Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Tae-Min Cho"'
Autor:
Minsu Park, Soeun Park, Juyeon Seo, Dongmi Ko, Seongjae Kim, Yong Koo Kang, Kee Dal Nam, So Ra Seuk, Tae-Min Cho, Eunsun Jung, Yoon-Jae Kim, Ji Young Kim, Jae Hong Seo
Publikováno v:
Cancer Research. 83:6121-6121
Purpose: Uncoupling protein 2 (UCP2) is a member of the mitochondrial anion carrier protein family that plays an important role in stabilizing the inner mitochondrial membrane potential (MMP, ΔΨm) and controlling reactive oxygen species (ROS) produ
Autor:
Ji Young Kim, Tae-Min Cho, Jung Min Park, Soeun Park, Minsu Park, Kee Dal Nam, Dongmi Ko, Juyeon Seo, Seongjae Kim, Eunsun Jung, Lee Farrand, Cong-Truong Nguyen, Van-Hai Hoang, Minh Thanh La, Jihyae Ann, Gibeom Nam, Hyun-Ju Park, Jeewoo Lee, Yoon-Jae Kim, Jae Hong Seo
Publikováno v:
Oncogene. 41(23)
Despite recent advances, there remains a significant unmet need for the development of new targeted therapies for triple-negative breast cancer (TNBC). Although the heat shock protein HSP90 is a promising target, previous inhibitors have had issues d
Autor:
Daeil Sung, Jae Hong Seo, Lee Farrand, Tae Min Cho, Cong Truong Nguyen, Yoon Jae Kim, Van-Hai Hoang, Jihyae Ann, Ji Young Kim, Eunhye Oh, Jeewoo Lee, Seojin Jang
Publikováno v:
Cancer Letters. 447:141-153
Triple-negative breast cancer (TNBC) is an aggressive heterogeneous disease with a divergent profile. It has an earlier tendency to form metastases and is associated with poor clinical outcomes due to the limited treatment options available. Heat-sho
Autor:
Kyung Chul Kim, Ji Hae Seo, Kyu-Won Kim, Mannkyu Hong, Hoon Choi, Jun Yong Kim, Jeewoo Lee, Jie Chen, Sang Kook Lee, Cong Truong Nguyen, Young-Ger Suh, Jihyae Ann, Seungbeom Lee, Woong Sub Byun, Jae Hong Seo, Ji Young Kim, Tae Min Cho, Ho Shin Kim, Hyun Ju Park, Van-Hai Hoang
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:1370-1381
On the basis of deguelin, a series of the B,C-ring truncated surrogates with N-substituted amide linkers were investigated as HSP90 inhibitors. The structure activity relationship of the template was studied by incorporating various substitutions on
Publikováno v:
Micromachines, Vol 15, Iss 10, p 1204 (2024)
In this study, we analyze metal–insulator–metal (MIM) capacitors with different thicknesses of SixNy film (650 Å, 500 Å, and 400 Å) and varying levels of film quality to improve their capacitance density. SixNy thicknesses of 650 Å, 500 Å, a
Externí odkaz:
https://doaj.org/article/a6ca8ba2a06f492bbabb2c7d76b98792
Publikováno v:
Micromachines, Vol 15, Iss 10, p 1231 (2024)
The development of metal–insulator–semiconductor (MIS) capacitors requires device miniaturization and excellent electrical properties. Traditional SiO2 gate dielectrics have reached their physical limits. In this context, high-k materials such as
Externí odkaz:
https://doaj.org/article/a49b4dcac439452aab31dd6530b837c9
Publikováno v:
Micromachines, Vol 15, Iss 9, p 1171 (2024)
Nanogenerators have garnered significant interest as environmentally friendly and potential energy-harvesting systems. Nanogenerators can be broadly classified into piezo-, tribo-, and hybrid nanogenerators. The hybrid nanogenerator used in this expe
Externí odkaz:
https://doaj.org/article/65b2bee152784ca9b052737b963ea8f4
Autor:
Jae Hong Seo, Seojin Jang, Hyunsook An, Daeil Sung, Ji Young Kim, Yoon Jae Kim, Tae Min Cho, Lee Farrand, Eunhye Oh
Publikováno v:
International Journal of Cancer. 143:1978-1993
Tumor metastasis remains the cause of 90% of cancer-related deaths. Cancer stem cells (CSC) are thought to be responsible for the aggressive and metastatic nature of triple-negative breast cancers (TNBC), and new therapeutic strategies are being devi
Autor:
Daeil Sung, Yoon Jae Kim, Ji Young Kim, Hyunsook An, Nahyun Lee, Eunhye Oh, Tae Min Cho, Youngkwan Cho, Jae Hong Seo
Publikováno v:
Cellular Signalling. 36:230-239
Ubiquitin-specific protease 34 (USP34) is a deubiquitinating enzyme that regulates Axin stability and plays a critical role in Wnt/β-catenin signaling. We sought to investigate the role of USP34 on epithelial-mesenchymal (EMT) induction and its effe
Publikováno v:
Biochemical and Biophysical Research Communications. 486:1069-1076
In the presence of copper (Cu), disulfiram (DSF) suppresses properties associated with cancer stem cells (CSCs) in breast cancer, but the mechanism of action is poorly understood. In the present study, we observed that DSF/Cu treatment induced apopto