Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Taesam Kim"'
Autor:
Dong-Keon Lee, Taesam Kim, Junyoung Byeon, Minsik Park, Suji Kim, Joohwan Kim, Seunghwan Choi, Gihwan Lee, Chanin Park, Keun Woo Lee, Yong Jung Kwon, Jeong-Hyung Lee, Young-Guen Kwon, Young-Myeong Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The stress response protein REDD1 is regulates inflammation and energy metabolism. Here the authors report that global or adipocyte-specific deletion of REDD1 inhibits diet induced obesity, insulin resistance, liver steatosis and inflammation in mice
Externí odkaz:
https://doaj.org/article/e57f7aac4b8c46ada8ea086f107cc8d8
Autor:
Ji-Hee Kim, Ji-Yoon Kim, Minsik Park, Suji Kim, Taesam Kim, Joohwan Kim, Seunghwan Choi, Wonjin Park, Jong Yun Hwang, Jongseon Choe, Kwon-Soo Ha, Moo-Ho Won, Sungwoo Ryoo, Young-Guen Kwon, Young-Myeong Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 8, Pp 1298-1309 (2020)
Inflammatory vascular disease: miRNAs in blood vessel damage miRNA molecules that inhibit the activity of specific genes are implicated in a cellular control network involved in some of the damaging effects of inflammation on blood vessels. Researche
Externí odkaz:
https://doaj.org/article/93d9ce376df742148dda7e1ca8ed7afe
Autor:
Minsik Park, Seunghwan Choi, Suji Kim, Joohwan Kim, Dong-Keon Lee, Wonjin Park, Taesam Kim, Jiwon Jung, Jong Yun Hwang, Moo-Ho Won, Sungwoo Ryoo, Seung Goo Kang, Kwon-Soo Ha, Young-Guen Kwon, Young-Myeong Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 2, Pp 1-12 (2019)
Vascular disease: Small RNA as a possible culprit The overexpression of a microRNA molecule adversely affects the functioning of vascular smooth muscle cells (VSMCs) and may contribute to the development of artherosclerosis and preeclampsia. The inte
Externí odkaz:
https://doaj.org/article/2d17cb41f5d04569afe414a75c64d301
Autor:
Wonjin Park, Joohwan Kim, Seunghwan Choi, Taesam Kim, Minsik Park, Suji Kim, Ji-Chang You, Jeong Hun Kim, Kwon-Soo Ha, Jeong-Hyung Lee, Young-Guen Kwon, Young-Myeong Kim
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 134, Iss , Pp 111110- (2021)
Targeting the vascular endothelial growth factor (VEGF)/its receptor-2 (VEGFR-2) system has become a mainstay of treatment for many human diseases, including retinal diseases. We examined the therapeutic effect of recently developed N-acetylated Arg-
Externí odkaz:
https://doaj.org/article/c9a1c43f2dea4334a7218249e83763d1
Autor:
Suji Kim, Minsik Park, Ji-Yoon Kim, Taesam Kim, Jong Yun Hwang, Kwon-Soo Ha, Moo-Ho Won, Sungwoo Ryoo, Young-Guen Kwon, Young-Myeong Kim
Publikováno v:
Cells, Vol 9, Iss 9, p 2003 (2020)
Preeclampsia (PE) is a pregnancy-specific disorder associated with hypertension and proteinuria. Since there is no proven method to treat PE, early prediction and accurate diagnosis are essential for appropriate management of the disease. Thus, relia
Externí odkaz:
https://doaj.org/article/0d7b084943654c62b1327cd2312026de
Autor:
Suji Kim, Young-Guen Kwon, Kwon-Soo Ha, Taesam Kim, Minsik Park, Young-Myeong Kim, Jeong-Hyung Lee, Sung Hwan Cho, Wonjin Park, Moo Ho Won, Joohwan Kim
Publikováno v:
Experimental & Molecular Medicine
Low-dose metronomic chemotherapy (LDMC) inhibits tumor angiogenesis and growth by targeting tumor-associated endothelial cells, but the molecular mechanism has not been fully elucidated. Here, we examined the functional role of regulated in developme
Autor:
Dong-Keon Lee, Taesam Kim, Junyoung Byeon, Minsik Park, Suji Kim, Joohwan Kim, Seunghwan Choi, Gihwan Lee, Chanin Park, Keun Woo Lee, Yong Jung Kwon, Jeong-Hyung Lee, Young-Guen Kwon, Young-Myeong Kim
Publikováno v:
Nature communications. 13(1)
Regulated in development and DNA damage response 1 (REDD1) expression is upregulated in response to metabolic imbalance and obesity. However, its role in obesity-associated complications is unclear. Here, we demonstrate that the REDD1–NF-κB axis i
Autor:
Jung A. Yun, Seunghwan Choi, Kwon-Soo Ha, Dooil Jeoung, Yi Yong Baek, Minsik Park, Joohwan Kim, Taesam Kim, Ji Yoon Kim, Young Myeong Kim, Moo Ho Won, Young Guen Kwon, Hansoo Lee, Wonjin Park, Suji Kim
Publikováno v:
Molecular Pharmacology. 96:692-701
The tetrapeptide Arg-Leu-Tyr-Glu (RLYE), a vascular endothelial growth factor (VEGF) receptor-2 antagonist, has been used previously either alone or in combination with chemotherapeutic drugs for treating colorectal cancer in a mouse model. We analyz
Autor:
Jeong Hun Kim, Seunghwan Choi, Dong Hyun Jo, Minsik Park, Taesam Kim, Suji Kim, Ji Yoon Kim, Joohwan Kim, Jin Hyoung Kim, Yi Yong Baek, Moo Ho Won, Kwon-Soo Ha, Young Myeong Kim, Young Guen Kwon, Wonjin Park
Publikováno v:
Biomolecules & Therapeutics
Vascular endothelial growth factor (VEGF) plays a pivotal role in pathologic ocular neovascularization and vascular leakage via activation of VEGF receptor 2 (VEGFR2). This study was undertaken to evaluate the therapeutic mechanisms and effects of th
Autor:
Dong Keon Lee, Sungwoo Ryoo, Young Myeong Kim, Jiwon Jung, Taesam Kim, Suji Kim, Young Guen Kwon, Wonjin Park, Minsik Park, Seung Goo Kang, Kwon-Soo Ha, Moo Ho Won, Seunghwan Choi, Joohwan Kim, Jong Yun Hwang
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 2, Pp 1-12 (2019)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Vascular smooth muscle cells (VSMCs) play an important role in maintaining vascular function. Inflammation-mediated VSMC dysfunction leads to atherosclerotic intimal hyperplasia and preeclamptic hypertension; however, the underlying mechanisms are no