Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Taha I. Huda"'
Publikováno v:
Exploration of Immunology, Vol 3, Iss 6, Pp 598-603 (2023)
Exome and RNAseq files prepared from blood samples can be mined for adaptive immune receptor recombinations and thus for the complementarity determining region-3 (CDR3) amino acid (AA) sequences, important for antigen binding. In this report, the T-c
Externí odkaz:
https://doaj.org/article/7bf74cc9add64d8088e2abe76fe4496c
Autor:
Monica Hsiang, Boris I. Chobrutskiy, Michael Diaz, Taha I. Huda, Stefan Creadore, Saif Zaman, Konrad J. Cios, Etienne C. Gozlan, George Blanck
Publikováno v:
Translational Oncology, Vol 14, Iss 6, Pp 101069- (2021)
Uterine cancer has been associated with a T-cell immune response that leads to increased survival. Therefore, we used several bioinformatics approaches to explore specific interactions between T-cell receptor (TCR) and tumor mutant peptide sequences.
Externí odkaz:
https://doaj.org/article/e1ec094967794abdb41c19add700e36b
Autor:
George Angelakakis, Karisa S. Serraneau, Vayda R. Barker, Blake M. Callahan, Wei Lue Tong, Saif Zaman, Taha I. Huda, George Blanck
Publikováno v:
International Journal of Immunogenetics. 50:41-47
Understanding racial disparities in cancer outcomes continues to be a challenge, with likely many factors at play, including socioeconomic factors and genetic polymorphisms impacting basic cellular and molecular functions. Additionally, it is possibl
Autor:
Rachel A. Eakins, Andrea Chobrutskiy, Jamie K. Teer, Dhruv N. Patel, Monica Hsiang, Taha I. Huda, Saif Zaman, Wade J. Sexton, Domenico Coppola, Shayan Falasiri, George Blanck, Boris I. Chobrutskiy
Publikováno v:
Molecular Immunology. 150:58-66
Cancer testis antigens have been of interest as possible targets for cancer immunotherapies. To better understand the opportunities for the use of such immunotherapy targets, we used a chemical complementarity scoring algorithm and an original web to
Autor:
Taha I. Huda, Michael J. Diaz, Etienne C. Gozlan, Andrea Chobrutskiy, Boris I. Chobrutskiy, George Blanck
Publikováno v:
Journal of Alzheimer's Disease. 88:619-629
Background: Despite the fact that only modest adaptive immune system related approaches to treating Alzheimer’s disease (AD) are available, an immunogenomics approach to the study of AD has not yet substantially advanced. Objective: Thus, we sought
Chemical features of melanoma tumor resident TRG CDR3s associated with better survival probabilities
Autor:
Deo Rei L. Agnila, Taha I. Huda, Rachel A. Eakins, Dhruv N. Patel, Monica Hsiang, Andrea Chobrutskiy, Boris I. Chobrutskiy, George Blanck
Publikováno v:
Melanoma Research.
Autor:
Jacob C Kinskey, Taha I Huda, Etienne C Gozlan, Jessica U Quach, Juan F Arturo, Andrea Chobrutskiy, Boris I Chobrutskiy, George Blanck
Publikováno v:
Carcinogenesis.
The association between pancreatic adenocarcinoma (PAAD) and the pancreatic microbiome is not fully understood, although bacteria may decrease the effectiveness of chemotherapy and lead to anti-apoptotic, pro-inflammatory-microenvironments. To better
Autor:
Jessica U. Quach, Michael J. Diaz, Taha I. Huda, Jacob C. Kinskey, Saif Zaman, John E. Desantis, Konrad J. Cios, George Blanck
Publikováno v:
Molecular Biotechnology.
Autor:
Mary F. Arndt, Etienne C. Gozlan, Michael J. Diaz, Saif Zaman, Moody M. Mihyu, George Blanck, Boris I. Chobrutskiy, Taha I. Huda
Publikováno v:
Leukemia & Lymphoma. 62:1711-1720
Multiple myeloma (MM) immunogenomics studies related to T-cell characterizations and involving large patient sets have been lacking, particularly in comparison to solid tumor types. Thus, we evaluated (i) HLA alleles, and (ii) T-Cell Receptor (TCR) V
Publikováno v:
Leukemialymphoma. 63(6)
In the diffuse large B-cell lymphoma (DLBCL) setting, we examined lymph node biopsy, T-cell receptor features, and the DLBLC patient human leukocyte antigen (HLA) alleles, to provide a basis for assessing survival distinctions represented by the Nati