Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Tadashi Okubo"'
Autor:
Soichiro Saito, Shuji Mizumoto, Tsukasa Yonekura, Rina Yamashita, Kenta Nakano, Tadashi Okubo, Shuhei Yamada, Tadashi Okamura, Tatsuya Furuichi
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284292 (2023)
SLC35A3 is considered an uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) transporter in mammals and regulates the branching of N-glycans. A missense mutation in SLC35A3 causes complex vertebral malformation (CVM) in cattle. However, the biologic
Externí odkaz:
https://doaj.org/article/37f802978ebc4c5f9b1d7095a09c706e
Autor:
Yuji Yokozeki, Kentaro Uchida, Ayumu Kawakubo, Mitsufumi Nakawaki, Tadashi Okubo, Masayuki Miyagi, Gen Inoue, Makoto Itakura, Hiroyuki Sekiguchi, Masashi Takaso
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Intervertebral disc (IVD) degeneration is a major cause of low back pain (LBP). Following disc injury, nerve growth factor (NGF) concentrations rise in IVDs, and anti-NGF therapy has been shown to attenuate LBP in humans. Increase
Externí odkaz:
https://doaj.org/article/4883f062c4c54a20b245cdeaa73fb551
Autor:
Manabu Mukai, Kentaro Uchida, Tadashi Okubo, Shotaro Takano, Toshihide Matsumoto, Masashi Satoh, Gen Inoue, Masashi Takaso
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Bone marrow-derived monocytes/macrophages are recruited into synovial tissue, where they contribute to synovial inflammation in osteoarthritis through inflammatory cytokine production. Recent studies have suggested that V-Set and transmem
Externí odkaz:
https://doaj.org/article/fe716f1c056f4c3a82cdb7cbf891669b
Autor:
Shintaro Saegusa, Masahiro Fukaya, Wataru Kakegawa, Manabu Tanaka, Osamu Katsumata, Takeyuki Sugawara, Yoshinobu Hara, Makoto Itakura, Tadashi Okubo, Toshiya Sato, Michisuke Yuzaki, Hiroyuki Sakagami
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216960 (2019)
ADP ribosylation factor 6 (Arf6) is a small GTPase that regulates various neuronal events including formation of the axon, dendrites and dendritic spines, and synaptic plasticity through actin cytoskeleton remodeling and endosomal trafficking. EFA6C,
Externí odkaz:
https://doaj.org/article/4c0abf6b9e874d7b91bbbfce6a46dbe6
Autor:
Ayumu Kawakubo, Makoto Itakura, Kentaro Uchida, Yuji Yokozeki, Masashi Takaso, Mitsufumi Nakawaki, Gen Inoue, Hiroyuki Sekiguchi, Tadashi Okubo, Masayuki Miyagi
Publikováno v:
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-10 (2021)
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-10 (2021)
Background Intervertebral disc (IVD) degeneration is a major cause of low back pain (LBP). Following disc injury, nerve growth factor (NGF) concentrations rise in IVDs, and anti-NGF therapy has been shown to attenuate LBP in humans. Increased levels
Publikováno v:
Developmental Dynamics.
Background Pharyngeal arches (PA) are sequentially generated in an anterior-to-posterior order. Ripply3 is essential for posterior PA development in mouse embryos and its expression is sequentially activated in ectoderm and endoderm prior to formatio
Publikováno v:
International Journal of Developmental Neuroscience. 66:1-8
Dopamine is widely involved in behaviors related to motor activity, cognition, motivation, and reward. Dopamine signal is transduced through the dopamine receptor gene family. The dopamine D1 receptor (D1R) is highly expressed in the striatum, and is
Autor:
Wataru Kakegawa, Osamu Katsumata, Takeyuki Sugawara, Yoshinobu Hara, Michisuke Yuzaki, Toshiya Sato, Hiroyuki Sakagami, Masahiro Fukaya, Makoto Itakura, Shintaro Saegusa, Manabu Tanaka, Tadashi Okubo
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216960 (2019)
PLoS ONE
PLoS ONE
ADP ribosylation factor 6 (Arf6) is a small GTPase that regulates various neuronal events including formation of the axon, dendrites and dendritic spines, and synaptic plasticity through actin cytoskeleton remodeling and endosomal trafficking. EFA6C,
Publikováno v:
Development, growthdifferentiation. 60(2)
During tissue development, the morphogenesis of epithelial sheets is regulated by many factors, including mechanical force, although the underlying mechanisms remain largely unknown. In the pharyngeal region of the vertebrate embryo, endodermal epith
Autor:
Tadashi Okubo, Shinji Takada
Publikováno v:
Developmental Dynamics. 244:874-887
Background: The pharyngeal arches (PAs) generate cranial organs including the tongue. The taste placodes, formed in particular locations on the embryonic tongue surface, differentiate into taste buds harbored in distinct gustatory papillae. The devel