Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tafheem Masudi"'
Autor:
Sanjay Kumar Sukumar, Vimala Antonydhason, Linnea Molander, Jawdat Sandakly, Malak Kleit, Ganesh Umapathy, Patricia Mendoza-Garcia, Tafheem Masudi, Andreas Schlosser, Dick R Nässel, Christian Wegener, Margret Shirinian, Ruth H Palmer
Publikováno v:
eLife, Vol 12 (2024)
Numerous roles for the Alk receptor tyrosine kinase have been described in Drosophila, including functions in the central nervous system (CNS), however the molecular details are poorly understood. To gain mechanistic insight, we employed Targeted Dam
Externí odkaz:
https://doaj.org/article/dfd88ed48fda4c0e92b123d709909f88
Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival
Autor:
Kathrin Pfeifer, Georg Wolfstetter, Vimala Anthonydhason, Tafheem Masudi, Badrul Arefin, Mats Bemark, Patricia Mendoza-Garcia, Ruth H. Palmer
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 8 (2022)
Activating anaplastic lymphoma kinase (ALK) receptor tyrosine kinase (RTK) mutations occur in pediatric neuroblastoma and are associated with poor prognosis. To study ALK-activating mutations in a genetically controllable system, we employed CRIPSR/C
Externí odkaz:
https://doaj.org/article/07bf718e76ba44b88c1bdc5f2a42c7cc
Autor:
Krithika Badarinath, Binita Dam, Sunny Kataria, Ravindra K. Zirmire, Rakesh Dey, Gaurav Kansagara, Johan Ajnabi, Akshay Hegde, Randhir Singh, Tafheem Masudi, Janani Sambath, Sasikala P. Sachithanandan, Prashant Kumar, Akash Gulyani, You-Wen He, Sudhir Krishna, Colin Jamora
Publikováno v:
Cell reports. 40(12)
Preservation of a small population of cancer stem cells (CSCs) within a heterogeneous carcinoma serves as a paradigm to understand how select cells in a tissue maintain their undifferentiated status. In both embryogenesis and cancer, Snail has been c
Autor:
Edries Y. Hajam, Colin Jamora, Surya Prakash Rao Batta, Debashish Danda, Renu George, Rakesh Dey, Toshiaki Kawakami, Krithika Badarinath, Tafheem Masudi, Peter A. Andreasen, Paul Mazhuvanchary Jacob, Neha Pincha, Rekha Samuel
Publikováno v:
Pincha, N, Hajam, E Y, Badarinath, K, Batta, S P R, Masudi, T, Dey, R, Andreasen, P, Kawakami, T, Samuel, R, George, R, Danda, D, Jacob, P M & Jamora, C 2018, ' PAI1 mediates fibroblast-mast cell interactions in skin fibrosis ', Journal of Clinical Investigation, vol. 128, no. 5, pp. 1807-1819 . https://doi.org/10.1172/JCI99088
Fibrosis is a prevalent pathological condition arising from the chronic activation of fibroblasts. This activation results from the extensive intercellular crosstalk mediated by both soluble factors and direct cell-cell connections. Prominent among t
Publikováno v:
Nature neuroscience. 19(6)
The dense reconstruction of neuronal circuits from volumetric electron microscopy (EM) data has the potential to uncover fundamental structure-function relationships in the brain. To address bottlenecks in the workflow of this emerging methodology, w