Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Tadazumi Komiyama"'
Autor:
Habib Abul Muntasir, Murad Hossain, Mohiuddin Ahmed Bhuiyan, Tadazumi Komiyama, Takashi Nakamura, Masanobu Ozaki, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 3, Pp 274-277 (2007)
Based on radio-ligand binding and molecular modeling studies, sarpogrelate shows a moderate selectivity for 5-HT2B versus 5-HT2A receptors. To confirm the modeling data of sarpogrelate to 5-HT2B receptors predicting interaction of sarpogrelate toward
Externí odkaz:
https://doaj.org/article/ea6f7292e4fd4e53a7f7516a8e6c17ce
Autor:
Maruf Ahmed, Habib Abul Muntasir, Murad Hossain, Masaji Ishiguro, Tadazumi Komiyama, Ikunobu Muramatsu, Hitoshi Kurose, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 2, Pp 167-172 (2006)
We obtained a new mutant of the β1-adrenergic receptor (β1-AR) by point mutations that can constitutively activate β1-AR. Aspartate104 of the β1-AR in the 2nd transmembrane was replaced with alanine. The β1-AR mutant expressed in human embryonic
Externí odkaz:
https://doaj.org/article/3d634c84f06347f5abb44f6077455725
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 1, Pp 55-63 (2006)
The purpose of the present study was to examine 5-hydroxytryptamine (5-HT)2A-receptor sarpogrelate interactions by site-directed mutagenesis. Based on molecular modeling studies, aspartic acid (Asp)155[3.32] and tryptophan (Trp)151[3.28] in transmemb
Externí odkaz:
https://doaj.org/article/ce111e66bd294ef69ae4f21f741d38ca
Autor:
Senthilkumar Krishnaswamy, Tadazumi Komiyama, Masahiko Miyamoto, M. Enamul Kabir, Yasuhiro Furuichi, Dakshnamurthy Selvakumar
Publikováno v:
Microbiology and Immunology. 58:523-529
Immunoassay designs rely on the great specificity of antibodies and a suitable marker that facilitates generation of a quantitative signal. Currently, there is no reliable method for measuring the titers of an anti-idiotypic antibody. Our initial att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741d6f2fdf2a6fa13679a6dc696b29b4
https://doi.org/10.1111/1348-0421.12178
https://doi.org/10.1111/1348-0421.12178
Publikováno v:
Yeast. 29:475-485
Fps1p is an aquaglyceroporin important for turgor regulation of Saccharomyces cerevisiae. Previously we reported the involvement of Fps1p in the yeast-killing action of killer toxin HM-1. The fps1 cells showed a high HM-1-resistant phenotype in hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f8b38b42f6887aa8f4464e9421c8a37
https://doi.org/10.1002/yea.2927
https://doi.org/10.1002/yea.2927
Autor:
M. Enamul Kabir, Tadazumi Komiyama, Masahiko Miyamoto, Mahbubur Rahman, Yasuhiro Furuichi, Senthilkumar Krishnaswamy
Publikováno v:
Journal of Molecular Recognition. 24:631-641
Existing antifungal drugs are notable for their inability to act rapidly, as well as their toxicity and limited spectrum. The identification of fungal-specific genes and virulence factors would provide targets for new and influential drugs. The displ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b6b309f8739475b0798c872754364a
https://doi.org/10.1002/jmr.1075
https://doi.org/10.1002/jmr.1075
Autor:
Masahiko Miyamoto, Tadazumi Komiyama, Yasuhiro Furuichi, M. Enamul Kabir, Mahbubur Rahman, Senthilkumar Krishnaswamy
Publikováno v:
Journal of Immunological Methods. 366:60-68
Aspergillus fumigatus causes the highly lethal form of invasive aspergillosis (IA). In the present study to develop a novel anti-fungal drug for protection against invasive disease, we identified a single chain fragment variable (scFv) antibody (scFv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d70aae36690b0cfb2b2ce0373d321b
https://doi.org/10.1016/j.jim.2011.01.006
https://doi.org/10.1016/j.jim.2011.01.006
Publikováno v:
Yeast. 28:27-41
We screened a set of Saccharomyces cerevisiae deletion mutants for resistance to killer toxin HM-1, which kills susceptible yeasts through inhibiting 1,3-beta-glucan synthase. By using HM-1 plate assay, we found that eight gene-deletion mutants had h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f032a273c2dcdb164211e00f05f133
https://doi.org/10.1002/yea.1818
https://doi.org/10.1002/yea.1818
Autor:
M. Enamul Kabir, Tadazumi Komiyama, Senthilkumar Krishnaswamy, Yasuhiro Furuichi, Masahiko Miyamoto
Publikováno v:
Journal of Biochemistry. 147:723-733
We reported previously competitive panning elution with PBS (pH 7.0) that contains HM-1 killer toxin (HM-1) and Candida albicans membrane fraction (CaMF) to release phages bound with CaMF as an antigen. Here, as an alternative strategy, we isolated h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaec16b4a4e0bcef7108f3db274ff298
https://doi.org/10.1093/jb/mvq006
https://doi.org/10.1093/jb/mvq006
Effects of Anthocyanins on Psychological Stress-Induced Oxidative Stress and Neurotransmitter Status
Publikováno v:
Journal of Agricultural and Food Chemistry. 56:7545-7550
There is strong evidence that oxidative stress participates in the etiology of neurodegenerative diseases such as Parkinson's, and Alzheimer's diseases. Moreover, emotional stress effects in the central nervous system play a vital role in homeostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72fe929f6940ee3c723c546966cd4ed
https://doi.org/10.1021/jf800930s
https://doi.org/10.1021/jf800930s