Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Taeko Yokochi"'
Autor:
Takako Koga, Tadatsugu Taniguchi, Miho Isobe, Taeko Yokochi, Britt Kern, Sunhwa Kim, Gerard Karsenty, Y. Eugene Chin, Hiroshi Takayanagi
Publikováno v:
Genes & Development. 17:1979-1991
Bone remodeling is central to maintaining the integrity of the skeletal system, wherein the developed bone is constantly renewed by the balanced action of osteoblastic bone formation and osteoclastic bone resorption. In the present study, we demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e882c67ef1e2f3f60e5a2cc6d865b5e
https://doi.org/10.1101/gad.1119303
https://doi.org/10.1101/gad.1119303
Autor:
Hiroshi Takayanagi, Hiroshi Nishina, Miho Isobe, Taeko Yokochi, Tadatsugu Taniguchi, Akio Saiura, Erwin F. Wagner, Sunhwa Kim, Hiroki Yoshida, Jun-ichiro Inoue, Tak W. Mak, Masashi Isshiki, Tatsuhiko Kodama, Takako Koga
Publikováno v:
Developmental Cell. 3:889-901
Signaling by RANKL is essential for terminal differentiation of monocytes/macrophages into osteoclasts. The TRAF6 and c-Fos signaling pathways both play important roles downstream of RANKL. We show here that RANKL selectively induces NFATc1 expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3043a4513fc55080d6138aef6ae0ff
https://doi.org/10.1016/s1534-5807(02)00369-6
https://doi.org/10.1016/s1534-5807(02)00369-6
Autor:
Erwin F. Wagner, Hiroshi Suzuki, Sunhwa Kim, Hiroshi Takayanagi, Kozo Nakamura, Hiromi Oda, Tomohiko Suzuki, Kojiro Sato, Taeko Yokochi, Nobutaka Ida, Tadatsugu Taniguchi, Koichi Matsuo
Publikováno v:
Nature. 416:744-749
Osteoclasts are cells of monocyte/macrophage origin that erode bone matrix: regulation of their differentiation is central to the understanding of the pathogenesis and treatment of bone diseases such as osteoporosis. Signalling by RANKL (receptor act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132e4b05e230ea9c8b7da89f860ea134
https://doi.org/10.1038/416744a
https://doi.org/10.1038/416744a
Autor:
Nobuyuki Tanaka, Ko Okumura, Hideo Yagita, Nobuhiko Kayagaki, Kojiro Sato, Kouetsu Ogasawara, Taeko Yokochi, Tadatsugu Taniguchi, Hiroshi Takayanagi, Kazuyoshi Takeda, Shigeaki Hida
Publikováno v:
European Journal of Immunology. 31:3138-3146
Natural killer (NK) cells play an important role in early defense against viral infection. The cytotoxic activity of NK cells is increased by interferon-alpha/beta (IFN-alpha/beta), produced en masse in virally infected cells. However, the mechanism(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73b787f93eea040e6c922b4b1ee2f048
https://doi.org/10.1002/1521-4141(200111)31:11<3138::aid-immu3138>3.0.co
https://doi.org/10.1002/1521-4141(200111)31:11<3138::aid-immu3138>3.0.co
Autor:
Tadatsugu Taniguchi, Yukiko Mitani, Akinori Takaoka, Nobuyuki Tanaka, Yukiko Kato, Sunhwa Kim, Taeko Yokochi
Publikováno v:
Genes to Cells. 6:631-640
Background Signalling cross talk provides a molecular basis for modulating a given signalling pathway by another, and it is often critical for regulating cellular responses elicited by cytokines. Previously, we reported on the critical role of the IF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c482c691ef666641eea3a95d844154c
https://doi.org/10.1046/j.1365-2443.2001.00448.x
https://doi.org/10.1046/j.1365-2443.2001.00448.x
Autor:
Katsushi Tokunaga, Kouetsu Ogasawara, Naoyuki Tsuchiya, Taeko Yokochi, Daisuke Sakurai, Akihiro Yamaguchi, Masatoshi Wakui, Yasuo Ikeda
Publikováno v:
Biochemical and Biophysical Research Communications. 282:200-206
Graft-versus-host reaction (GVHR) is a complex process initiated upon allorecognition. For detection of early molecular events in GVHR, we first assessed time courses with respect to symptoms and serum interferon (IFN)-gamma levels and then used the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27f244b7523eb83bae318f848ec2cca
https://doi.org/10.1006/bbrc.2001.4550
https://doi.org/10.1006/bbrc.2001.4550
Autor:
Kouetsu Ogasawara, Taeko Yokochi, Shigeaki Hida, Akinori Takaoka, Keiji Tanaka, Hiromi Oda, Kozo Nakamura, Kojiro Sato, Tadatsugu Taniguchi, Tomoki Chiba, Hiroshi Takayanagi, Shigeo Murata
Publikováno v:
Nature. 408:600-605
Bone resorption is regulated by the immune system, where T-cell expression of RANKL (receptor activator of nuclear factor (NF)-kappaB ligand), a member of the tumour-necrosis factor family that is essential for osteoclastogenesis, may contribute to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662572feb5d0dcdbe9987dcd75ecb897
https://doi.org/10.1038/35046102
https://doi.org/10.1038/35046102
Autor:
Yukiko Mitani, Akinori Takaoka, Tadatsugu Taniguchi, Taeko Yokochi, Nobuyuki Tanaka, Mitsuharu Sato, Shigeru Noguchi, Hirofumi Suemori
Publikováno v:
Science. 288:2357-2360
Definition of cellular responses to cytokines often involves cross-communication through their respective receptors. Here, signaling by interferon-gamma (IFN-gamma) is shown to depend on the IFN-alpha/beta receptor components. Although these IFNs tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3852d23989147d06224f18dd3b67167
https://doi.org/10.1126/science.288.5475.2357
https://doi.org/10.1126/science.288.5475.2357
Autor:
Nazli Azimi, Shinsuke Taki, Taeko Yokochi-Fukuda, Takeo Sato, Shigeaki Hida, Yutaka Tagaya, Thomas A. Waldmann, Kouetsu Ogasawara, Tadatsugu Taniguchi
Publikováno v:
Nature. 391:700-703
Natural killer (NK) cells are critical for both innate and adaptive immunity. The development of NK cells requires interactions between their progenitors and the bone-marrow microenvironment; however, little is known about the molecular nature of suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b9e3dd983fdd8895f81cfc685787e4
https://doi.org/10.1038/35636
https://doi.org/10.1038/35636
Autor:
Tomohiro Takasugi, Chris Schindler, Yasuo Kashiwazaki, Shigeru Noguchi, Mitsuharu Sato, Tadatsugu Taniguchi, Tohru Kimura, Masahito Matsumoto, Motoo Kitagawa, Robert D. Schreiber, Hisashi Harada, Rosemary Sok-Pin Tan, Yuzo Kadokawa, Taeko Yokochi
Publikováno v:
Genes to Cells. 1:995-1005
Background: Efficient production of interferons (IFNs) in virally infected cells is an essential aspect of the host defence. The transcription factor complex ISGF3 (IFN-stimulated gene factor 3) was originally identified as a critical mediator of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f57f8dd502b9025dff8e48015cae8d3
https://doi.org/10.1046/j.1365-2443.1996.870287.x
https://doi.org/10.1046/j.1365-2443.1996.870287.x