Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tae-Yon Chun"'
Publikováno v:
Endocrinology. 144:1712-1717
In studies of animals, increases in aldosterone are associated with myocardial necrosis and fibrosis, and treatment with spironolactone, an antagonist of aldosterone, improved clinical outcomes in patients with heart failure. In the present study, we
Publikováno v:
Molecular Endocrinology. 14:1872-1881
Expression of the PRL gene is regulated by many factors, including cAMP, estradiol (E2), phorbol esters, epidermal growth factor (EGF), and TRH. The promoter region of the rat PRL gene has been shown to contain DNA sequences that are thought to suppo
Publikováno v:
Molecular and Cellular Endocrinology. 146:87-92
Chronic treatment of rats with the estrogens 17 β -estradiol or diethylstilbestrol (DES) induces pituitary tumors in Fischer 344 but not Brown–Norway or Sprague–Dawley rats. Functional loss of retinoblastoma susceptibility gene product (pRb), a
Publikováno v:
Proceedings of the National Academy of Sciences. 95:2325-2330
PR1 cells are a prolactin (PRL)-secreting cell line derived from a pituitary lactotroph tumor found in 17β-estradiol-treated Fischer 344 rats. We examined the effect of estrogen on cell proliferation and PRL synthesis under various culture condition
Autor:
Tae Yon Chun, Mary Anne Wagner, Syed Adeel Zaidi, J. Howard Pratt, Daniel G. Bichet, George J. Eckert, Chandan Saha, Lise Bankir
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 52(2)
Blacks have a greater tendency to retain Na than whites. The present study sought evidence for ethnic differences in parameters reflective of Na uptake by the Na,K,2Cl cotransporter in the thick ascending limb, namely, the urine concentration and uri
An increase in angiotensin II (ANG II) under conditions of high salt intake can result in renal damage. The extent to which ANG II does this directly or by way of stimulating aldosterone (Aldo) secretion is a subject of some debate. In the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140373529d2a374fb71121f19f6299df
https://europepmc.org/articles/PMC2519756/
https://europepmc.org/articles/PMC2519756/
Autor:
J. Howard Pratt, Tae-Yon Chun
Publikováno v:
Current opinion in endocrinology, diabetes, and obesity. 14(3)
Individuals with primary aldosteronism make up a substantial proportion of those with hypertension. Less well appreciated is what appears to be inappropriately elevated aldosterone secretion in hypertensive patients who do not meet the criteria for t
Autor:
Chandan Saha, Walter T. Ambrosius, J. Howard Pratt, Qianqian Zhao, George J. Eckert, Tae Yon Chun, Mary Anne Wagner
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 46(3)
Hypertension in blacks is more prevalent and less often controlled than the hypertension of other ethnic groups. We sought to explore the benefit of adding inhibitors of the epithelial sodium channel (ENaC), an aldosterone-regulated site of sodium re
Autor:
Tae-Yon Chun, J. Howard Pratt
Publikováno v:
Molecular and cellular endocrinology. 239(1-2)
Plasminogen activator inhibitor-1 (PAI-1) is an anti-thrombolytic factor that also promotes tissue fibrosis. Under certain conditions, exposure to aldosterone can result in cardiac fibrosis by an unknown mechanism. In the current study, we tested the
Autor:
Tae-Yon Chun, J. Howard Pratt
Publikováno v:
Trends in endocrinology and metabolism: TEM. 15(8)
Although the classical actions of aldosterone are mediated through genomic pathways, there is a growing recognition of important nongenomic responses to aldosterone. New data are presented from two laboratories showing a nongenomic effect of aldoster