Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Tae Heung Kang"'
Autor:
Hee Dong Han, Tae Heung Kang, Yeong-Min Park, Jeong-Won Lee, Ji Eun Won, Youngseon Byeon, Tae In Wi, Chan Mi Lee, Ju Hyeong Lee, YoungJoo Lee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/619665c15d6e48c8bf0f3602d787ca36
Autor:
Tae Heung Kang, Jung Hwa Park, Andrew Yang, Hyun Jin Park, Sung Eun Lee, Young Seob Kim, Gun-Young Jang, Emily Farmer, Brandon Lam, Yeong-Min Park, Chien-Fu Hung
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
AnnexinV has been shown to bind phosphatidylserine expressed by chemotherapy-induced apoptotic cells increasing their immunogeneicity. Here, the authors demonstrate in a preclinical tumor model that fusing tumor-antigen peptide to Annexin V enhances
Externí odkaz:
https://doaj.org/article/2fb1fbb0de664cbdac06f9837a479b3c
Autor:
So Eun Youn, Fen Jiang, Hye Yun Won, Da Eun Hong, Tae Heung Kang, Yun-Yong Park, Sang Seok Koh
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11414 (2022)
PAUF, a tumor-promoting protein secreted by cancer cells, exerts paracrine effects on immune cells through TLR4 receptors expressed on immune cell surfaces. This study aimed to investigate if PAUF elicits autocrine effects on pancreatic cancer (PC) c
Externí odkaz:
https://doaj.org/article/c43ce8421a9149d282ecc7ec7edb012f
Autor:
Tae Heung Kang, Chih-Ping Mao, Young Seob Kim, Tae Woo Kim, Andrew Yang, Brandon Lam, Ssu-Hsueh Tseng, Emily Farmer, Yeong-Min Park, Chien-Fu Hung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract The tumor microenvironment exists in a state of dynamic equilibrium, in which a balance of agonist and antagonist signals govern the anti-tumor immune responses. Previous studies have shown that chemotherapy could shift this balance in favor
Externí odkaz:
https://doaj.org/article/d7b47040938045bbad53169253d14929
Autor:
Chanyoung Song, Hathaichanok Phuengkham, Young Seob Kim, Van Vuong Dinh, Inho Lee, Il Woo Shin, Hong Sik Shin, Seung Mo Jin, Soong Ho Um, Hyunseung Lee, Kwan Soo Hong, Seon-Mi Jin, Eunji Lee, Tae Heung Kang, Yeong-Min Park, Yong Taik Lim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The limited efficacy of current immunotherapy suggests low antigen-specific T cells and immunosuppressive factors in tumor microenvironment (TME). Here, the authors develop a syringeable immunomodulatory multi-domain nanogel that can reprogram the TM
Externí odkaz:
https://doaj.org/article/74f56ede70494663b8680f81b8197124
Autor:
Sung Yong Lee, Jee Youn Oh, Tae Heung Kang, Hyun Seock Shin, Max A. Cheng, Emily Farmer, T.-C. Wu, Chien-Fu Hung
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-8 (2019)
Abstract Background Endoplasmic reticulum stress has a profound effect on cancer cell proliferation and survival, and also has the capacity to activate cells of the adaptive immune system. Multimodal treatment methods that utilize and combine convent
Externí odkaz:
https://doaj.org/article/9afff5b159544429802ca845115f0e17
Autor:
Hyun Jin Park, Gun-Young Jang, Young Seob Kim, Jung Hwa Park, Sung Eun Lee, Manh-Cuong Vo, Je-Jung Lee, Hee Dong Han, In Duk Jung, Tae Heung Kang, Yeong-Min Park
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Dendritic cells (DCs) are professional antigen presenting cells (APCs), which can activate antigen-specific CD8+ T cell immunity, resulting in tumor clearance. Immature DCs are usually stimulated by various adjuvants through their
Externí odkaz:
https://doaj.org/article/1cd143757e744b09a088290bbaa52a8e
Autor:
Ga Hee Kim, Ji Eun Won, Yeongseon Byeon, Min Gi Kim, Tae In Wi, Jae Myeong Lee, Yun-Yong Park, Jeong-Won Lee, Tae Heung Kang, In Duk Jung, Byung Cheol Shin, Hyung Jun Ahn, Young Joo Lee, Anil K. Sood, Hee Dong Han, Yeong-Min Park
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1394-1402 (2018)
Angiogenesis plays an essential role in the growth and metastasis of tumor cells, and the modulation of angiogenesis can be an effective approach for cancer therapy. We focused on silencing the angiogenic gene PLXDC1 as an important factor for anti-a
Externí odkaz:
https://doaj.org/article/dbdd2a32aa0a451a9444d27e81dca682
Autor:
Jung Hwa Park, Jong-Hwa Jang, Eun Jung Choi, Young Seob Kim, Eun Ji Lee, In Duk Jung, Hee Dong Han, T-C Wu, Chien-Fu Hung, Tae Heung Kang, Yeong-Min Park
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 424-436 (2016)
Abstract The identification of HMGB1 as a late mediator in sepsis has highlighted HMGB1 as a promising therapeutic target for sepsis treatment. Recent studies have revealed that annexin A5, a 35 kDa Ca2+-dependent phospholipid binding protein, exerts
Externí odkaz:
https://doaj.org/article/56cf02dc4d60458c974599993a52b308
Autor:
Young Seob Kim, Hyun Jin Park, Jung Hwa Park, Eun Ji Hong, Gun-Young Jang, In Duk Jung, Hee Dong Han, Seung-Hyun Lee, Manh-Cuong Vo, Je-Jung Lee, Andrew Yang, Emily Farmer, T.-C. Wu, Tae Heung Kang, Yeong-Min Park
Publikováno v:
OncoImmunology, Vol 7, Iss 10 (2018)
Dendritic cell (DC)-based vaccines are recognized as a promising immunotherapeutic strategy against cancer. Various adjuvants are often incorporated to enhance the modest immunogenicity of DC vaccines. More specifically, many of the commonly used adj
Externí odkaz:
https://doaj.org/article/2b11ad9d28cd48b0af0c2244af31e573