Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Tae-Min Cho"'
Autor:
Minsu Park, Soeun Park, Juyeon Seo, Dongmi Ko, Seongjae Kim, Yong Koo Kang, Kee Dal Nam, So Ra Seuk, Tae-Min Cho, Eunsun Jung, Yoon-Jae Kim, Ji Young Kim, Jae Hong Seo
Publikováno v:
Cancer Research. 83:6121-6121
Purpose: Uncoupling protein 2 (UCP2) is a member of the mitochondrial anion carrier protein family that plays an important role in stabilizing the inner mitochondrial membrane potential (MMP, ΔΨm) and controlling reactive oxygen species (ROS) produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c24d8a6c3189a8b195132e894bd05d27
https://doi.org/10.1158/1538-7445.am2023-6121
https://doi.org/10.1158/1538-7445.am2023-6121
Autor:
Ji Young Kim, Tae-Min Cho, Jung Min Park, Soeun Park, Minsu Park, Kee Dal Nam, Dongmi Ko, Juyeon Seo, Seongjae Kim, Eunsun Jung, Lee Farrand, Cong-Truong Nguyen, Van-Hai Hoang, Minh Thanh La, Jihyae Ann, Gibeom Nam, Hyun-Ju Park, Jeewoo Lee, Yoon-Jae Kim, Jae Hong Seo
Publikováno v:
Oncogene. 41(23)
Despite recent advances, there remains a significant unmet need for the development of new targeted therapies for triple-negative breast cancer (TNBC). Although the heat shock protein HSP90 is a promising target, previous inhibitors have had issues d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8c83adb3b52659f9fdd63388f985e8
https://pubmed.ncbi.nlm.nih.gov/35501463
https://pubmed.ncbi.nlm.nih.gov/35501463
Autor:
Daeil Sung, Jae Hong Seo, Lee Farrand, Tae Min Cho, Cong Truong Nguyen, Yoon Jae Kim, Van-Hai Hoang, Jihyae Ann, Ji Young Kim, Eunhye Oh, Jeewoo Lee, Seojin Jang
Publikováno v:
Cancer Letters. 447:141-153
Triple-negative breast cancer (TNBC) is an aggressive heterogeneous disease with a divergent profile. It has an earlier tendency to form metastases and is associated with poor clinical outcomes due to the limited treatment options available. Heat-sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1452bbb24bf41e2e2633c60ddcfad5
https://doi.org/10.1016/j.canlet.2019.01.029
https://doi.org/10.1016/j.canlet.2019.01.029
Autor:
Kyung Chul Kim, Ji Hae Seo, Kyu-Won Kim, Mannkyu Hong, Hoon Choi, Jun Yong Kim, Jeewoo Lee, Jie Chen, Sang Kook Lee, Cong Truong Nguyen, Young-Ger Suh, Jihyae Ann, Seungbeom Lee, Woong Sub Byun, Jae Hong Seo, Ji Young Kim, Tae Min Cho, Ho Shin Kim, Hyun Ju Park, Van-Hai Hoang
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:1370-1381
On the basis of deguelin, a series of the B,C-ring truncated surrogates with N-substituted amide linkers were investigated as HSP90 inhibitors. The structure activity relationship of the template was studied by incorporating various substitutions on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5095b67a18b84faa2d21e358e44e3c
https://doi.org/10.1016/j.bmc.2019.02.040
https://doi.org/10.1016/j.bmc.2019.02.040
Autor:
Jae Hong Seo, Seojin Jang, Hyunsook An, Daeil Sung, Ji Young Kim, Yoon Jae Kim, Tae Min Cho, Lee Farrand, Eunhye Oh
Publikováno v:
International Journal of Cancer. 143:1978-1993
Tumor metastasis remains the cause of 90% of cancer-related deaths. Cancer stem cells (CSC) are thought to be responsible for the aggressive and metastatic nature of triple-negative breast cancers (TNBC), and new therapeutic strategies are being devi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb044b9b65445a02d7be0816f70ebb01
https://doi.org/10.1002/ijc.31585
https://doi.org/10.1002/ijc.31585
Autor:
Daeil Sung, Yoon Jae Kim, Ji Young Kim, Hyunsook An, Nahyun Lee, Eunhye Oh, Tae Min Cho, Youngkwan Cho, Jae Hong Seo
Publikováno v:
Cellular Signalling. 36:230-239
Ubiquitin-specific protease 34 (USP34) is a deubiquitinating enzyme that regulates Axin stability and plays a critical role in Wnt/β-catenin signaling. We sought to investigate the role of USP34 on epithelial-mesenchymal (EMT) induction and its effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcd262915bb038c3e9c009ccfd78400
https://doi.org/10.1016/j.cellsig.2017.05.009
https://doi.org/10.1016/j.cellsig.2017.05.009
Publikováno v:
Biochemical and Biophysical Research Communications. 486:1069-1076
In the presence of copper (Cu), disulfiram (DSF) suppresses properties associated with cancer stem cells (CSCs) in breast cancer, but the mechanism of action is poorly understood. In the present study, we observed that DSF/Cu treatment induced apopto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1515f6482cbc6e8c89d8691bd189e114
https://doi.org/10.1016/j.bbrc.2017.03.164
https://doi.org/10.1016/j.bbrc.2017.03.164
Autor:
Tae Min Cho1, Yeon Seok Choo1 chooyeonseok@kaist.ac.kr, Min Jung Lee1, Hyeon Cheol Oh1, Byung Chai Lee1, Tae Hak Park2, Young Sug Shin2
Publikováno v:
Journal of Adhesion Science & Technology. 2009, Vol. 23 Issue 15, p1875-1882. 8p. 1 Black and White Photograph, 3 Diagrams, 3 Charts, 2 Graphs.
Autor:
Ji Young Kim, Hyunsook An, Nahyun Lee, Eunhye Oh, Jae Hong Seo, Youngkwan Cho, Tae Min Cho, Daeil Sung
Publikováno v:
Cancer Letters. 379:39-48
HER2-positive breast tumors are known to harbor cancer stem-like cell populations and are associated with an aggressive tumor phenotype and poor clinical outcomes. Disulfiram (DSF), an anti-alcoholism drug, is known to elicit cytotoxicity in many can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39bfa7974bab12dcb992290e1b04d40
https://doi.org/10.1016/j.canlet.2016.05.026
https://doi.org/10.1016/j.canlet.2016.05.026
Autor:
Eunhye Oh, Yoon-Jae Kim, Seojin Jang, Tae-Min Cho, Soeun Park, Jung Min Park, Minsu Park, Ji Young Kim, Jae Hong Seo
Publikováno v:
Cancer Research. 79:3457-3457
Triple-negative breast cancers (TNBC) with higher cancer stem-like populations are reported to exhibit a more aggressive metastatic phenotype. In the present study, we investigated the effects of flubendazole, a candidate drug for repurposing and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c9eaf1dc327ef70c29adfe02758ef42
https://doi.org/10.1158/1538-7445.am2019-3457
https://doi.org/10.1158/1538-7445.am2019-3457