Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Tadeusz Bieg"'
Autor:
Magdalena Staniszewska, Agnieszka Bronowicka-Szydełko, Kinga Gostomska-Pampuch, Jerzy Szkudlarek, Arkadiusz Bartyś, Tadeusz Bieg, Elżbieta Gamian, Agata Kochman, Bolesław Picur, Jadwiga Pietkiewicz, Piotr Kuropka, Wiesław Szeja, Jerzy Wiśniewski, Piotr Ziółkowski, Andrzej Gamian
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Non-enzymatic modification of proteins by carbohydrates, known as glycation, leads to generation of advanced glycation end-products (AGEs). In our study we used in vitro generated AGEs to model glycation in vivo. We discovered in vivo analog
Externí odkaz:
https://doaj.org/article/5e928347233642c5a6d161c60deb78d8
Autor:
Wieslaw Szeja, Grzegorz Grynkiewicz, Tadeusz Bieg, Piotr Swierk, Anna Byczek, Katarzyna Papaj, Radosław Kitel, Aleksandra Rusin
Publikováno v:
Molecules, Vol 19, Iss 6, Pp 7072-7093 (2014)
A series of glycoconjugates, derivatives of genistein containing a C-glycosylated carbohydrate moiety, were synthesized and their anticancer activity was tested in vitro in the human cell lines HCT 116 and DU 145. The target compounds 15–17 were sy
Externí odkaz:
https://doaj.org/article/73c89522c53a4f90a9b022dac9b5366f
Autor:
Ilona Wandzik, Wiesław Szeja, Urszula Nawrot, Tadeusz Bieg, Katarzyna Kral, Jadwiga Paszkowska
Publikováno v:
Molecules, Vol 18, Iss 7, Pp 8018-8027 (2013)
New derivatives of uridine which contain a b-ketoenol motif were synthesized, characterized and biologically tested. Synthesized compounds 1–4 showed no activity against bovine milk β-1,4-galactosyltransferase I at concentrations up to 2.0 mM and
Externí odkaz:
https://doaj.org/article/3eb8b60487e5430db9d388d5e49e86ec
Publikováno v:
Current Organic Chemistry. 22:2801-2808
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c92fc8ce9f5359d186a500198ac130
https://doi.org/10.2174/1385272823666181126112958
https://doi.org/10.2174/1385272823666181126112958
Autor:
Piotr Kuropka, Elżbieta Gamian, Kinga Gostomska-Pampuch, Jerzy Szkudlarek, Tadeusz Bieg, Agnieszka Bronowicka-Szydełko, Arkadiusz Bartyś, Jadwiga Pietkiewicz, Bolesław Picur, Andrzej Gamian, Piotr Ziółkowski, Agata Kochman, Magdalena Staniszewska, Jerzy Wiśniewski, Wiesław Szeja
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Non-enzymatic modification of proteins by carbohydrates, known as glycation, leads to generation of advanced glycation end-products (AGEs). In our study we used in vitro generated AGEs to model glycation in vivo. We discovered in vivo analogs of unus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9965546c6227d0d1cafc89d40d3ff948
https://pubmed.ncbi.nlm.nih.gov/33536563
https://pubmed.ncbi.nlm.nih.gov/33536563
Autor:
Tadeusz Bieg, Katarzyna Kral, Agnieszka Kudelko, Aleksandra Dąbrowska, Anna Barabaś, Ilona Wandzik
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 36:159-169
N-substituted isomeric hydrazones of uridyl aldehyde have been synthesized. The occurrence of the dominant E isomers with respect to the azomethine group was confirmed by means of NMR spectroscopy. Synthesized hydrazones feature an acetonide moiety a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc18fa6ddd8cf7d65d2e8f55e4be964a
https://doi.org/10.1080/15257770.2016.1231321
https://doi.org/10.1080/15257770.2016.1231321
Publikováno v:
Journal of Molecular Structure. 1127:532-538
Inclusion complexes formed between β-cyclodextrin (β-CD) and metabolites of catecholamines, i.e. vanillylmandelic acid (VMA), homovanillic acid (HVA) as well as vanillin (VA) were studied using NMR spectroscopy. Due to the importance of these compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c56a3cf0b2b2d37b3e02b1cb6a41df34
https://doi.org/10.1016/j.molstruc.2016.08.010
https://doi.org/10.1016/j.molstruc.2016.08.010
Autor:
Sylwia Waśkiewicz, Małgorzata Burek, Sebastian Student, Anna Lalik, Tadeusz Bieg, Ilona Wandzik
Publikováno v:
Biomaterials Science. 5:234-246
A series of thermoresponsive glycomicrogels with trehalose in the cross-links or with trehalose in the cross-links and as pending moieties was synthesized. These materials were obtained by surfactant-free precipitation copolymerization of N-isopropyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e607d395995781ba83aaa9e095a83a19
https://doi.org/10.1039/c6bm00624h
https://doi.org/10.1039/c6bm00624h
Autor:
Tadeusz Bieg, Katarzyna Kral, Anna Lalik, Katarzyna Włodarczyk, Ilona Wandzik, Przemysław Hahn, Urszula Nawrot
Publikováno v:
Bioorganic Chemistry. 61:13-20
This study described the synthesis and in vitro evaluation of eight new derivatives of uridine as antifungal agents and inhibitors of chitin synthase. Dimeric uridinyl derivatives synthesized by us did not exhibit significant activity. One of the stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd18f1bc8d8abd22905fa6adb051a04
https://doi.org/10.1016/j.bioorg.2015.05.007
https://doi.org/10.1016/j.bioorg.2015.05.007
Autor:
Katarzyna Komor, Wiesław Szeja, Gabriela Pastuch-Gawołek, Tadeusz Bieg, Roman Komor, Nikodem Kuźnik
Publikováno v:
Tetrahedron Letters. 55:3709-3712
We report a new approach for the synthesis of new chiral synthons in which two unsaturated sugars are linked via a glycosidic bond. The di-unsaturated disaccharide can be further functionalized using effective, highly selective methods and used in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d0f993a12336bc3eebbefb188d4c63
https://doi.org/10.1016/j.tetlet.2014.05.025
https://doi.org/10.1016/j.tetlet.2014.05.025