfaf012f7d645afbcc26f3df30413d9
Autor:
Hazem Ghebeh, Adher Al-Sayed, Riham Eiada, Leilani Cabangon, Dahish Ajarim, Kausar Suleman, Asma Tulbah, Taher Al-Tweigeri
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Therapeutic anti-PD-L1 antibodies are safe as a monotherapy, albeit with minimal efficacy in triple-negative breast cancer (TNBC). This trial aimed to test the safety and efficacy of Durvalumab and Paclitaxel in metastatic TNBC. In this open
Externí odkaz:
https://doaj.org/article/4082da344ce44ce6b8b8a7859e11152b
Autor:
Layla A. Al-Kharashi, Asma Tulbah, Maria Arafah, Abdelmonneim M. Eldali, Taher Al-Tweigeri, Abdelilah Aboussekhra
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundActive breast cancer-associated fibroblasts (CAFs) play a leading role in breast carcinogenesis through promoting angiogenesis and resistance to therapy. Consequently, these active stromal cells have significant influence on patient outcome
Externí odkaz:
https://doaj.org/article/f60d4db3c00e44c5922321049ef9a011
Autor:
Mysoon M. Al-Ansari, Maher Al-Saif, Maria Arafah, Abdelmonneim M. Eldali, Asma Tulbah, Taher Al-Tweigeri, Abdelhabib Semlali, Khalid S. Khabar, Abdelilah Aboussekhra
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background Most breast cancer-associated fibroblasts (CAFs) are active and important cancer-promoting cells, with significant impact on patient prognosis. Therefore, we investigated here the role of the protein kinase ATR in breast stromal f
Externí odkaz:
https://doaj.org/article/3ba1da8a49ab492aadff73a319d53652
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 366 (2022)
Triple-negative breast cancers (HER2−, ER−, PR−) continue to present a unique treatment challenge and carry unfavorable prognoses. The elucidation of novel therapeutic targets has necessitated the re-evaluation of stratification approaches to b
Externí odkaz:
https://doaj.org/article/668836c27ad549e8a612a5bf4bc2e125
Autor:
Hazem Ghebeh, Fatmah A. Mansour, Dilek Colak, Akram A. Alfuraydi, Amal A. Al-Thubiti, Dorota Monies, Monther Al-Alwan, Taher Al-Tweigeri, Asma Tulbah
Publikováno v:
Antibodies, Vol 10, Iss 3, p 24 (2021)
Purpose: Response to anti-PD-L1/PD-1 immunotherapy correlates with PD-L1 expression in breast cancer. However, the prevalence of PD-L1 positive breast cancer is variable, which could be due to differences in the population/cohort of patients tested o
Externí odkaz:
https://doaj.org/article/e671fedb9b4a4539aec0b4ca03702f49
Publikováno v:
Genes, Vol 12, Iss 4, p 549 (2021)
Resistance to therapy is a persistent problem that leads to mortality in breast cancer, particularly triple-negative breast cancer (TNBC). MiRNAs have become a focus of investigation as tissue-specific regulators of gene networks related to drug resi
Externí odkaz:
https://doaj.org/article/52843f5ee1934667a14fad356518becb
Publikováno v:
Immunotherapy. 14(4)
Introduction: There is evidence for an association between peripheral blood eosinophil count (PBEC) and response to cancer immunotherapy; however, such data is limited in metastatic triple-negative breast cancer (mTNBC). Patients & methods: This repo
Autor:
Mysoon M. Al-Ansari, Siti-Fauziah Hendrayani, Asma Tulbah, Taher Al-Tweigeri, Afaf I. Shehata, Abdelilah Aboussekhra
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 12, Pp 1269-1277 (2012)
Stromal fibroblasts, the most abundant and probably the most active cellular component of breast cancer-associated stroma, become active and promote angiogenesis through paracrine effects. However, it still unclear how these processes are regulated.
Externí odkaz:
https://doaj.org/article/fd74f4c576e44dc099df666b9f874945