Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Tadeja Rezen"'
Autor:
Miha Moškon, Tadeja Režen
Publikováno v:
Metabolites, Vol 14, Iss 11, p 595 (2024)
Constraint-based modelling and genome-scale metabolic models (GEMs) have been used extensively to analyze omics data, providing a mechanistic perspective on complex metabolic systems and networks [...]
Externí odkaz:
https://doaj.org/article/b5d7d991aa0a4c2b94f6b9623fe474a4
Autor:
Asma Chikhaoui, Meriem Jones, Tadeja Režen, Melika Ben Ahmed, Chokri Naouali, Radovan Komel, Mohamed Zghal, Samir Boubaker, Sonia Abdelhak, Houda Yacoub-Youssef
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Xeroderma pigmentosum (XP) is a DNA repair disease that predisposes to early skin cancers as cutaneous melanoma. Melanoma microenvironment contains inflammatory mediators, which would be interesting biomarkers for the prognosis or for the id
Externí odkaz:
https://doaj.org/article/35dad24228624691ae99529e8ee5fcb5
Autor:
Jure Bedenk, Tadeja Režen, Taja Železnik Ramuta, Nina Jančar, Eda Vrtačnik Bokal, Ksenija Geršak, Irma Virant Klun
Publikováno v:
Reproductive Biology and Endocrinology, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background In vitro maturation (IVM) of oocytes is a laboratory method that allows the maturation of immature (GV) oocytes retrieved from patients enrolled in the in vitro fertilization (IVF) programme. However, this method is still sparsely
Externí odkaz:
https://doaj.org/article/25cb60758a2043b4b133f53d7538039f
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3521-3530 (2021)
Omics data can be integrated into a reference model using various model extraction methods (MEMs) to yield context-specific genome-scale metabolic models (GEMs). How to chose the appropriate MEM, thresholding rule and threshold remains a challenge. W
Externí odkaz:
https://doaj.org/article/db4c20c2164a46089ee4723bddbac05a
Autor:
Aleša Kristan, Tadej Pajič, Aleš Maver, Tadeja Režen, Tanja Kunej, Rok Količ, Andrej Vuga, Martina Fink, Špela Žula, Helena Podgornik, Saša Anžej Doma, Irena Preložnik Zupan, Damjana Rozman, Nataša Debeljak
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
An erythrocytosis is present when the red blood cell mass is increased, demonstrated as elevated hemoglobin and hematocrit in the laboratory evaluation. Congenital predispositions for erythrocytosis are rare, with germline variants in several genes i
Externí odkaz:
https://doaj.org/article/e2d1e10e99874627bc2743516f61c758
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
This review focuses on the role of oxidized sterols in three major gastrointestinal cancers (hepatocellular carcinoma, pancreatic, and colon cancer) and how the circadian clock affects the carcinogenesis by regulating the lipid metabolism and beyond.
Externí odkaz:
https://doaj.org/article/4e46c246b4f64bd59c88c97b097b0b82
Autor:
Katharina F. Heil, Anze Zupanic, Chris T. Evelo, Carole Goble, Kristel Van Steen, Tadeja Rezen, Hans V Westerhoff, Rahuman S. Malik Sheriff, Maria Suarez Diez, Henning Hermjakob, Marco Pagni, Damjana Rozman, Barbara Szomolay, Miguel Rocha, Jasper Koehorst, Alexey Kolodkin, Victoria Dominguez Del Angel, David Šafránek, Dirk Fey, Ilja Arts, Rui Benfeitas, Vitor Martins dos Santos, Mihail Anton, Marek Ostaszewski, Ulrike Wittig, John M. Hancock, Brane Leskošek, Katherine Wolstencroft, Martin Golebiewski, Wolfgang Müller, Polonca Ferk, Kristina Gruden, William T. Scott, Elena Domínguez-Romero, Martina Kutmon, Maria I. Klapa, Sébastien Moretti, Pascal Kahlem
Publikováno v:
F1000Research, Vol 11 (2024)
In this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader community of systems biologists in Europe and worldwide. The Community beli
Externí odkaz:
https://doaj.org/article/231bbdc173f041d7b339528a06d2b5e4
Autor:
Katharina F. Heil, Anze Zupanic, Chris T. Evelo, Carole Goble, Kristel Van Steen, Tadeja Rezen, Hans V Westerhoff, Rahuman S. Malik Sheriff, Maria Suarez Diez, Henning Hermjakob, Marco Pagni, Damjana Rozman, Barbara Szomolay, Miguel Rocha, Jasper Koehorst, Alexey Kolodkin, Victoria Dominguez Del Angel, David Šafránek, Dirk Fey, Ilja Arts, Rui Benfeitas, Vitor Martins dos Santos, Mihail Anton, Marek Ostaszewski, Ulrike Wittig, John M. Hancock, Brane Leskošek, Katherine Wolstencroft, Martin Golebiewski, Wolfgang Müller, Polonca Ferk, Kristina Gruden, Martina Kutmon, Maria I. Klapa, Sébastien Moretti, Pascal Kahlem
Publikováno v:
F1000Research, Vol 11 (2022)
In this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader community of systems biologists in Europe and worldwide. The Community beli
Externí odkaz:
https://doaj.org/article/da5bfc6068504a22a6da45f585378940
Autor:
Cene Skubic, Hana Trček, Petra Nassib, Tinkara Kreft, Andrew Walakira, Katka Pohar, Sara Petek, Tadeja Režen, Alojz Ihan, Damjana Rozman
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110651- (2024)
Summary: Sterols from cholesterol synthesis are crucial for cholesterol production, but also have individual roles difficult to assess in vivo due to essentiality of cholesterol. We developed HepG2 cell models with knockouts (KOs) for three enzymes o
Externí odkaz:
https://doaj.org/article/ebd81049d2e34d6089edf8afcf668a26
Autor:
Eva Kočar, Sonja Katz, Žiga Pušnik, Cene Skubic, Tadeja Režen, Vitor A.P. Martins dos Santos, Miha Mraz, Miha Moškon, Damjana Rozman
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103213- (2024)
Summary: The growing interest in clinical diagnostics has recently focused on metabolic biomarkers. Here, we present a protocol for sample preparation, extraction of cholesterol-related sterols, and quantification of 10 sterols in human blood serum s
Externí odkaz:
https://doaj.org/article/2f867cb2b9084d98950ab77d2ac0f316