Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tadeusz J. Kaczynski"'
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract TNFRSF10A (tumor necrosis factor receptor superfamily member 10A) encodes a cell surface receptor protein involved in apoptotic, necroptotic, and inflammatory pathways. Dysregulation of TNFRSF10A has been implicated in sensitization to apopt
Externí odkaz:
https://doaj.org/article/576317469deb471f9d53aec97aa27e92
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Long noncoding RNAs (lncRNAs) are emerging as a class of genes whose importance has yet to be fully realized. It is becoming clear that the primary function of lncRNAs is to regulate gene expression, and they do so through a varie
Externí odkaz:
https://doaj.org/article/4258f29514b741c1a63133c48f3e1e67
Autor:
Min Jung Kang, Timothy J Hansen, Monique Mickiewicz, Tadeusz J Kaczynski, Samantha Fye, Shermali Gunawardena
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104617 (2014)
Formation of new synapses or maintenance of existing synapses requires the delivery of synaptic components from the soma to the nerve termini via axonal transport. One pathway that is important in synapse formation, maintenance and function of the Dr
Externí odkaz:
https://doaj.org/article/ce226dc0f9564274b3c7ff28601e4546
Publikováno v:
Molecular vision. 28
Nuclear retention is a mechanism whereby excess RNA transcripts are stored in the event that a cell needs to quickly respond to a stimulus; maintaining proper nuclear-to-cytoplasmic balance is important for cellular homeostasis and cell function. The
Nuclear retention is a mechanism whereby RNA transcripts are held in the nucleus to maintain a proper nuclear-to-cytoplasmic balance or as a stockpile for use in responding to stimuli. Many mechanisms are employed to determine whether transcripts are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aff0a424712d580fb68d96993fdd489
https://doi.org/10.1101/2021.01.07.425741
https://doi.org/10.1101/2021.01.07.425741
Autor:
Tadeusz J. Kaczynski, Tao Liu, Martin R Turner, Fuguo Wu, Louise S. Matheson, Jie Wang, Xiuqian Mu
Both transcriptional and post-transcriptional regulation of gene expression play significant roles in diverse biological processes, but little is known about how post-transcriptional regulation impacts retinal development. Here we report our study of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb915a2edc421cf89d5884f922ce8fa
https://doi.org/10.1101/2020.12.15.422926
https://doi.org/10.1101/2020.12.15.422926
In the current scientific era, where the next-generation sequencing is a commonplace, we are just now beginning to understand the important role of the noncoding genome in diseases of the human eye. Of the noncoding genes, microRNAs (miRNAs) and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7df5eb0bf1febdc0b31e7947b37bea1f
https://doi.org/10.1016/b978-0-12-816222-4.00005-8
https://doi.org/10.1016/b978-0-12-816222-4.00005-8
Autor:
Mohamed H. Abdel-Rahman, Elizabeth D. Au, Milam A. Brantley, Kinga M. Bujakowska, Colleen M. Cebulla, Rui Chen, Jessica N. Cooke Bailey, Frederick H. Davidorf, Eiko K. de Jong, Anneke I. den Hollander, Rachayata Dharmat, Patty P.A. Dhooge, Michael H. Farkas, Kavin Fatehchand, John H. Fingert, Xiaoyi Raymond Gao, Maartje J. Geerlings, Jonathan L. Haines, Carel B. Hoyng, Robert P. Igo, Hacer Isildak, Tadeusz J. Kaczynski, Mariam Lotfy Khaled, Yutao Liu, Leighanne R. Main, Matthew A Miller, Matthew P. Ohr, Robert Pilarski, Emily Place, Claudio Punzo, Riccardo Sangermano, Stephen G. Schwartz, Hilary Scott, Ruifang Sui, Dyon Valkenburg, Carly J. van der Heide, Naomi Wagner, Andrea R. Waksmunski, Hui Wang, Katie Weihbrecht, Hannah Youngblood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f5cb6c321243789bb397ae4989ac126
https://doi.org/10.1016/b978-0-12-816222-4.09992-5
https://doi.org/10.1016/b978-0-12-816222-4.09992-5
Publikováno v:
MethodsX, Vol 6, Iss, Pp 1292-1304 (2019)
RNA-binding proteins (RBPs) are instrumental in the biochemical processing and physiological functioning of non-coding RNAs. Therefore, as interest in non-coding RNAs continues to expand, refining the techniques capable of probing protein-RNA interac
Autor:
Shengguo Li, Steven J. Fliesler, Renzhong Li, Eduardo Solessio, Yumiko Umino, Darshan Sapkota, David M. Sherry, Fuguo Wu, Mengqing Xiang, Tadeusz J. Kaczynski, Maureen Gannon, Xiuqian Mu
Publikováno v:
Journal of Neuroscience. 33:13053-13065
Horizontal cells are interneurons that synapse with photoreceptors in the outer retina. Their genesis during development is subject to regulation by transcription factors in a hierarchical manner. Previously, we showed that Onecut 1 (Oc1), an atypica