Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Tadayoshi, Takeuchi"'
Autor:
Yasuyuki Fujimoto, Satomi Hayashi, Yasu-Taka Azuma, Kazunori Mukai, Kazuhiro Nishiyama, Satomi Kita, Ai Morioka, Hidemitsu Nakajima, Takahiro Iwamoto, Tadayoshi Takeuchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 132, Iss 3, Pp 181-186 (2016)
In gastric smooth muscles, the released Ca2+ activates the contractile proteins and Ca2+ taken up from the cytosol cause relaxation. The Na+/Ca2+ exchanger (NCX) is an antiporter membrane protein that controls Ca2+ influx and efflux across the membra
Externí odkaz:
https://doaj.org/article/ba362392ed9041958d91ae56a3c63b35
Autor:
Kazuhiro Nishiyama, Yasu-Taka Azuma, Satomi Kita, Naoki Azuma, Satomi Hayashi, Hidemitsu Nakajima, Takahiro Iwamoto, Tadayoshi Takeuchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 123, Iss 3, Pp 235-245 (2013)
The Na+/Ca2+ exchanger (NCX) is a plasma membrane transporter involved in regulating intracellular Ca2+ concentrations. NCX is critical for Ca2+ regulation in cardiac muscle, vascular smooth muscle, and nerve fibers. To determine the role of NCX1 and
Externí odkaz:
https://doaj.org/article/4b598d7bcb0848aab378e0debcc1b48e
Autor:
Yasu-Taka Azuma, Yukiko Matsuo, Hidemitsu Nakajima, George D. Yancopoulos, David M. Valenzuela, Andrew J. Murphy, Margaret Karow, Tadayoshi Takeuchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 2, Pp 105-111 (2011)
The cytokine, interleukin (IL)-19, is a member of the IL-10 family that includes IL-20, IL-22, IL-24, and IL-26. Recent studies have shown that IL-19 is produced by keratinocytes, epithelial cells, macrophages, and B-cells. Little is known about the
Externí odkaz:
https://doaj.org/article/439cb5f714284438bcc88835505534bd
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 2, Pp 231-241 (2010)
The present study was designed to identify the inhibitory neurotransmitters mediating nonadrenergic noncholinergic relaxation in the longitudinal muscle of C57/BL mouse distal colon. Relaxation induced by electrical field stimulation (EFS) was record
Externí odkaz:
https://doaj.org/article/af8727024b774aeda711808b919e6e2d
Autor:
Kaori Waseda, Tadayoshi Takeuchi, Mayuko Ohta, Yutaka Okishio, Akikazu Fujita, Fumiaki Hata, Tadashi Takewaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 1, Pp 91-100 (2005)
A role of ATP in nonadrenergic, noncholinergic (NANC) relaxations was examined in the Wistar rat jejunum. Electrical field stimulation (EFS) induced NANC relaxation of longitudinal muscle of the jejunal segments in a frequency-dependent manner. A pur
Externí odkaz:
https://doaj.org/article/f43df4b0410b4f4daef076e7dfd77f35
Autor:
Tadayoshi Takeuchi, Kaori Fujinami, Akikazu Fujita, Yutaka Okishio, Tadashi Takewaki, Fumiaki Hata
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 1, Pp 71-80 (2004)
The role of interstitial cells of Cajal (ICC) in electrical field stimulation (EFS)-induced neurogenic responses in ileum was studied by using the ICC-deficient mutant (SLC-W/WV) mouse and its wild type. In the immunohistochemical study with anti-c-K
Externí odkaz:
https://doaj.org/article/91e6373741f54bf7a84922ccc7af654c
Autor:
Akikazu Fujita, Yutaka Okishio, Kaori Fujinami, Masashi Nakagawa, Tadayoshi Takeuchi, Tadashi Takewaki, Fumiaki Hata
Publikováno v:
Journal of Pharmacological Sciences, Vol 96, Iss 4, Pp 483-492 (2004)
We examined the role of interstitial cells of Cajal (ICC) in the ascending and descending neural reflexes in the ileal segments prepared from wild type mice and c-kit mutant W/WV mice. Localized distension of the ileal segments from wild type mice wi
Externí odkaz:
https://doaj.org/article/cf937b350af5405ea27d77e3a5f6b126
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 1, Pp 35-42 (2003)
In the present study, we examined the expression and the localization of apamin-sensitive small conductance Ca2+-activated K+ channels (SK channels) in the mouse intestine. SK3-immunoreactivity (IR) was detected in both ileum and colon. Double staini
Externí odkaz:
https://doaj.org/article/c4869b6baa714da987643da953db6f18
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 4, Pp 374-380 (2003)
The role of ATP newly synthesized from ADP and phosphocreatine (PC) by creatine kinase (CK) in the contraction of tonic type smooth muscle, rat femoral artery was studied, since its necessity for phasic type smooth muscle was previously shown. In α-
Externí odkaz:
https://doaj.org/article/87596d90c34d4547a2fa05c3027549e4
Publikováno v:
Journal of Pharmacological Sciences, Vol 91, Iss 4, Pp 277-284 (2003)
Since it was suggested in our previous study that ATP newly synthesized from ADP and phosphocreatine (PCr) by creatine kinase had an important role in Ca2+-induced phasic contraction in α-toxin permeabilized smooth muscle of rat proximal colon, we s
Externí odkaz:
https://doaj.org/article/8bbf304b6ad9465788de8ce9a65d899f