Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Taekyoung Kwak"'
Autor:
Melinda Magna, Gyong Ha Hwang, Alec McIntosh, Katherine Drews-Elger, Masaru Takabatake, Adam Ikeda, Barbara J. Mera, Taekyoung Kwak, Philip Miller, Marc E. Lippman, Barry I. Hudson
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Triple-negative breast cancer (TNBC) is a highly aggressive and metastatic cancer subtype, which is generally untreatable once it metastasizes. We hypothesized that interfering with the Receptor for Advanced Glycation End-products (RAGE) sig
Externí odkaz:
https://doaj.org/article/f18933caaf174985b1637813da6ec4ae
Autor:
Melinda Magna, Gyong Ha Hwang, Alec McIntosh, Katherine Drews-Elger, Masaru Takabatake, Barbara Mera, Taekyoung Kwak, Philip Miller, Marc Lippman, Barry I. Hudson
Publikováno v:
Cancer Research. 83:P4-08
Background: Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype with a high metastatic rate. Despite significant advances in breast cancer therapeutics, due to the lack of specific therapeutic targets in TNBC, cytotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709d5e54bbe51a4dda9be2fcc2df8f3c
https://doi.org/10.1158/1538-7445.sabcs22-p4-08-10
https://doi.org/10.1158/1538-7445.sabcs22-p4-08-10
Autor:
Dmitry I. Gabrilovich, Amod A. Sarnaik, Meenhard Herlyn, Jeffrey S. Weber, Gao Zhang, Jiufeng Tan, Min Xiao, Vito W. Rebecca, Jane L. Messina, Michael Schell, Shari Pilon-Thomas, Valerie Moberg, Allison Richards, Laxminarasimha Donthireddy, Sergio Lavilla-Alonso, Taekyoung Kwak, Cigdem Atay
Purpose:BRAF and MEK inhibitors (BRAFi and MEKi) are actively used for the treatment of metastatic melanoma in patients with BRAFV600E mutation in their tumors. However, the development of resistance to BRAFi and MEKi remains a difficult clinical cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7b6419a819ee05fd6bc1d0bb7e5d9f
https://doi.org/10.1158/1078-0432.c.6528660
https://doi.org/10.1158/1078-0432.c.6528660
Autor:
Dmitry I. Gabrilovich, Amod A. Sarnaik, Meenhard Herlyn, Jeffrey S. Weber, Gao Zhang, Jiufeng Tan, Min Xiao, Vito W. Rebecca, Jane L. Messina, Michael Schell, Shari Pilon-Thomas, Valerie Moberg, Allison Richards, Laxminarasimha Donthireddy, Sergio Lavilla-Alonso, Taekyoung Kwak, Cigdem Atay
Supplemental Figure 1. Temporal regulation and the effect of combination of B-raf inhibitor on M6PR expression. Supplemental Figure 2. Effect of combination of B-raf and MEK inhibitors on M6PR expression. Supplemental Figure 3. WM35 cells resistant t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ac9e5a569075a46b74546c554e850a
https://doi.org/10.1158/1078-0432.22474029.v1
https://doi.org/10.1158/1078-0432.22474029.v1
Autor:
Laxminarasimha, Donthireddy, Prashanthi, Vonteddu, Tushar, Murthy, Taekyoung, Kwak, Rukiye-Nazan, Eraslan, Joseph R, Podojil, Adam, Elhofy, Michael T, Boyne, John J, Puisis, Filippo, Veglia, Surya S, Singh, Farokh, Dotiwala, Luis J, Montaner, Dmitry I, Gabrilovich
Publikováno v:
Journal of Cancer. 13:1933-1944
In this study, we evaluated the ability of negatively charged bio-degradable nanoparticles, ONP- 302, to inhibit tumor growth. Therapeutic treatment with ONP-302 in vivo resulted in a marked delay in tumor growth in three different syngeneic tumor mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c562ef1ef7d67bf1502c76f2830cae
https://doi.org/10.7150/jca.69338
https://doi.org/10.7150/jca.69338
Autor:
Tushar Murthy, Joseph Podojil, Taekyoung Kwak, Prashanthi Vonteddu, Adam Elhofy, Michael Boyne, John Puisis, Filippo Veglia, Surya Singh, Farokh Dotiwala, Luis Montaner, Dmitry Gabrilovich, Laxminarsimha Donthireddy, Rukiye-Nazan Eraslan
Publikováno v:
Journal of Clinical Oncology. 40:e14553-e14553
e14553 Background: The tumor microenvironment (TME) plays a crucial role in tumor growth and progression and has a significant influence on response to therapy. The TME consists of myeloid-derived cells, stroma (e.g. fibroblasts and extracellular mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa99ad3a4f75fd27bd45bb7f02733229
https://doi.org/10.1200/jco.2022.40.16_suppl.e14553
https://doi.org/10.1200/jco.2022.40.16_suppl.e14553