Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Tadashi Nakata"'
Publikováno v:
Organic Letters. 19:3203-3206
Stereoselective synthesis of the ent-ZA'B'C'D'-ring system of maitotoxin has been accomplished through a convergent strategy utilizing Suzuki-Miyaura cross coupling reaction of ZA'-ring alkylborane and C'D'-ring (Z)-vinyl iodide, and subsequent const
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633dded30db2924d8a0477f056dca5e5
https://doi.org/10.1021/acs.orglett.7b01301
https://doi.org/10.1021/acs.orglett.7b01301
Autor:
Tomohiro Kimura, Tadashi Nakata, Teruo Kutsuma, Tsutomu Yokomatsu, Yoshinori Yamamoto, Tadashi Kataoka, Huo Zhibao, Yasushi Kawase, Takehiro Yamagishi
Publikováno v:
Organic Process Research & Development. 16:495-498
Sodium monobenzoxyborohydride, which is easily prepared from sodium borohydride and benzoic acid in THF in situ, is treated with α-picoline in THF under mild conditions to give α-picoline–borane in an excellent yield. This method can be a practic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af1b9d13b998525fb0b477d83b5fcb07
https://doi.org/10.1021/op2003858
https://doi.org/10.1021/op2003858
Autor:
Yuko Izuchi, Nobuhiro Kanomata, Yayoi Hongo, Tadashi Nakata, Hiroyuki Koshino, Shunya Takahashi
Publikováno v:
Tetrahedron: Asymmetry. 22:246-251
The formal total synthesis of aspergillide A 1 is described. The cross-metathesis of enone 6 with 6-hepten-2-ol derivative 5 provided E-olefin 15 corresponding to the C4–C14 backbone of 1. The CBS asymmetric reduction of 15 gave allyl alcohol 16, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c49c080e775b5865d09fd8a252079f8
https://doi.org/10.1016/j.tetasy.2011.01.016
https://doi.org/10.1016/j.tetasy.2011.01.016
Autor:
Tadashi Nakata, Tomohiro Kimura
Publikováno v:
Tetrahedron: Asymmetry. 21:1389-1395
SmI 2 -induced reaction of ( E )- and (Z)-β-alkoxyvinyl sulfones onto an aldehyde function afforded 2,6- syn -2,3- trans - and 2,6- syn -2,3- cis -tetrahydropyran-3-ols, respectively, via stereoselective cyclization. This reaction was applied to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e6f369160e8f37aee271ecd0989e8e8
https://doi.org/10.1016/j.tetasy.2010.04.066
https://doi.org/10.1016/j.tetasy.2010.04.066
Autor:
Tadashi Kataoka, Tsutomu Yokomatsu, Kimio Ueda, Teruo Kutsuma, Takeo Iwakuma, Takehiro Yamagishi, Yasushi Kawase, Tadashi Nakata
Publikováno v:
Synthesis. 2010:1673-1677
A convenient method for N-protection of amino acid derivatives with a benzyl group by reductive alkylation of amino acid derivatives with α-picoline-borane is described. Amino acid esters or amino alcohols were treated with aryl aldehydes in methano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a3d2a09d10bb4c43e2a6b4b1d0345c0
https://doi.org/10.1055/s-0029-1218707
https://doi.org/10.1055/s-0029-1218707
Publikováno v:
Tetrahedron. 65:10893-10900
SmI 2 -induced reaction of ( E )-β-alkoxyvinyl ( R )- and ( S )-sulfoxides with aldehydes effected a highly stereoselective intramolecular cyclization to give 2,6- anti -2,3- cis - and 2,6- syn -2,3- trans -tetrahydropyran-3-ols, respectively. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f219d0deb5cbf7432c970c5cabaed0
https://doi.org/10.1016/j.tet.2009.10.082
https://doi.org/10.1016/j.tet.2009.10.082
Publikováno v:
Tetrahedron Letters. 50:3597-3601
Total synthesis of theopederin B, isolated from marine sponge, was accomplished by coupling pederic acid, as the left half, with trioxodecaline amine as the right half. Key reactions for synthesizing the amine were SmI 2 -promoted Reformatsky reactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b08055aa77bc20cc4c1a180e2ff3890
https://doi.org/10.1016/j.tetlet.2009.03.066
https://doi.org/10.1016/j.tetlet.2009.03.066
Autor:
Tatsuo Saito, Tadashi Nakata
Publikováno v:
Organic Letters. 11:113-116
Stereoselective synthesis of a trans-fused 7,6,6,7-membered tetracyclic ether, corresponding to the EFGH-ring of gambierol and the BCDE-ring of gambieric acids, was efficiently accomplished via a two-directional approach. The key reactions were SmI(2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7275ca15160e67bbdfcdb8407d4f5ae
https://doi.org/10.1021/ol8024555
https://doi.org/10.1021/ol8024555
Publikováno v:
Tetrahedron Letters. 49:6462-6465
Stereoselective synthesis of (−)-centrolobine, an anti-Leishmania agent, was accomplished via an intramolecular Barbier-type reaction of iodo-ester with n- or t-butyllithium followed by Lewis acid-promoted Et3SiH reduction of the resulting hemiacet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba89c9979fa867ced5079df76b2949cd
https://doi.org/10.1016/j.tetlet.2008.08.102
https://doi.org/10.1016/j.tetlet.2008.08.102
Publikováno v:
Organic Letters. 10:1675-1678
The stereoselective synthesis of the maitotoxin C'D'E'F'-ring system having a side chain has been accomplished through a convergent strategy. The key reactions include Horner-Wadsworth-Emmons coupling of the C'D'E'-ring and the side chain and subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb905a4bb9e89e3775201d7d013034a
https://doi.org/10.1021/ol800267x
https://doi.org/10.1021/ol800267x