Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Taeko Nishiwaki‐Ohkawa"'
Autor:
Masakazu Nambo, Taeko Nishiwaki-Ohkawa, Akihiro Ito, Zachary T. Ariki, Yuka Ito, Yuuki Kato, Muhammad Yar, Jacky C. -H. Yim, Emily Kim, Elizabeth Sharkey, Keiko Kano, Emi Mishiro-Sato, Kosuke Okimura, Michiyo Maruyama, Wataru Ota, Yuko Furukawa, Tomoya Nakayama, Misato Kobayashi, Fumihiko Horio, Ayato Sato, Cathleen M. Crudden, Takashi Yoshimura
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-14 (2024)
Abstract Background Thyroid hormones (TH) regulate the basal metabolic rate through their receptors THRα and THRβ. TH activates lipid metabolism via THRβ, however, an excess amount of TH can lead to tachycardia, bone loss, and muscle wasting throu
Externí odkaz:
https://doaj.org/article/30f4577426754f67803518bc6b5bc019
Autor:
Apirada Padlom, Daisuke Ono, Rio Hamashima, Yuko Furukawa, Takashi Yoshimura, Taeko Nishiwaki-Ohkawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The circadian rhythm is a biological oscillation of physiological activities with a period of approximately 24 h, that is driven by a cell-autonomous oscillator called the circadian clock. The current model of the mammalian circadian clock i
Externí odkaz:
https://doaj.org/article/a04a9a2982724449921bdb41ed21e67d
Autor:
Manhui Zhang, Kohei Kobayashi, Haruki Atsumi, Yuma Katada, Yusuke Nakane, Junfeng Chen, Ryo Nagano, Naoya Kadofusa, Taeko Nishiwaki-Ohkawa, Naohiro Kon, Tsuyoshi Hirota, Ayato Sato, Toshiaki Makino, Takashi Yoshimura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Circadian rhythm is an approximately 24 h endogenous biological rhythm. Chronic disruption of the circadian clock leads to an increased risk of diabetes, cardiovascular disease, and cancer. Hence, it is important to develop circadian clock m
Externí odkaz:
https://doaj.org/article/1285ef65dde04431ac1b83145f05d5fd
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract At high latitudes, approximately 10% of people suffer from depression during the winter season, a phenomenon known as seasonal affective disorder (SAD). Shortened photoperiod and/or light intensity during winter season are risk factors for S
Externí odkaz:
https://doaj.org/article/05af824a25604e9e87ef75d939434cdb
Autor:
T Katherine Tamai, Yusuke Nakane, Wataru Ota, Akane Kobayashi, Masateru Ishiguro, Naoya Kadofusa, Keisuke Ikegami, Kazuhiro Yagita, Yasufumi Shigeyoshi, Masaki Sudo, Taeko Nishiwaki‐Ohkawa, Ayato Sato, Takashi Yoshimura
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 5, Pp 1-12 (2018)
Abstract Chronic circadian disruption due to shift work or frequent travel across time zones leads to jet‐lag and an increased risk of diabetes, cardiovascular disease, and cancer. The development of new pharmaceuticals to treat circadian disorders
Externí odkaz:
https://doaj.org/article/c7bdc79576a34ebc8a8689479d3981bc
Autor:
Keisuke Ikegami, Xiao-Hui Liao, Yuta Hoshino, Hiroko Ono, Wataru Ota, Yuka Ito, Taeko Nishiwaki-Ohkawa, Chihiro Sato, Ken Kitajima, Masayuki Iigo, Yasufumi Shigeyoshi, Masanobu Yamada, Yoshiharu Murata, Samuel Refetoff, Takashi Yoshimura
Publikováno v:
Cell Reports, Vol 9, Iss 3, Pp 801-809 (2014)
Thyroid-stimulating hormone (TSH; thyrotropin) is a glycoprotein secreted from the pituitary gland. Pars distalis-derived TSH (PD-TSH) stimulates the thyroid gland to produce thyroid hormones (THs), whereas pars tuberalis-derived TSH (PT-TSH) acts on
Externí odkaz:
https://doaj.org/article/2a84708a2084481ebaf4835222cbc177
Autor:
Yoshihiko Furuike, Atsushi Mukaiyama, Shin-ichi Koda, Damien Simon, Dongyan Ouyang, Kumiko Ito-Miwa, Shinji Saito, Eiki Yamashita, Taeko Nishiwaki-Ohkawa, Kazuki Terauchi, Takao Kondo, Shuji Akiyama
Publikováno v:
Proceedings of the National Academy of Sciences. 119
KaiC is a dual adenosine triphosphatase (ATPase), with one active site in its N-terminal domain and another in its C-terminal domain, that drives the circadian clock system of cyanobacteria through sophisticated coordination of the two sites. To eluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a264e6f86585d8198bde7f079f95a1c9
https://doi.org/10.1073/pnas.2119627119
https://doi.org/10.1073/pnas.2119627119
Autor:
Ayato Sato, Jiachen Shen, Andrew S. I. Loudon, Naoyuki Yamamoto, Akiko Shimada, Toshiya Nishimura, Toshitaka Nabeshima, Naoya Kadofusa, Kei Nakayama, Souta Minou, Minoru Tanaka, Nobuyuki Shiina, Tomoya Nakayama, Ai Shinomiya, Takashi Yoshimura, Ying-Jey Guh, Yuki Okushi, Taeko Nishiwaki-Ohkawa, Yusuke Nakane, Tsuyoshi Shimmura, T. Katherine Tamai, Yuko Furukawa, Kousuke Okimura
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance At high latitudes, about 10% of the population suffers from depression in winter. Although it has become a serious public health issue, its underlying mechanism remains unknown. Interestingly, animals also show depression-like behavior i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65153757bd73a2dc4a52ef20d08ffba
https://doi.org/10.1073/pnas.2000278117
https://doi.org/10.1073/pnas.2000278117
Publikováno v:
Microbial Cell, Vol 1, Iss 2, Pp 67-69 (2014)
Circadian rhythms, endogenous oscillations with periods of ~24 h, are found in many organisms, and they enhance fitness in alternating day/night environments. In cyanobacteria, three clock proteins, KaiA, KaiB, and KaiC, control the timekeeping mecha
Externí odkaz:
https://doaj.org/article/be1c06a694ec439898c2de15d6ab9236
Autor:
Shin-ichi Koda, Atsushi Mukaiyama, Damien Simon, Kumiko Ito-Miwa, Eiki Yamashita, Shinji Saito, Takao Kondo, Yoshihiko Furuike, Shuji Akiyama, Dongyan Ouyang, Taeko Nishiwaki-Ohkawa, Kazuki Terauchi
KaiC is a dual ATPase, with one active site in its N-terminal domain and another in its C-terminal domain, that drives the circadian clock system of cyanobacteria through sophisticated coordination of the two sites. To elucidate the coordination mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02be55b9a8396c581cb92d910cf5b0ef
https://doi.org/10.1101/2021.10.28.466029
https://doi.org/10.1101/2021.10.28.466029
