Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Tae-sung Koo"'
Autor:
Da Hun Kim, Sa-Won Lee, Jun Hak Lee, Jin Woo Park, Sung Mo Park, Han-Joo Maeng, Tae-Sung Koo, Kwan Hyung Cho
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1242 (2024)
Background/Objectives: The aim of this work was to prepare and characterize gastroretentive floating combination tablets (GRCTs) containing 500 mg of amoxicillin trihydrate (AMX) and 125 mg of levofloxacin (LVX) that provide sustained drug release an
Externí odkaz:
https://doaj.org/article/aef9f76ad9dd4db0bf6550d646980947
Publikováno v:
Molecules, Vol 29, Iss 17, p 4048 (2024)
Vepdegestrant (formerly ARV-471), a novel proteolysis-targeting chimera (PROTAC), targets estrogen receptor alpha (ERα) for degradation, offering a promising option to treat advanced ER-positive breast cancer. We developed and validated a sensitive
Externí odkaz:
https://doaj.org/article/65517a88065942799c7a1d5a5b8dfc68
Publikováno v:
Journal of Analytical Science and Technology, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Poly (ADP-ribose) polymerase (PARP) inhibitors that are effective against ovarian and breast cancers with breast cancer susceptibility gene (BRCA) mutations have undesirable side effects, such as hematological toxicity. AZD5305, a selective
Externí odkaz:
https://doaj.org/article/e2e9e3d385bf4f43b57248604d35b16e
Autor:
Hae-In Choi, Taeheon Kim, Jin Woo Kim, Gi Ju Lee, Jinyoung Choi, Yoon-Jee Chae, Eunhee Kim, Tae-Sung Koo
Publikováno v:
Molecules, Vol 29, Iss 5, p 1004 (2024)
FAF1 (FAS-associated factor 1) is involved in the activation of Fas cell surface death receptors and plays a role in apoptosis and necrosis. In patients with Parkinson’s disease, FAF1 is overexpressed in dopaminergic neurons in the substantia nigra
Externí odkaz:
https://doaj.org/article/2ba95577337543b6b742d13143b7d0d6
Autor:
Seop Lee, Min-Soo Kim, Jong-Woo Jeong, Jung-woo Chae, Tae-Sung Koo, Han-Joo Maeng, Suk-Jae Chung, Kyeong-Ryoon Lee, Yoon-Jee Chae
Publikováno v:
Journal of Analytical Science and Technology, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Alpelisib is the first alpha-specific phosphatidylinositol-3-kinase (PI3K) inhibitor indicated for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative, PI3K catalytic subunit alpha-mutated, advanced,
Externí odkaz:
https://doaj.org/article/774a27d49e8047f9a7318a5c2a75099b
Autor:
Suk-Kyu Koh, Jong-Woo Jeong, Seo-In Choi, Rae Man Kim, Tae-Sung Koo, Kwan Hyung Cho, Kyoung-Won Seo
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-11 (2021)
Abstract Background Furosemide, a diuretic that acts on the loop of Henle, is commonly used to treat congestive heart failure in veterinary medicine. Some owners have difficulty in administering oral tablet medication to animal patients, which leads
Externí odkaz:
https://doaj.org/article/4fc5366957894b449047b94430e89330
Autor:
Joo Young An, Hee Seon Yang, Na Rae Park, Tae-sung Koo, Bungchul Shin, Eun Hee Lee, Sun Hang Cho
Publikováno v:
Nanoscale Research Letters, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Oleanolic acid has been used only as a subsidiary agent in cosmetic products. The aim of the study is to show the effect of oleanolic acid as an active ingredient for the alleviation of wrinkles in humans and to develop a polymeric micelle f
Externí odkaz:
https://doaj.org/article/41131dda497a4a1b9c7673049506ddbf
Autor:
Yoon-Jee Chae, Yoo-Kyung Song, Song-Hee Chae, Min Ju Kim, Jong Soon Kang, Jae-Young Lee, Tae-Sung Koo, Kyeong-Ryoon Lee
Publikováno v:
Journal of Analytical Science and Technology, Vol 11, Iss 1, Pp 1-9 (2020)
Abstract Larotrectinib is an orally administered drug and the first and only selective pan-tropomyosin receptor kinase (TRK) inhibitor in clinical development to treat cancer patients harboring a neurotrophic receptor tyrosine kinase gene fusion. In
Externí odkaz:
https://doaj.org/article/ad75e052ae434470a46e66a29ca60889
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 950 (2023)
The present study aimed to develop clear aqueous rebamipide (REB) eye drops to enhance solubility, stability, patient compliance, and bioavailability. For the preparation of a super-saturated 1.5% REB solution, the pH-modification method using NaOH a
Externí odkaz:
https://doaj.org/article/19ccce13c09a403cada5c6402bfb58e1
Publikováno v:
Journal of Advanced Veterinary and Animal Research, Vol 6, Iss 4, Pp 481-485 (2019)
Objective: We performed a randomized two-way crossover study to evaluate the pharmacokinetic profiles of two high-dose ascorbic acid (AA) after IV infusion in healthy beagle dogs. Materials and Methods: The dogs were administered IV AA at two doses o
Externí odkaz:
https://doaj.org/article/de55d51153be4aedb9ecfb842216ff79