Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Taekyu Ha"'
Publikováno v:
Metals, Vol 14, Iss 8, p 877 (2024)
Open-cell type aluminum foams with various structural conditions and alloy compositions were manufactured using the replication casting process. The porosity of the foams ranged from 55% to 62%, with pore sizes of 0.7~1.0 mm, 1.0~2.0 mm, and 2.8~3.4
Externí odkaz:
https://doaj.org/article/3111103af4e74a9fb88d7d414b9de681
Publikováno v:
Crystals, Vol 14, Iss 3, p 290 (2024)
Trace elements such as boron (B) and zirconium (Zr) can increase creep resistance in nickel-based superalloys. This study investigates the change of microstructures on the grain boundary (GB) in phase-controlled nickel-based superalloys through the a
Externí odkaz:
https://doaj.org/article/7289ee2224074a69827cb56e6150d058
Publikováno v:
Metals, Vol 14, Iss 2, p 206 (2024)
Open-cell-type aluminum foam demonstrates excellent heat dissipation owing to interconnected pores. In this study, open-cell-type aluminum foams with various pore sizes and porosities were fabricated using the replication-casting process, which is a
Externí odkaz:
https://doaj.org/article/897ba01f19d645469fd20f499e0aa535
Autor:
Taekyu Ha, Michael DiPrima, Vishal Koparde, Parthav Jailwala, Hidetaka Ohnuki, Jing-Xin Feng, Murali Palangat, Daniel Larson, Giovanna Tosato
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 877-891 (2022)
Advances in gene therapy research have resulted in the successful development of new therapies for clinical use. Here, we explored a gene targeting approach to deplete ephrinB2 from colorectal cancer cells using an inducible lentiviral vector. Ephrin
Externí odkaz:
https://doaj.org/article/2dbdf16db27e41c0b007897ffdd92a3a
Autor:
Michael DiPrima, Dunrui Wang, Alix Tröster, Dragan Maric, Nekane Terrades‐Garcia, Taekyu Ha, Hyeongil Kwak, David Sanchez‐Martin, Denis Kudlinzki, Harald Schwalbe, Giovanna Tosato
Publikováno v:
Molecular Oncology, Vol 13, Iss 11, Pp 2441-2459 (2019)
Advanced colorectal carcinoma is currently incurable, and new therapies are urgently needed. We report that phosphotyrosine‐dependent Eph receptor signaling sustains colorectal carcinoma cell survival, thereby uncovering a survival pathway active i
Externí odkaz:
https://doaj.org/article/8f5f33f7824b4646a48a5bac962048a5
Autor:
Yuyi Wang, Michael DiPrima, Andy D. Tran, Jingxin Feng, Michael J. Kruhlak, Yanlin Yu, Ombretta Salvucci, Taekyu Ha, Hyeongil Kwak, Giovanna Tosato, Hidetaka Ohnuki, Dunrui Wang
Publikováno v:
EMBO Molecular Medicine
The tyrosine phosphatase SHP2 is oncogenic in cancers driven by receptor‐tyrosine‐kinases, and SHP2 inhibition reduces tumor growth. Here, we report that SHP2 is an essential promoter of endothelial cell survival and growth in the remodeling tumo
Autor:
Jingxin Feng, Yuyi Wang, Andy D. Tran, Diprima Michael J, Taekyu Ha, Giovanna Tosato, Hidetaka Ohnuki, Hyeongil Kwak, Ombretta Salvucci, Dunrui Wang, Michael J. Kruhlak
The tyrosine phosphatase SHP2 is oncogenic in cancers driven by receptor-tyrosine-kinases, and SHP2 inhibition reduces tumor growth. Here, we report that SHP2 is an essential promoter of endothelial cell survival and growth in the remodeling tumor va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12ee87ddb43d837b5c2f7f403c4855e4
https://doi.org/10.1101/2020.10.06.327882
https://doi.org/10.1101/2020.10.06.327882
Publikováno v:
Molecular carcinogenesis. 58(6)
Epithelial specific ETS-1 (ESE-1) belongs to the E26 transformation-specific transcription factor superfamily and is of great interest as a potential target for managing several types of cancer. Despite its clinical significance, the documented effec
Autor:
Yuyi Wang, Giovanna Tosato, Kenji Kabashima, Taekyu Ha, Dunrui Wang, Douglas R. Lowy, Atsushi Otsuka, Lisa Ritchey
Publikováno v:
Oncogene
Deleted in Liver Cancer 1 (DLC1) is a tumor suppressor gene deleted in many cancers, including angiosarcoma, an aggressive malignancy of endothelial cell derivation. DLC1-deficiency in primary endothelial cells causes the loss of cell contact inhibit
Publikováno v:
International Immunopharmacology. 35:287-293
Tolfenamic acid is one of the fenamic acid-derived non-steroid anti-inflammatory drugs (NSAIDs) and has been shown to exhibit anti-cancer activities in several types of cancer. Both mutations and aberrant expression of β-catenin are highly associate