Výsledky vyhledávání - "Tadeusz Pacuszka"

The oxidation products of melatonin derivatives exhibit acetylcholinesterase and butyrylcholinesterase inhibitory activity

Autor: Zuzanna Molęda, Mirosława Panasiewicz, Krystyna Wojtasiewicz, Anna Zawadzka, Tadeusz Pacuszka, Zbigniew Czarnocki, Jan K. Maurin, Aleksandra Siwicka

Publikováno v: Journal of Pineal Research. 45:40-49

It is already well documented that melatonin exhibits strong antioxidant properties. It traps several reactive oxygen species including singlet oxygen, peroxyl and hydroxyl radicals. Also, peroxynitrite-induced reactions are inhibited by melatonin. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb60296333822517964b1bf23d2c216
https://doi.org/10.1111/j.1600-079x.2008.00554.x

Zobrazit plný text záznamu

Glucosylceramide synthase inhibitors D-PDMP and D-EtDO-P4 decrease the GM3 ganglioside level, differ in their effects on insulin receptor autophosphorylation but increase Akt1 kinase phosphorylation in human hepatoma HepG2 cells

Autor: Mirosława Panasiewicz, Hanna Domek, Natalia Fedoryszak-Kuśka, Tadeusz Pacuszka

Publikováno v: Acta biochimica Polonica. 63(2)

Gangliosides function as modulators of several cell growth related receptors. It was shown for caveolin-rich adipocytes, that GM3 ganglioside binds to insulin receptor (IR), dissociates its complex with caveolin, and thus lowers IR autophosphorylatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e439881c88d03fb9a1ed88dcf991b36
https://pubmed.ncbi.nlm.nih.gov/27172362

Zobrazit plný text záznamu

Preparation of photoreactive 12-[(4-azidosalicyl)amino] dodecanoic acid acylated derivatives of gangliosides radioioiodinated to high specific radioactivity

Autor: Tadeusz Pacuszka, Mirosława Panasiewicz

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 43:1255-1263

We describe the preparation of 125 I labeled 12[(4-azidosalicyl)amino]dodecanoic acid (ASD) acylated derivatives of G M3 , G D3 , G M1 and SPG gangliosides. Gangliosides isolated from natural sources were deacylated, reacylated with ASD and radioiodi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7032a42b5cd392304e367728e4f0425f
https://doi.org/10.1002/1099-1344(200011)43:13<1255::aid-jlcr414>3.0.co

Zobrazit plný text záznamu

Preparation of Alexa Fluor 350-conjugated nonradioactive or 3H-labeled GM1 ganglioside derivatives with different ceramides

Autor: Hanna Domek, Natalia Fedoryszak, Tadeusz Pacuszka, Mirosława Panasiewicz

Publikováno v: Analytical Biochemistry. 385:168-170

Alexa Fluor 350 hydrazide (AF) was coupled to the aldehyde group at C-6 of terminal galactose of oxidized GM1 gangliosides containing different fatty acid residues (GM1s). The AF–GM1 hydrazones obtained were reduced with NaBH4 or [3H]NaBH4 and puri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ed29127a806ff7b205504f0a6f966c
https://doi.org/10.1016/j.ab.2008.10.017

Zobrazit plný text záznamu

Photochemical labeling of HL-60 cell membrane proteins with radioiodinated, 4-azidosalicylic acid acylated derivatives of gangliosides

Autor: Grazyna Hoser, Mirosława Panasiewicz, Maciej Kawalec, Tadeusz Pacuszka

Publikováno v: Acta Biochimica Polonica. 45:403-415

To detect HL-60 human promyelocytic leukemia cell proteins involved in the uptake of gangliosides from the culture medium we used photoreactive, 4-azidosalicylic acid (ASA) acylated and radioiodinated (200 Ci/mmole) derivatives of GM3, GD3, GM1, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b9fa1ccafd618ff5bde28db5c087d5
https://doi.org/10.18388/abp.1998_4235

Zobrazit plný text záznamu

Anti-fucosyl-GM1 ganglioside IgG and IgM autoantibodies in human serum: no link to pathology

Autor: Aleksandra Lewartowska, Grażyna Adler, Izabela Targonska, Mirosława Panasiewicz, Maria Strugalska, Tadeusz Pacuszka

Publikováno v: Immunology Letters. 52:89-93

Anti-fucosyl-GM1 ganglioside antibodies were detected in sera of five persons: four patients with autoimmune neuropathies and, more recently, IgG antibodies in one with Graves' disease (Adler et al., Autoimmunity 18, 149–152, 1994) [1]. In the latt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000e90dbdfc3817b07baff814116debe
https://doi.org/10.1016/0165-2478(96)02589-8

Zobrazit plný text záznamu

Metabolism of cholesterol, phosphatidylethanolamine and stearylamine analogues of GM1 ganglioside by rat glioma C6 cells

Autor: Peter H. Fishman, Tadeusz Pacuszka

Publikováno v: Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1083:153-160

Tritium-labeled neoglycolipids consisting of the oligosaccharide of ganglioside GM1 attached to cholesterol (GM1OSNH-X-CHOL), phosphatidylethanolamine (GM1OS-PE) and stearylamine (GM1OSNHC18) were synthesized and their uptake and metabolism by GM1-de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f22ac72a0911de9237cf3a68783dfa
https://doi.org/10.1016/0005-2760(91)90036-h

Zobrazit plný text záznamu

The ceramide structure of GM1 ganglioside differently affects its recovery in low-density membrane fractions prepared from HL-60 cells with or without triton-X100

Autor: Grazyna Hoser, Tadeusz Pacuszka, Mirosława Panasiewicz, Maciej Kawalec, Hanna Domek, Natalia Fedoryszak

Publikováno v: Cellular & Molecular Biology Letters

Gangliosides are characteristically enriched in various membrane domains that can be isolated as low density membrane fraction insoluble in detergents (detergent-resistant membranes, DRMs) or obtained after homogenization and sonication in 0.5 M sodi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2f6251041a0581a221b74a48672518
http://europepmc.org/articles/PMC6275918

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání