Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Tae Kanai"'
Autor:
Taisuke Itaya, Tae Kanai
Publikováno v:
Chemical and Pharmaceutical Bulletin. 50:1584-1588
1-Benzylwye (8) underwent electrophilic substitution at the 7-position in the presence of phosgene and pyridine in tetrahydrofuran (THF) to afford the 1,4-dihydropyridines (11, 10, and 14) together with the carboxylic acid 6 and its methyl ester 2 af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1317925b48559530c73c633ec9971793
https://doi.org/10.1248/cpb.50.1584
https://doi.org/10.1248/cpb.50.1584
Publikováno v:
Chemical and Pharmaceutical Bulletin. 50:530-533
An improved synthesis of 3-beta-D-ribofuranosylwybutine (2) has been achieved by the Wittig reaction between 4,6-dimethyl-9-oxo-3-[2,3,5-tris-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-4,9-dihydro-3H-imidazo[1,2-a]-purine-7-carbaldehyde (8) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0832cde8460cc4e59d955ceab5d39c8
https://doi.org/10.1248/cpb.50.530
https://doi.org/10.1248/cpb.50.530
Autor:
Tae Kanai, Taisuke Itaya
Publikováno v:
Chemical and Pharmaceutical Bulletin. 50:1318-1326
The first synthesis of (alphaS,betaS)-beta-hydroxy-alpha-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-3-beta-D-ribofuranosyl-4,9-dihydro-3H-imidazo[1,2-a]purine-7-butanoic acid methyl ester [(alphaS,betaS)-11] has been achieved by OsO(4) oxidation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab92ae4c1362b86a2b5b3a3a6e0bd943
https://doi.org/10.1248/cpb.50.1318
https://doi.org/10.1248/cpb.50.1318
Autor:
Taisuke Itaya, Tae Kanai
Publikováno v:
Tetrahedron Letters. 40:8003-8006
The unstable minor nucleosides, wyosine, wybutosine, and β-hydroxywybutosine, were isolated from tRNAs in sufficient amounts for determination of their structures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14879110ecfb90a49158a0526de494c1
https://doi.org/10.1016/s0040-4039(99)01624-x
https://doi.org/10.1016/s0040-4039(99)01624-x
Publikováno v:
Tetrahedron. 55:6075-6080
Catalytic hydrogenolysis of (S)-2-phenyl-1,2-propanediol (2), prepared by an asymmetric dihydroxylation of α-methylstyrene (1) with AD-mix-α, over Pearlman's catalyst gave (S)-2-phenyl-1-propanol (3). This method was applied to the synthesis of opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da4918ae2d9a59635882f2fa68daea99
https://doi.org/10.1016/s0040-4020(99)00279-3
https://doi.org/10.1016/s0040-4020(99)00279-3
Publikováno v:
Chemical and Pharmaceutical Bulletin. 47:1297-1300
Alkylation of 8-oxoadenosine (13) with 4-benzyloxy-3, 5-dibromobenzyl bromide (20), followed by Dimroth rearrangement and acid hydrolysis, provided N-(3, 5-dibromo-4-hydroxybenzyl)-8-oxoadenosine (15). The 2'-deoxy version of this reaction sequence a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb5768a6e67a95639c4847db6796e1d0
https://doi.org/10.1248/cpb.47.1297
https://doi.org/10.1248/cpb.47.1297
Autor:
Shin-ichi Ohyama, Taisuke Itaya, Yoshihisa Shirasaki, Yukiko Ono, Tae Kanai, Nobuhiro Muramoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 47:1464-1472
1-Benzyl-4, 6-dimethyl-4, 9-dihydro-1H-imidazo[1, 2-α]purin-9-one bearing an alkyl, a 1-alkenyl, a hydroxymethyl, a methoxymethyl, or a formyl group at the 7-position (3a-e) underwent rearrangement through fission and recyclization of the pyrimidine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba9ec25d3ea488f9ccca823e02356e3f
https://doi.org/10.1248/cpb.47.1464
https://doi.org/10.1248/cpb.47.1464
Publikováno v:
Tetrahedron Letters. 38:1979-1982
The synthesis of the title compounds started with the Vilsmeier reaction of 3-[2,3,5- tris -O-(tert- butyldimethylsilyl)-β- d - ribofuranosyl]wye ( 5b ) and proceeded through the Wittig reaction with ( R )- N -(methoxycarbonyl)-3-(triphenylphosphoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96c1e6f2fad4ab259206caa3164b1c25
https://doi.org/10.1016/s0040-4039(97)00253-0
https://doi.org/10.1016/s0040-4039(97)00253-0
Publikováno v:
Chemical and Pharmaceutical Bulletin. 45:1582-1588
3-Alkyl-8-hydroxyadenines (5) have been shown to undergo regioselective methylation at the 7- or 9-position depending on the reaction conditions. Thus, treatment of 5a, c with dimetyl sulfate in aqueous NaOH provided 3-alkyl-7-methyl-8-oxoadenines (6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1951a577b513edef9535502064897984
https://doi.org/10.1248/cpb.45.1582
https://doi.org/10.1248/cpb.45.1582
Publikováno v:
Chemical and Pharmaceutical Bulletin. 45:75-80
1-Methyl-5-(methylamino)imidazole-4-carbonitrile (4a) afforded three minor ring-opened products (5a, 6a, 10a) besides its 2-oxo derivative 3a on treatment with ethyl chloroformate in aqueous sodium bicarbonate. The geometrical isomers of these trisub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fb459ebcc2d3d2d6e5b172911990323
https://doi.org/10.1248/cpb.45.75
https://doi.org/10.1248/cpb.45.75