Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Tae-Hwe Heo"'
Autor:
Aeri Park, Tae-Hwe Heo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116256- (2024)
Anti-IL-17A antibodies, such as secukinumab and ixekizumab, are effective proinflammatory cytokine inhibitors for autoimmune disorders, including psoriasis. However, anti-IL-17A small molecule treatments are yet to be commercialized. Celastrol, a nat
Externí odkaz:
https://doaj.org/article/694ff1d5ea2347f094a580e5bf588203
Autor:
Hye Jin Kim, Lee Kyung Kim, Anna Kim, Khin Myo Htwe, Tae-Hwe Heo, Kye Jung Shin, Hee Jung Kim, Kee Dong Yoon
Publikováno v:
Molecules, Vol 29, Iss 13, p 2981 (2024)
Piper attenuatum Buch-Ham, a perennial woody vine belonging to the Piperaceae family, is traditionally used in Southeast Asia for treating various ailments such as malaria, headache, and hepatitis. This study described the isolation and identificatio
Externí odkaz:
https://doaj.org/article/28085e8147444a768e8e4e375ab35e22
Autor:
Young-Jin Jeong, Sun-Ae Park, Yeon-Hwa Park, Lee Kyung Kim, Hae-Ri Lee, Hee Jung Kim, Tae-Hwe Heo
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0302119 (2024)
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation and swelling. Several studies have demonstrated that RA fibroblast-like synovial cells (RA-FLS) play an important role in RA pathogenesis. Activated RA-FLS contrib
Externí odkaz:
https://doaj.org/article/ad244ff97ea2491db732d470480d1ca4
Autor:
Hae-Ri Lee, Young-Jin Jeong, Joong-Woon Lee, JooYeon Jhun, Hyun Sik Na, Keun-Hyung Cho, Seok Jung Kim, Mi-La Cho, Tae-Hwe Heo
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0281834 (2023)
Interleukin-1β (IL-1β) is one of the most potent pro-inflammatory cytokines implicated in a wide range of autoinflammatory, autoimmune, infectious, and degenerative diseases. Therefore, many researchers have focused on developing therapeutic molecu
Externí odkaz:
https://doaj.org/article/d3b97faa2dd74ba68a9b65d3c373f116
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1018 (2023)
Long non-coding RNAs (lncRNAs) are implicated in the initiation and progression of a variety of tumors, including endometrial cancer. However, the mechanisms of lncRNA in endometrial cancer formation and progression remain largely unknown. In this st
Externí odkaz:
https://doaj.org/article/884167f66ad742d798d96c6ddef256e0
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6038 (2023)
Butea monosperma (Fabaceae) has been used in traditional Indian medicine to treat a variety of ailments, including abdominal tumors. We aimed to investigate the anti-IL-6 activity of butein in ovarian cancer and elucidate the underlying molecular mec
Externí odkaz:
https://doaj.org/article/30e29e41d0c04351970fba6b4c674b55
Publikováno v:
Asian-Australasian Journal of Animal Sciences, Vol 33, Iss 4, Pp 670-677 (2020)
Objective Interleukin-6 (IL-6) is a T cell-derived B cell stimulating factor which plays an important role in inflammatory diseases. In this study, the pharmacokinetic properties of LMT-28 including physicochemical property, in vitro liver microsomal
Externí odkaz:
https://doaj.org/article/2a9bc06634cd46ff884a11ce197cf234
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8693 (2021)
Persistent HPV (Human Papillomavirus) infection is the primary cause of cervical cancer. Despite the development of the HPV vaccine to prevent infections, cervical cancer is still a fatal malignant tumor and metastatic disease, and it is often diffic
Externí odkaz:
https://doaj.org/article/5eab9a90b1364de1b7f534432e4ed764
Publikováno v:
Biological Research, Vol 47, Iss 0, Pp 1-9 (2014)
BACKGROUND: Tuberculosis (TB) is a respiratory tract disease caused by Mycobacterium tuberculosis infection. M. tuberculosis exploits immune privilege to grow and divide in pleural macrophages. Fibrates are associated with the immune response and con
Externí odkaz:
https://doaj.org/article/71b5c931ea3c49e9a910eed98e7bda57
Autor:
Sungjin Lee, Karabasappa Mailar, Mi Il Kim, Minkyung Park, Jiseon Kim, Dal-Hee Min, Tae-Hwe Heo, Soo Kyung Bae, Wonjun Choi, Choongho Lee
Publikováno v:
Viruses, Vol 11, Iss 10, p 890 (2019)
Oligostilbenoid compounds, a group of resveratrol multimers, display several anti-microbial activities through the neutralization of cytotoxic oxidants, and by inhibiting essential host and viral enzymes. In our previous study, we identified a series
Externí odkaz:
https://doaj.org/article/fa91da6a3a7b47c1bb0420f5512adf2e