Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Taeko Hayakawa"'
Autor:
Koichi Fukunaga, Akihiko Yoshimura, Taeko Hayakawa, Kensuke Nakagawara, Makoto Ando, Tanakorn Srirat, Setsuko Mise-Omata, Minako Ito
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background Antitumor effect of chimeric antigen receptor (CAR)-T cells against solid tumors is limited due to various factors, such as low infiltration rate, poor expansion capacity, and exhaustion of T cells within the tumor. NR4A transcription fact
Externí odkaz:
https://doaj.org/article/3a8b2a7ada134def89e32c0e7021d8ba
Autor:
Tanakorn Srirat, Taeko Hayakawa, Setsuko Mise-Omata, Kensuke Nakagawara, Makoto Ando, Shigeyuki Shichino, Minako Ito, Akihiko Yoshimura
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113898- (2024)
Summary: T cell exhaustion impairs tumor immunity and contributes to resistance against immune checkpoint inhibitors. The nuclear receptor subfamily 4 group A (NR4a) family of nuclear receptors plays a crucial role in driving T cell exhaustion. In th
Externí odkaz:
https://doaj.org/article/a17174b04a184d3080522b8ca32dbab3
Autor:
Setsuko Mise-Omata, Makoto Ando, Tanakorn Srirat, Kensuke Nakagawara, Taeko Hayakawa, Mana Iizuka-Koga, Hiroshi Nishimasu, Osamu Nureki, Minako Ito, Akihiko Yoshimura
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112940- (2023)
Summary: Interleukin (IL)-6 is abundantly expressed in the tumor microenvironment and is associated with poor patient outcomes. Here, we demonstrate that the deletion of the suppressor of cytokine signaling 3 (SOCS3) in T cells potentiates anti-tumor
Externí odkaz:
https://doaj.org/article/3f935b2e37374fd2b1dbfe62d4e7a10b
Autor:
Tomoko Arai, Shinya Fujita, Hideaki Nakajima, Hiroshi Kobayashi, Takayuki Shimizu, Daiki Karigane, Tomonori Yaguchi, Naomi Kondoh, Hisako Katagiri, Keiyo Takubo, Rie Yamazaki, Kaori Yahagi, Yoko Yatabe, Shinichiro Okamoto, Masatoshi Sakurai, Mitsuru Murata, Jun Kato, Shinpei Tamaki, Takehiko Mori, Hidenori Kasahara, Maiko Matsushita, Takashi Sasaki, Taeko Hayakawa, Kouhei Shiroshita, Taku Kikuchi, Yutaka Kawakami, Nobuko Shimizu
Publikováno v:
Leukemia & Lymphoma. 62:679-687
Persistence of leukemic stem cells (LSCs) results in the recurrence of chronic myeloid leukemia (CML) after the administration of tyrosine kinase inhibitors (TKIs). Thus, the detection of minimal residual disease (MRD) with LSC potential can improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a32c0ccecea46015f17098f09967bab
https://doi.org/10.1080/10428194.2020.1837366
https://doi.org/10.1080/10428194.2020.1837366
Publikováno v:
Cancer Science
PD‐1/PD‐L1 immune checkpoint inhibitors are promising cancer immunotherapies however responses are still limited and the development of more effective combination immunotherapy is needed. We previously reported that STAT3 activation in cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bb57557985f9ba121705310bba3267
https://doi.org/10.1111/cas.14675
https://doi.org/10.1111/cas.14675
Autor:
Junichiro Miyazaki, Sunthamala Nuchsupha, Ryosuke Satomi, Kenta Nakamura, Shinobu Noji, Taeko Hayakawa, Hajime Kamijuku, Kinya Tsubota, Tomonari Kinoshita, Nobuo Tsukamoto, Toshiharu Sakurai, Hiroshi Nishio, Tomonori Yaguchi, Naoshi Kawamura, Yutaka Kawakami, Juri Sugiyama, Haruna Nagumo, Ikumi Katano, Boryana Popivanova, Tomonobu Fujita, Chie Kudo-Saito
Publikováno v:
Immunotherapy of Cancer ISBN: 9784431550303
Cancer immunotherapies utilizing tumor-specific T-cell responses, immune-checkpoint blockade, and T-cell-based adoptive cell therapy, have recently shown durable responses in advanced patients with various cancers. However, there are still cancer typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef52d4f2072799124265b06187c1c60
https://doi.org/10.1007/978-4-431-55031-0_24
https://doi.org/10.1007/978-4-431-55031-0_24
Autor:
Makoto Maemondo, Hiroyuki Mizuguchi, Toshikazu Nakamura, Yasuo Saijo, Toshihiro Nukiwa, Masahiko Kanehira, K Hoshino, Kunio Matsumoto, Hong Xin, Taeko Hayakawa
Publikováno v:
Cancer Gene Therapy. 14:894-903
Most advanced solid tumors metastasize to different organs. However, no gene therapy effective for multiple tumors has yet been developed. Since a unique characteristic of bone marrow-derived mesenchymal stem cells (MSCs) is that they migrate to tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2537d61c180d6079e868984e09d5e8b8
https://doi.org/10.1038/sj.cgt.7701079
https://doi.org/10.1038/sj.cgt.7701079
Autor:
Naoshi Kawamura, Tomonari Kinoshita, Toshiharu Sakurai, Kenta Nakamura, Kinya Tsubota, Hajime Kamijuku, Tomonori Yaguchi, Tracy Hsin-ju Liu, Sunthamala Nuchsupha, Hiroshi Nishio, Ryosuke Satomi, Nobuo Tsukamoto, Juri Sugiyama, Yutaka Kawakami, Gaku Ohmura, Boryana Popivanova, Junichiro Miyazaki, Taeko Hayakawa, Tomonobu Fujita, Chie Kudo-Saito, Li Qian
Publikováno v:
Resistance to Targeted Anti-Cancer Therapeutics ISBN: 9783319178066
Although cancer immunotherapy has recently demonstrated durable responses even in patients with advanced cancer, not all patients or cancer types respond to the therapy. Pretreatment immune status varies among cancer patients and is correlated with r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf2f2cc904831a4e7628191929384f3c
https://doi.org/10.1007/978-3-319-17807-3_13
https://doi.org/10.1007/978-3-319-17807-3_13
Autor:
Hiroshi Nishio, Haruna Nagumo, Junichiro Miyazaki, Hajime Kamijuku, Tomonori Yaguchi, Tomonobu Fujita, Yutaka Kawakami, Toshiharu Sakurai, Tracy Hsin-ju Liu, Sunthamala Nuchsupha, Li Qian, Ryosuke Satomi, Kinya Tsubota, Naoshi Kawamura, Nobuo Tsukamoto, Chie Kudo-Saito, Taeko Hayakawa, Tomonari Kinoshita, Boryana Popivanova, Kenta Nakamua, Gaku Ohmura, Juri Sugiyama
Publikováno v:
Inflammation and Immunity in Cancer ISBN: 9784431553267
Cancer immunotherapies, particularly immune-checkpoint blockade and T cell-based adoptive cell therapy, have recently been recognized as cancer treatments that show strong and durable responses even for advanced cancer patients with multiple metastas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43ac882dd444b3b10cf9642b049b31e2
https://doi.org/10.1007/978-4-431-55327-4_20
https://doi.org/10.1007/978-4-431-55327-4_20
Autor:
Akane Masuyama, Tsuyoshi Nakanishi, F. Ida, Masuo Kondoh, Naoya Koizumi, Taeko Hayakawa, Keiichi Tanaka, Emi Nakashima, Yoshiteru Watanabe, Makiko Fujii, Hiroyuki Mizuguchi
Publikováno v:
Placenta. 26:729-734
The transfer of genes of interest is a useful method for studying placental biology. Recombinant adenovirus (Ad) vector is an efficient vector for transgene expression. An interaction between the fiber of Ad and the coxsackievirus and adenovirus rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75da79229bb44ae169729543f0778c5
https://doi.org/10.1016/j.placenta.2004.10.010
https://doi.org/10.1016/j.placenta.2004.10.010