Cell migration directionality and speed are independently regulated by RasG and Gβ in Dictyostelium cells in electrotaxis

Autor: Taeck J. Jeon, Runchi Gao, Hyeseon Kim, Ara Lee, Pyeonghwa Jeon, Peter N. Devreotes, Min Zhao

Publikováno v: Biology Open, Vol 8, Iss 7 (2019)

Motile cells manifest increased migration speed and directionality in gradients of stimuli, including chemoattractants, electrical potential and substratum stiffness. Here, we demonstrate that Dictyostelium cells move directionally in response to an

Externí odkaz: https://doaj.org/article/4ac0c5ca2ba54fa593b4f15eef1be74e

WasC, a WASP family protein, is involved in cell adhesion and migration through regulation of F-actin polymerization in Dictyostelium

Autor: Pyeonghwa Jeon, Taeck J. Jeon

Publikováno v: Journal of Microbiology. 58:696-702

The actin cytoskeleton is involved in the regulation of cell morphology and migration. Wiskott-Aldrich Syndrome proteins (WASPs) play an important role in controlling actin polymerization by activating the Arp2/3 complex. The present study investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4249e5e49a0d12adca23a1b69305492c
https://doi.org/10.1007/s12275-020-0138-9

Membrane Targeting of C2GAP1 Enables Dictyostelium discoideum to Sense Chemoattractant Gradient at a Higher Concentration Range

Autor: Arjan Kortholt, Taeck J. Jeon, Smit Bhimani, Xi Wen, Henderikus Pots, Tian Jin, Xuehua Xu

Publikováno v: Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, 9:725073. Frontiers Media S.A.
Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Chemotaxis, which is G protein-coupled receptor (GPCR)-mediated directional cell migration, plays pivotal roles in diverse human diseases, including recruitment of leukocytes to inflammation sites and metastasis of cancer. It is still not fully under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a5c9e78a7bd94861f1914a244e6aa9
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/98554

Cell migration directionality and speed are independently regulated by RasG and Gβ in Dictyostelium cells in electrotaxis

Autor: Hyeseon Kim, Min Zhao, Ara Lee, Taeck J. Jeon, Runchi Gao, Pyeonghwa Jeon, Peter N. Devreotes

Publikováno v: Biology open, vol 8, iss 7
Biology Open, Vol 8, Iss 7 (2019)

Motile cells manifest increased migration speed and directionality in gradients of stimuli, including chemoattractants, electrical potential, and substratum stiffness. Here, we demonstrate that Dictyostelium cells move directionally in response to an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ae1d338c458f8ab627e49fdeb436f6
https://escholarship.org/uc/item/1559n7n4

Fucoidan Induces Cell Aggregation and Apoptosis in Osteosarcoma MG-63 Cells

Autor: Taeck J. Jeon, Hyeseon Kim

Publikováno v: Animal Cells and Systems. 20:186-192

Fucoidan, a sulfated polysaccharide found in brown algae, possesses various biological activities including anti-inflammatory and anti-cancer effects. In this study, we investigated the effects of fucoidan on the cell growth and morphology of human o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0f060cbbc19541d70b00e9b55f056d5
https://doi.org/10.1080/19768354.2016.1215349