Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tae Y. Yune"'
Publikováno v:
Neurobiology of Disease, Vol 95, Iss , Pp 66-81 (2016)
The disruption of the blood–spinal cord barrier (BSCB) by matrix metalloprotease (MMP) activation is a detrimental event that leads to blood cell infiltration, inflammation, and apoptosis, thereby contributing to permanent neurological disability a
Externí odkaz:
https://doaj.org/article/827c9d11baa14ff98d4458e5ce50f186
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 141-151 (2015)
The activation of microglia after spinal cord injury (SCI) contributes to secondary damage by producing pro-inflammatory cytokines and mediators, leading to cell death of oligodendrocytes and neurons. Here, we show that matrix metalloprotease-3 (MMP-
Externí odkaz:
https://doaj.org/article/5047f4696a8c43269a1f45a97f4fb5dd
Publikováno v:
Neurobiology of Disease, Vol 39, Iss 3, Pp 272-282 (2010)
Here, we first demonstrated the neuroprotective effect of acupuncture after SCI. Acupuncture applied at two specific acupoints, Shuigou (GV26) and Yanglingquan (GB34) significantly alleviated apoptotic cell death of neurons and oligodendrocytes, ther
Externí odkaz:
https://doaj.org/article/015865eafda64b3192d53ebe3a82ae8a
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73948 (2013)
Acupuncture (AP) has been used worldwide to relieve pain. However, the mechanism of action of AP is poorly understood. Here, we found that AP relieved neuropathic pain (NP) by inhibiting Jun-N-terminal kinase (JNK) activation in astrocytes after spin
Externí odkaz:
https://doaj.org/article/ffa705ad130c4d87bf93af5b6e358937
Autor:
Chhavy Tep, Sung Ok Yoon, Kun Ping Lu, Takafumi Uchida, Xiao Zhen Zhou, Tae Y. Yune, Qi Ming Li
Publikováno v:
The Journal of Neuroscience. 27:8395-8404
Although oligodendrocytes undergo apoptosis after spinal cord injury, molecular mechanisms responsible for their death have been unknown. We report that oligodendrocyte apoptosis is regulated oppositely by c-Jun N-terminal kinase 3 (JNK3) and protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b6003aa0e2817118d60f7b369e7d92
https://doi.org/10.1523/jneurosci.2478-07.2007
https://doi.org/10.1523/jneurosci.2478-07.2007
Autor:
Tae Y. Yune, Sang M. Lee, Sun J. Kim, Hong K. Park, Young J. Oh, Young C. Kim, George J. Markelonis, H. Oh
Publikováno v:
Journal of Neurotrauma. 21:1778-1794
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e203a4790455a83b9ed931c17b1a4c
https://doi.org/10.1089/0897715042664858
https://doi.org/10.1089/0897715042664858
Autor:
Tae H. Oh, Young Kook Lee, Young Chul Kim, Tae Y. Yune, Young J. Oh, S. J. Kim, Sang M. Lee, Do W. Park, George J. Markelonis
Publikováno v:
Journal of Neurotrauma. 20:1017-1027
We examined the effects of minocycline, an anti-inflammatory drug, on functional recovery following spinal cord injury (SCI). Rats received a mild, weight-drop contusion injury to the spinal cord and were treated with the vehicle or minocycline at a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b162fe6d2645b2388f787d48b4ba5e97
https://doi.org/10.1089/089771503770195867
https://doi.org/10.1089/089771503770195867
Publikováno v:
Journal of neurochemistry. 121(5)
The disruption of blood-spinal cord barrier (BSCB) after spinal cord injury (SCI) elicits an intensive local inflammation by the infiltration of blood cells such as neutrophils and macrophages, leading to cell death and permanent neurological disabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8996bb795b30061bc5c9391720987e37
https://pubmed.ncbi.nlm.nih.gov/22409448
https://pubmed.ncbi.nlm.nih.gov/22409448
Publikováno v:
Journal of neurochemistry. 110(4)
Inflammation has been known to play an important role in the pathogenesis after spinal cord injury (SCI). Microglia are activated after injury and produce a variety of proinflammatory factors such as tumor necrosis factor-alpha, interleukin-1beta, cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::002eff2fa5d8f3be71379703987cd93f
https://pubmed.ncbi.nlm.nih.gov/19519665
https://pubmed.ncbi.nlm.nih.gov/19519665
Autor:
Tae Y. Yune, Tae H. Oh, Song W. Shin, Mi J. Chang, Young Choong Kim, Young J. Oh, Sun J Kim, Ching T. Han, Young Bok Lee, Hyewhon Rhim, George J. Markelonis, Moon L. Shin
Publikováno v:
Journal of neurotrauma. 20(2)
We showed previously that, after spinal cord injury (SCI), tumor necrosis factor-alpha (TNF-alpha) may serve as an external signal, initiating apoptosis in neurons and oligodendrocytes. To further characterize the apoptotic cascade initiated by TNF-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb156d6458f05ba92a8a88bad4f18ba
https://pubmed.ncbi.nlm.nih.gov/12675973
https://pubmed.ncbi.nlm.nih.gov/12675973