Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Tae-Young Roh"'
Autor:
Seungchul Lee, Jaemyung Choi, Jihwan Park, Chang Pyo Hong, Daeseok Choi, Soeun Han, Kyuha Choi, Tae-Young Roh, Daehee Hwang, Ildoo Hwang
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-30 (2023)
Abstract Background Plants memorize previous pathogen attacks and are “primed” to produce a faster and stronger defense response, which is critical for defense against pathogens. In plants, cytosines in transposons and gene bodies are reported to
Externí odkaz:
https://doaj.org/article/2ffcc6124a1f4b11aa80d6fc2889dcf3
Autor:
Minji Lee, Hyun-Ja Ko, Sung-Wook Hong, Jungeun Park, Seokjin Ham, Mingyu Kim, Dong-il Kwon, Myeong-seok Lee, Tae-Young Roh, Kwang Soon Kim, You Jeong Lee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Dietary antigens affect the adaptive immunity of the host by inducing regulatory T cells and IgE-producing B cells. However, their roles in innate immune compartments such as innate lymphoid cells (ILCs) and intestinal epithelial cells (IECs
Externí odkaz:
https://doaj.org/article/219fd74fca6143b1a3c71b696bb83f90
Publikováno v:
Organoid, Vol 2 (2022)
Cell culture systems have been widely used to address fundamental questions in biology without sacrificing animals. Three-dimensional (3D) organoids provide more information on in vivo conditions than traditional culture systems because multiple cell
Externí odkaz:
https://doaj.org/article/38c04267981342f2ad0c5a92f998c7dd
Opportunistic detection of Fusobacterium nucleatum as a marker for the early gut microbial dysbiosis
Autor:
Ji-Won Huh, Tae-Young Roh
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background The essential roles of gut microbiome have been emphasized in modulating human health and disease. Fusobacterium nucleatum (F. nucleatum), an obligate Gram-negative microorganism residing in oral cavity, gastrointestinal tract and
Externí odkaz:
https://doaj.org/article/fd27304451aa48bb8cc145a17e93a849
Autor:
Hyae Yon Kweon, Mi-Ni Lee, Max Dorfel, Seungwoon Seo, Leah Gottlieb, Thomas PaPazyan, Nina McTiernan, Rasmus Ree, David Bolton, Andrew Garcia, Michael Flory, Jonathan Crain, Alison Sebold, Scott Lyons, Ahmed Ismail, Elaine Marchi, Seong-keun Sonn, Se-Jin Jeong, Sejin Jeon, Shinyeong Ju, Simon J Conway, Taesoo Kim, Hyun-Seok Kim, Cheolju Lee, Tae-Young Roh, Thomas Arnesen, Ronen Marmorstein, Goo Taeg Oh, Gholson J Lyon
Publikováno v:
eLife, Vol 10 (2021)
Amino-terminal acetylation is catalyzed by a set of N-terminal acetyltransferases (NATs). The NatA complex (including X-linked Naa10 and Naa15) is the major acetyltransferase, with 40–50% of all mammalian proteins being potential substrates. Howeve
Externí odkaz:
https://doaj.org/article/d85446a69857408ca85b40a4aca5a127
Autor:
So Dam Ha, Seokjin Ham, Min Young Kim, Ji Hyun Kim, Insoon Jang, Bo Bae Lee, Min Kyung Lee, Jin-Taek Hwang, Tae-Young Roh, TaeSoo Kim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
In yeast, Hda1 histone deacetylase complex (Hda1C) preferentially deacetylates H3 and H2B, but has also been implicated in global H4 deacetylation. Here, the authors provide evidence that Hda1C binds to hyperactive genes, where it specifically deacet
Externí odkaz:
https://doaj.org/article/5b53513e9eb54d71820ab18fd6d3ee68
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 2, Pp 1-13 (2019)
Rheumatoid arthritis: Understanding the regulation of disease-relevant genes Whole genome analysis of synoviocytes, specialized cells in the joint-lubricating synovial fluid, sheds light on the pathogenic mechanisms of rheumatoid arthritis (RA). Arou
Externí odkaz:
https://doaj.org/article/0dfafdbe6334434db8820757872c5c31
Autor:
Dae-Eun Jeong, Yujin Lee, Seokjin Ham, Dongyeop Lee, Sujeong Kwon, Hae-Eun H Park, Sun-Young Hwang, Joo-Yeon Yoo, Tae-Young Roh, Seung-Jae V Lee
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008617 (2020)
The oligosaccharyl transferase (OST) protein complex mediates the N-linked glycosylation of substrate proteins in the endoplasmic reticulum (ER), which regulates stability, activity, and localization of its substrates. Although many OST substrate pro
Externí odkaz:
https://doaj.org/article/1b879a5423da4b199bbc1d25db78b2fa
Autor:
Gunhwan Ko, Pan-Gyu Kim, Youngbum Cho, Seongmun Jeong, Jae-Yoon Kim, Kyoung Hyoun Kim, Ho-Yeon Lee, Jiyeon Han, Namhee Yu, Seokjin Ham, Insoon Jang, Byunghee Kang, Sunguk Shin, Lian Kim, Seung-Won Lee, Dougu Nam, Jihyun F. Kim, Namshin Kim, Seon-Young Kim, Sanghyuk Lee, Tae-Young Roh, Byungwook Lee
Publikováno v:
Genomics & Informatics, Vol 18, Iss 1 (2020)
The explosive growth of next-generation sequencing data has resulted in ultra-large-scale datasets and ensuing computational problems. In Korea, the amount of genomic data has been increasing rapidly in the recent years. Leveraging these big data req
Externí odkaz:
https://doaj.org/article/cedf9d54a4f84b7d80e78b149c2bcf1a
Autor:
Nhung Thi Hong Dinh, Jaewook Lee, Jaemin Lee, Sang Soo Kim, Gyeongyun Go, Seoyoon Bae, Ye In Jun, Yae Jin Yoon, Tae-Young Roh, Yong Song Gho
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Indoor pollutants are important problems to public health. Among indoor pollutants, indoor dust contains extracellular vesicles (EVs), which are associated with pulmonary inflammation. However, it has not been reported whether indoor dust EVs affect
Externí odkaz:
https://doaj.org/article/080c175fdb844e448d6cf7e87e90102f